765-87-7 | 1,2-Cyclohexanedione

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$12.00	$8.00
1g	96%	in stock	$15.00	$10.00
5g	96%	in stock	$21.00	$15.00
10g	96%	in stock	$35.00	$25.00
25g	96%	in stock	$61.00	$43.00
100g	96%	in stock	$242.00	$169.00
500g	96%	in stock	$981.00	$687.00

Description

• Catalog Number: AI56126
• Chemical Name: 1,2-Cyclohexanedione
• CAS Number: 765-87-7
• Molecular Formula: C6H8O2
• Molecular Weight: 112.1265
• MDL Number: MFCD00001648
• SMILES: C1CCC(=O)C(=O)C1

Computed Properties

• Complexity: 111
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• XLogP3: -0.1

Literature

• Base-catalyzed dehydration of 3-substituted benzene cis-1,2-dihydrodiols: stabilization of a cyclohexadienide anion intermediate by negative aromatic hyperconjugation.

  Journal of the American Chemical Society 20120829

• Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family.

  The FEBS journal 20120401

• Three novel Bi(III) complexes with in situ generated anilate ligands: unusual oxidation of cyclohexanedione to dihydroxy benzoquinone.

  Dalton transactions (Cambridge, England : 2003) 20120207

• Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics.

  The Journal of organic chemistry 20111216

• Mechanism of resistance to ACCase-inhibiting herbicides in wild oat (Avena fatua ) from Latin America.

  Journal of agricultural and food chemistry 20110713

• Theoretical study of oxidation of cyclohexane diol to adipic anhydride by [Ru(IV)(O)(tpa)(H2O)]2+ complex (tpa ═ tris(2-pyridylmethyl)amine).

  Inorganic chemistry 20110704

• Bis[bis-(4,4'-dimethyl-2,2'-bipyridine)(10,11,12,13-tetra-hydro-dipyrido[3,2-a:2',3'-c]phenazine)ruthenium(II)] tetra-kis(perchlorate) acetonitrile disolvate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20100501

• Cooperative strengthening of an intramolecular O-H...O hydrogen bond by a weak C-H...O counterpart: matrix-isolation infrared spectroscopy and quantum chemical studies on 3-methyl-1,2-cyclohexanedione.

  The journal of physical chemistry. A 20100204

• Bis(2,9-dimethyl-1,10-phenanthroline-κN,N')(10,11,12,13-tetra-hydro-dipyrido[3,2-a:2',3'-c]phenazine-κN,N)ruthenium(II) bis-(perchlorate) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20100201

• Electron transfer as a potential cause of diacetyl toxicity in popcorn lung disease.

  Reviews of environmental contamination and toxicology 20100101

• Multifaceted approach to resveratrol bioactivity: Focus on antioxidant action, cell signaling and safety.

  Oxidative medicine and cellular longevity 20100101

• Arginine, a key residue for the enhancing ability of an antifreeze protein of the beetle Dendroides canadensis.

  Biochemistry 20091013

• Total synthesis of the strychnos alkaloid (+)-minfiensine: tandem enantioselective intramolecular Heck-iminium ion cyclization.

  Journal of the American Chemical Society 20080416

• Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.

  BMC biochemistry 20080101

• Diversity-oriented synthesis of enantiomerically pure steroidal tetracycles employing Stille/Diels-Alder reaction sequences.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Cationic rhodium(I)/segphos-catalyzed cycloisomerization of 1,6- and 1,7-diynes in the presence of 1,2-cyclohexanedione.

  Organic letters 20070927

• Semiconductor surface-induced 1,3-hydrogen shift: the role of covalent vs zwitterionic character.

  Journal of the American Chemical Society 20060830

• Reduction of activated carbonyl groups by alkyl phosphines: formation of alpha-hydroxy esters and ketones.

  Chemical communications (Cambridge, England) 20060321

• The molecular bases for resistance to acetyl co-enzyme A carboxylase (ACCase) inhibiting herbicides in two target-based resistant biotypes of annual ryegrass (Lolium rigidum).

  Planta 20060201

• Basis of selectivity of cyhalofop-butyl in Oryza sativa L.

  Planta 20060101

• Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2.

  Cellular and molecular life sciences : CMLS 20060101

• Decrease in pH strongly enhances binding of native, proteolyzed, lipolyzed, and oxidized low density lipoprotein particles to human aortic proteoglycans.

  The Journal of biological chemistry 20051111

• Structure-sweetness relationship in egg white lysozyme: role of lysine and arginine residues on the elicitation of lysozyme sweetness.

  Chemical senses 20051001

• Synthesis of new dihydropyrazines with DNA strand-breakage activity.

  Chemical & pharmaceutical bulletin 20051001

• Sequential catalytic asymmetric Heck-iminium ion cyclization: enantioselective total synthesis of the Strychnos alkaloid minfiensine.

  Journal of the American Chemical Society 20050727

• A one-pot isomerization-arylation of 2,3-epoxycyclohexanone under controlled microwave heating.

  The Journal of organic chemistry 20050610

• The receptor binding domain of apolipoprotein E is responsible for its antioxidant activity.

  Biochemistry 20050524

• Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

  Journal of medicinal chemistry 20050421

• Synthesis and antiapoptotic activity of a novel analogue of the neutral sphingomyelinase inhibitor scyphostatin.

  Chembiochem : a European journal of chemical biology 20050401

• Chemical modification of arginine residues of Notechis scutatus scutatus notexin.

  Toxicon : official journal of the International Society on Toxinology 20041001

• EK-2612, a new cyclohexane-1,3-dione possessing selectivity between rice (Oryza sativa) and barnyardgrass (Echinochloa crus-galli).

  Pest management science 20040901

• Use of resistant ACCase mutants to screen for novel inhibitors against resistant and susceptible forms of ACCase from grass weeds.

  Journal of agricultural and food chemistry 20040811

• Suppressive activity of protease inhibitors from buckwheat seeds against human T-acute lymphoblastic leukemia cell lines.

  Applied biochemistry and biotechnology 20040501

• Streptavidin in antibody pretargeting. 4. Site-directed mutation provides evidence that both arginine and lysine residues are involved in kidney localization.

  Bioconjugate chemistry 20040101

• Cyclohexanedione herbicides are inhibitors of rat heart acetyl-CoA carboxylase.

  Bioorganic & medicinal chemistry letters 20031006

• Use of plant cell cultures to study graminicide effects on lipid metabolism.

  Phytochemistry 20030701

• An isoleucine residue within the carboxyl-transferase domain of multidomain acetyl-coenzyme A carboxylase is a major determinant of sensitivity to aryloxyphenoxypropionate but not to cyclohexanedione inhibitors.

  Plant physiology 20030701

• In vitro degradation of willow salicylates.

  Journal of chemical ecology 20030501

• Solid-phase fluoroimmunoassay for the determination of mesotrione--a novel triketone herbicide--in water with direct measurement of the fluorescence onto the solid support.

  The Analyst 20030401

• Characterisation of target-site resistance to ACCase-inhibiting herbicides in the weed Alopecurus myosuroides (black-grass).

  Pest management science 20030201

• Electron-beam treatment of aromatic hydrocarbons that can be air-stripped from contaminated groundwater. 1. Model studies in aqueous solution.

  Environmental science & technology 20030115

• Oxidative cleavage of the C-C bond of 3,6-dialkylcyclohexane-1,2-diones by cell suspension cultures of Marchantia polymorpha.

  Phytochemistry 20021101

• Synthesis of 7-substituted benzolactam-V8s and their selectivity for protein kinase C isozymes.

  Organic letters 20020711

• Synthesis of eight- and nine-membered carbocycles through a ring-closing metathesis/ring fragmentation strategy: a rapid and versatile approach to bicyclo[6.4.0]- and bicyclo[7.4.0]alkene ring systems.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020702

• Effects of modifications of alpha-crystallin on its chaperone and other properties.

  The Biochemical journal 20020615

• PCR-based detection of resistance to acetyl-CoA carboxylase-inhibiting herbicides in black-grass (Alopecurus myosuroides Huds) and ryegrass (Lolium rigidum gaud).

  Pest management science 20020501

• An isoleucine-leucine substitution in chloroplastic acetyl-CoA carboxylase from green foxtail (Setaria viridis L. Beauv.) is responsible for resistance to the cyclohexanedione herbicide sethoxydim.

  Planta 20020101

• Streptavidin in antibody pretargeting. 3. Comparison of biotin binding and tissue localization of 1,2-cyclohexanedione and succinic anhydride modified recombinant streptavidin.

  Bioconjugate chemistry 20020101

• Intercalation of multiple carbon atoms between the carbonyls of alpha-diketones.

  The Journal of organic chemistry 20011005

• Differences in host use efficiency of larvae of a generalist moth, Operophtera brumata on three chemically divergent Salix species.

  Journal of chemical ecology 20010801

• Resistance to ACCase-inhibiting herbicides and isoproturon in UK populations of Lolium multiflorum: mechanisms of resistance and implications for control.

  Pest management science 20010701

• Polyclonal-based ELISA for the identification of cyclohexanedione analogs that inhibit maize acetyl coenzyme-A carboxylase.

  Journal of AOAC International 20010101

• Evidence for an essential arginine in the flavoprotein nitroalkane oxidase.

  Journal of enzyme inhibition 20010101

• Chemical modifications of Serratia marcescens anthranilate synthase component I.

  The Journal of biological chemistry 19811010