7631-90-5 | Sodium bisulfite

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$26.00	$18.00
25g	95%	in stock	$34.00	$24.00
100g	95%	in stock	$66.00	$47.00
500g	95%	in stock	$155.00	$108.00

Description

• Catalog Number: AB79073
• Chemical Name: Sodium bisulfite
• CAS Number: 7631-90-5
• Molecular Formula: HNaO3S
• Molecular Weight: 104.0609
• MDL Number: MFCD00003530
• SMILES: [O-]S(=O)O.[Na+]

Computed Properties

• Complexity: 33.9
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 5
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1

Literature

• Sulfur Dioxide Contributes to the Cardiac and Mitochondrial Dysfunction in Rats.

  Toxicological sciences : an official journal of the Society of Toxicology 20160601

• Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type.

  Biochemical and biophysical research communications 20140822

• Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity.

  Chemico-biological interactions 20130225

• Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense.

  Bioorganic & medicinal chemistry letters 20121201

• The vasorelaxant effect and its mechanisms of sodium bisulfite as a sulfur dioxide donor.

  Chemosphere 20121001

• The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine.

  Nature protocols 20121001

• Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1.

  Bioorganic & medicinal chemistry letters 20120901

• Single nucleotide analysis of cytosine methylation by whole-genome shotgun bisulfite sequencing.

  Current protocols in molecular biology 20120701

• Bisulfite genomic sequencing of DNA from dried blood spot microvolume samples.

  Forensic science international. Genetics 20120501

• Determination of the heterogeneity of DNA methylation by combined bisulfite restriction analysis and capillary electrophoresis with laser-induced fluorescence.

  Journal of chromatography. A 20120323

• Isolation of glycinin (11S) from lipid-reduced soybean flour: effect of processing conditions on yields and purity.

  Molecules (Basel, Switzerland) 20120309

• Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana.

  Bioorganic & medicinal chemistry letters 20120201

• Quantification of andrographolide sodium bisulphite in urine after intravenous injection to rats by LC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120101

• Genome-wide methylation analysis.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Measuring δ(13)C values of atmospheric acetaldehyde via sodium bisulfite adsorption and cysteamine derivatisation.

  Isotopes in environmental and health studies 20120101

• Transcriptional regulation of hTREX84 in human cancer cells.

  PloS one 20120101

• SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons.

  Toxicological sciences : an official journal of the Society of Toxicology 20111201

• DNA methylation as a risk factor in the effects of early life stress.

  Brain, behavior, and immunity 20111101

• Stress-induced depressive behaviors are correlated with Par-4 and DRD2 expression in rat striatum.

  Behavioural brain research 20111001

• High titer ethanol production from simultaneous enzymatic saccharification and fermentation of aspen at high solids: a comparison between SPORL and dilute acid pretreatments.

  Bioresource technology 20111001

• Regulation of NAD(P)H dehydrogenase-dependent cyclic electron transport around PSI by NaHSO₃ at low concentrations in tobacco chloroplasts.

  Plant & cell physiology 20111001

• Anthocyanins remain stable during commercial blackcurrant juice processing.

  Journal of food science 20110801

• Catalytic enantioselective addition of sodium bisulfite to chalcones.

  Angewandte Chemie (International ed. in English) 20110718

• Proteomic alterations in mouse kidney induced by andrographolide sodium bisulfite.

  Acta pharmacologica Sinica 20110701

• Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium.

  Bioorganic & medicinal chemistry letters 20110615

• Tyrosinase inhibitory activity of a 6-isoprenoid-substituted flavanone isolated from Dalea elegans.

  Bioorganic & medicinal chemistry 20110601

• Stimuli response of cystamine-core dendrimer revealed by diffusion and NOE NMR studies.

  The journal of physical chemistry. B 20110414

• Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.

  Bioorganic & medicinal chemistry 20110315

• A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes.

  Genome research 20110301

• Shortage of bisulfite-free preservative-free epinephrine for intracameral use.

  Journal of cataract and refractive surgery 20110301

• Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes.

  Epigenetics 20110201

• Preparation of a novel hybrid organic-inorganic monolith for the separation of lysozyme by high performance liquid chromatography.

  Journal of chromatography. A 20110107

• Microwave assisted one pot synthesis of some novel 2,5-disubstituted 1,3,4-oxadiazoles as antifungal agents.

  Bioorganic & medicinal chemistry letters 20110101

• Leukocyte DNA methylation signature differentiates pancreatic cancer patients from healthy controls.

  PloS one 20110101

• Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors.

  PloS one 20110101

• Strategies for detecting genomic DNA methylation: a survey of US patents.

  Recent patents on DNA & gene sequences 20100601

• Ethanol production from SPORL-pretreated lodgepole pine: preliminary evaluation of mass balance and process energy efficiency.

  Applied microbiology and biotechnology 20100501

• On energy consumption for size-reduction and yields from subsequent enzymatic saccharification of pretreated lodgepole pine.

  Bioresource technology 20100401

• Development of a sensitive deaminated single-strand conformation polymorphism (DSSCP).

  Applied biochemistry and biotechnology 20100301

• Sodium bisulfite improves rhizome yield and quality in Paris polyphylla.

  Planta medica 20100301

• Principles and challenges of genomewide DNA methylation analysis.

  Nature reviews. Genetics 20100301

• Effects of intracameral use of adrenalin solution with preservative on corneal endothelium.

  Cutaneous and ocular toxicology 20100301

• New amphoteric flocculant containing beta-cyclodextrin, synthesis, characterization and decolorization properties.

  Journal of hazardous materials 20100115

• Accurate sodium bisulfite sequencing in plants.

  Epigenetics 20100101

• Analysis of DNA methylation in plants by bisulfite sequencing.

  Methods in molecular biology (Clifton, N.J.) 20100101

• Dechlorination of chloroacetanilide herbicides by plant growth regulator sodium bisulfite.

  Water research 20090801

• Synthesis of gem-disubstituted taurines by the regioselective ring-opening of 2,2-disubstituted aziridines with sodium bisulfite and sulfite.

  Amino acids 20090701

• Detection method for methylation density on microarray using methyl-CpG-binding domain protein.

  Analytical biochemistry 20090415

• A novel anti-calcification strategy of bovine pericardium using sodium bisulfite modification.

  The Journal of heart valve disease 20090301

• The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae.

  International journal of cancer 20090215

• Melting curve assays for DNA methylation analysis.

  Methods in molecular biology (Clifton, N.J.) 20090101

• [Methods for detection of methylated cytosine residues in DNA].

  Molekuliarnaia biologiia 20090101

• Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells.

  Neoplasia (New York, N.Y.) 20081101

• Cloning and characterization of uracil-DNA glycosylase and the biological consequences of the loss of its function in the nematode Caenorhabditis elegans.

  Mutagenesis 20080901

• Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning.

  Nature 20080313

• The bisulfite genomic sequencing used in the analysis of epigenetic states, a technique in the emerging environmental genotoxicology research.

  Mutation research 20080101

• DNA methylation patterns in bladder cancer and washing cell sediments: a perspective for tumor recurrence detection.

  BMC cancer 20080101

• Kismeth: analyzer of plant methylation states through bisulfite sequencing.

  BMC bioinformatics 20080101

• DNA methylation and mRNA expression of SYN III, a candidate gene for schizophrenia.

  BMC medical genetics 20080101

• DNA methylation analysis using CpG microarrays is impaired in benzopyrene exposed cells.

  Toxicology and applied pharmacology 20071215

• [Hemocompatibility of bovine pericardium with additional sodium bisulfite treatment].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20071001

• Promoter hypermethylation of death-associated protein kinase gene in cholangiocarcinoma.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20070801

• Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701

• Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070601

• Methylation-sensitive single-nucleotide primer extension (Ms-SNuPE) for quantitative measurement of DNA methylation.

  Nature protocols 20070101

• The reduced expression and aberrant methylation of p16(INK4a) in chromate workers with lung cancer.

  Lung cancer (Amsterdam, Netherlands) 20060901

• Inhibition of superoxide dismutase, Vitamin C and glutathione on chemiluminescence produced by luminol and the mixture of sulfite and bisulfite.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501

• Methylation of p16 and Ras association domain family protein 1a during colorectal malignant transformation.

  Molecular cancer research : MCR 20060501

• Hypermethylation of NAD(P)H: quinone oxidoreductase 1 (NQO1) gene in human hepatocellular carcinoma.

  Journal of hepatology 20050401

• Acidic conditions enhance bactericidal effects of sodium bisulfite on Helicobacter pylori.

  Helicobacter 20050401

• [Simultaneous determination of Cl- and SO4(2-) in 30% sodium bisulfite solution samples by ion chromatography].

  Se pu = Chinese journal of chromatography 20050301

• A quantitative DNA methylation assay using mismatch hybridization and chemiluminescence.

  Biomedical and environmental sciences : BES 20050201

• Genetic diversity at the FMR1 locus in Mexican population.

  Archives of medical research 20050101

• Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041115

• Hypermethylation of the inducible nitric-oxide synthase gene promoter inhibits its transcription.

  The Journal of biological chemistry 20041105

• Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells.

  Nature structural & molecular biology 20041101

• In defense of in vitro findings.

  Anesthesiology 20041101

• Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma.

  The American journal of pathology 20041101

• Detailed investigation of the production of the bread flavor component 6-acetyl-1,2,3,4-tetrahydropyridine in proline/1,3-dihydroxyacetone model systems.

  Journal of agricultural and food chemistry 20040908

• The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation.

  The Journal of biological chemistry 20040813

• Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.

  The Journal of biological chemistry 20040702

• Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040615

• Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells.

  The Journal of biological chemistry 20040423

• 5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.

  The Journal of biological chemistry 20040409

• Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040401

• Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.

  Molecular carcinogenesis 20040101

• Sodium bisulfite: scapegoat for chloroprocaine neurotoxicity?

  Anesthesiology 20040101

• Evaluation of DNA methylation in the human genome: why examine it and what method to use.

  European journal of gynaecological oncology 20040101

• Methylation-specific PCR unraveled.

  Cellular oncology : the official journal of the International Society for Cellular Oncology 20040101

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  Cancer letters 20031208

• ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma.

  International journal of cancer 20031101

• Telomerase alone extends the replicative life span of human skeletal muscle cells without compromising genomic stability.

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• Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation.

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• Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas.

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• Detection of gene promoter hypermethylation in fine needle washings from breast lesions.

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• Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma.

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• Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer.

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• HCO(3)(-)-dependent soluble adenylyl cyclase activates cystic fibrosis transmembrane conductance regulator in corneal endothelium.

  American journal of physiology. Cell physiology 20030501

• Methylation of TFPI-2 gene is not the sole cause of its silencing.

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• Allergy and toxic reactions to local anesthetics.

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• Reply to Dr. Moore.

  Regional anesthesia and pain medicine 20030101

• A model system study of the inhibition of heterocyclic aromatic amine formation by organosulfur compounds.

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• Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays.

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• Effects of derivatives of sulfur dioxide on micronuclei formation in mouse bone marrow cells in vivo.

  Bulletin of environmental contamination and toxicology 20020801

• Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.

  British journal of cancer 20020617

• Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs.

  Cancer biology & therapy 20020101

• Determination of a non-methylated deoxycytidine residue in the recognition site of DNA-methyltransferases.

  Biochemistry. Biokhimiia 20011201

• Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis.

  Oncogene 20011108

• Stability of apomorphine hydrochloride in aqueous sodium bisulphite solutions.

  Progress in neuro-psychopharmacology & biological psychiatry 20011001

• KG-1 and KG-1a model the p15 CpG island methylation observed in acute myeloid leukemia patients.

  Leukemia research 20011001

• Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines.

  Japanese journal of cancer research : Gann 20010901

• Site-specific methylation of the promoter alters deoxyribonucleic acid-protein interactions and prevents follicle-stimulating hormone receptor gene transcription.

  Biology of reproduction 20010201

• Eosinophilic explant carditis with eosinophilia: ?Hypersensitivity to dobutamine infusion.

  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 19950101

• Seizures associated with high-dose intravenous morphine containing sodium bisulfite preservative.

  The Annals of pharmacotherapy 19921201

• Grand mal seizures associated with high-dose intravenous morphine infusions: incidence and possible etiology.

  Pain 19921101

• The role of 2-chloroprocaine and sodium bisulfite in rat sciatic nerve edema.

  Journal of neuropathology and experimental neurology 19860901

• Chronic neurological deficits and Nesacaine-CE--an effect of the anesthetic, 2-chloroprocaine, or the antioxidant, sodium bisulfite?

  Anesthesia and analgesia 19840401