7693-46-1 | 4-Nitrophenyl chloroformate

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$8.00	$5.00
100g	98%	in stock	$25.00	$17.00
500g	98%	in stock	$100.00	$70.00

Description

• Catalog Number: AB48378
• Chemical Name: 4-Nitrophenyl chloroformate
• CAS Number: 7693-46-1
• Molecular Formula: C7H4ClNO4
• Molecular Weight: 201.564
• MDL Number: MFCD00007321
• SMILES: ClC(=O)Oc1ccc(cc1)[N+](=O)[O-]

Computed Properties

• Complexity: 207
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• XLogP3: 2.6

Literature

• Use of Linear Free Energy Relationships (LFERs) to elucidate the mechanisms of reaction of a γ-methyl-β-alkynyl and an ortho-substituted aryl chloroformate ester.

  International journal of molecular sciences 20120101

• Construction of paclitaxel-loaded poly (2-hydroxyethyl methacrylate)-g-poly (lactide)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine copolymer nanoparticle delivery system and evaluation of its anticancer activity.

  International journal of nanomedicine 20120101

• Impact of the nature and size of the polymeric backbone on the ability of heterobifunctional ligands to mediate shiga toxin and serum amyloid p component ternary complex formation.

  Toxins 20110901

• Synthesis and transdermal permeation of novel N4-methoxypoly(ethylene glycol) carbamates of cytarabine.

  Drug development and industrial pharmacy 20101201

• Analysis of the nucleophilic solvation effects in isopropyl chlorothioformate solvolysis.

  International journal of molecular sciences 20100101

• Synthesis of methoxypoly(ethylene glycol) carbonate prodrugs of zidovudine and penetration through human skin in vitro.

  The Journal of pharmacy and pharmacology 20090601

• Grunwald-Winstein analysis: isopropyl chloroformate solvolysis revisited.

  International journal of molecular sciences 20090301

• Extended Grunwald-Winstein analysis - LFER used to gauge solvent effects in p-nitrophenyl chloroformate solvolysis.

  International journal of molecular sciences 20081101

• Affinity purification of natural ligands.

  Current protocols in protein science 20080501

• Bis(4-nitro-phen-yl) 1,3-phenyl-ene-dimethyl-ene dicarbonate.

  Acta crystallographica. Section E, Structure reports online 20080401

• 2,5-Dimethyl-hexane-2,5-diyl bis-(4-nitro-phen-yl) dicarbonate.

  Acta crystallographica. Section E, Structure reports online 20080401

• 4-Nitro-phenyl N-phenyl-carbamate.

  Acta crystallographica. Section E, Structure reports online 20080201

• trans-Cyclo-hex-2-ene-1,4-diyl bis-(4-nitro-phen-yl) dicarbonate.

  Acta crystallographica. Section E, Structure reports online 20080101

• trans-Cyclo-hexane-1,4-diyl bis-(4-nitro-phen-yl) dicarbonate.

  Acta crystallographica. Section E, Structure reports online 20080101

• The response of osteoblast-like cells towards collagen type I coating immobilized by p-nitrophenylchloroformate to titanium.

  Journal of biomedical materials research. Part A 20071201

• Addition of biological functionality to poly(epsilon-caprolactone) films.

  Biomacromolecules 20070801

• Rapidly in situ-forming degradable hydrogels from dextran thiols through Michael addition.

  Biomacromolecules 20070501

• cis-Tetrahydrofuran-3,4-diol structure as a key skeleton of new protecting groups removable by self-cyclization under oxidative conditions.

  The Journal of organic chemistry 20060929

• Temperature-sensitive pluronic/poly(ethylenimine) nanocapsules for thermally triggered disruption of intracellular endosomal compartment.

  Biomacromolecules 20060601

• Thermally reversible pluronic/heparin nanocapsules exhibiting 1000-fold volume transition.

  Langmuir : the ACS journal of surfaces and colloids 20060214

• Protein-functionalized polymer brushes.

  Biomacromolecules 20050101

• Strategies for covalent attachment of DNA to beads.

  Biopolymers 20040405

• Pharmacological properties of hydrophilic and lipophilic derivatives of octreotate.

  Nuclear medicine and biology 20040101

• Poly(ethylene glycol) prodrugs of the CDK inhibitor, alsterpaullone (NSC 705701): synthesis and pharmacokinetic studies.

  Bioconjugate chemistry 20040101

• Binding of D-mannose to poly(2-hydroxyethyl methacrylate) hydrogels by azo coupling.

  Biomaterials 20031001

• Organic reactions and nanoparticle preparation in CO(2)-induced water/P104/p-xylene microemulsions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030523

• PEGylation of G-CSF using cleavable oligo-lactic acid linkage.

  Journal of controlled release : official journal of the Controlled Release Society 20030429

• Affinity purification of natural ligands.

  Current protocols in protein science 20010501

• Biodegradable polymeric micelles composed of doxorubicin conjugated PLGA-PEG block copolymer.

  Journal of controlled release : official journal of the Controlled Release Society 20010129

• Synthesis and evaluation of prolyl carbamate nucleic acids (PrCNA).

  Nucleosides, nucleotides & nucleic acids 20010101

• Modification of oligo(poly(ethylene glycol) fumarate) macromer with a GRGD peptide for the preparation of functionalized polymer networks.

  Biomacromolecules 20010101