79794-75-5 | ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$6.00
5g	98%	in stock	$11.00	$8.00
10g	98%	in stock	$18.00	$13.00
100g	98%	in stock	$114.00	$80.00

Description

• Catalog Number: AI56551
• Chemical Name: ethyl 4-{13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene}piperidine-1-carboxylate
• CAS Number: 79794-75-5
• Molecular Formula: C22H23ClN2O2
• Molecular Weight: 382.8832
• MDL Number: MFCD00672869
• SMILES: CCOC(=O)N1CCC(=C2c3ccc(cc3CCc3c2nccc3)Cl)CC1

Computed Properties

• Complexity: 569
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 27
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• XLogP3: 5.2

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• Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa.

  Journal of pain research 20100101

• Clinical utility and patient adherence with ebastine for allergic rhinitis.

  Patient preference and adherence 20100101

• Hyperbaric oxygen ameliorates worsening signs and symptoms of post-traumatic stress disorder.

  Neuropsychiatric disease and treatment 20100101

• Aquagenic urticaria in 2 adolescents.

  Journal of investigational allergology & clinical immunology 20100101

• Update on the management of chronic eczema: new approaches and emerging treatment options.

  Clinical, cosmetic and investigational dermatology 20100101

• Design, Synthesis and Evaluation of Novel 1-(Substituted Acetyl)-4-(10-Bromo-8-Chloro-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridine-11-Ylidene)piperidines as Antitumor Agents and Farnesyl Protein Transferase Inhibitors.

  Indian journal of pharmaceutical sciences 20100101

• Safety of fixed-dose loratadine/montelukast in subjects with allergic rhinitis.

  Allergy and asthma proceedings 20100101

• Patent protection strategies.

  Journal of pharmacy & bioallied sciences 20100101

• Recent trends in the impurity profile of pharmaceuticals.

  Journal of advanced pharmaceutical technology & research 20100101

• A validated LC-MS/MS method for determination of sertaconazole nitrate in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

• [Gastric cancer].

  Nihon rinsho. Japanese journal of clinical medicine 20091201

• Rupatadine: pharmacological profile and its use in the treatment of allergic rhinitis.

  Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India 20091201

• Desloratadine inhibits human skin mast cell activation and histamine release.

  The Journal of investigative dermatology 20091101

• Desloratadine relieves nasal congestion and improves quality-of-life in persistent allergic rhinitis.

  Allergy 20091101

• Mast cell stabilizing properties of antihistamines.

  The Journal of investigative dermatology 20091101

• Clinical studies of combination montelukast and loratadine in patients with seasonal allergic rhinitis.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20091101

• Efficacy of desloratadine in intermittent allergic rhinitis: a GA(2)LEN study.

  Allergy 20091001

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• The basophil activation test in the diagnosis of allergy: technical issues and critical factors.

  Allergy 20090901

• Mast cells down-regulate CD4+CD25+ T regulatory cell suppressor function via histamine H1 receptor interaction.

  Journal of immunology (Baltimore, Md. : 1950) 20090901

• Desloratadine for the treatment of cypress pollen-induced allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090901

• Best drugs for what ails you: the brands to buy--and those to skip.

  Consumer reports 20090901

• Development of the loratadine gel for enhanced transdermal delivery.

  Drug development and industrial pharmacy 20090801

• Evidence for the contribution of tumour necrosis factor in oedema formation induced by histamine in the hind paw of the rat.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090801

• Parental attitudes toward new dosage forms of desloratadine in an online survey: results from four European countries.

  Current medical research and opinion 20090801

• Metabolism of loratadine and further characterization of its in vitro metabolites.

  Drug metabolism letters 20090801

• Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance.

  Current cardiology reviews 20090801

• An accurate-mass-based spectral-averaging isotope-pattern-filtering algorithm for extraction of drug metabolites possessing a distinct isotope pattern from LC-MS data.

  Analytical chemistry 20090715

• Evaluation of desloratadine on conjunctival allergen challenge-induced ocular symptoms.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090701

• The occurrence of antihistamines in sewage waters and in recipient rivers.

  Environmental science and pollution research international 20090701

• Safety of hookworm infection in individuals with measurable airway responsiveness: a randomized placebo-controlled feasibility study.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090701

• General unknown screening procedure for the characterization of human drug metabolites: Application to loratadine phase I metabolism.

  Journal of separation science 20090701

• Single-dose desloratadine and montelukast and allergen-induced late airway responses.

  The European respiratory journal 20090601

• Unsuspected polymorphic metabolism of rupatadine via its primary metabolite, desloratadine.

  Primary care respiratory journal : journal of the General Practice Airways Group 20090601

• A retention-time-shift-tolerant background subtraction and noise reduction algorithm (BgS-NoRA) for extraction of drug metabolites in liquid chromatography/mass spectrometry data from biological matrices.

  Rapid communications in mass spectrometry : RCM 20090601

• Costs of second-generation antihistamines in the treatment of allergic rhinitis: US perspective.

  Current medical research and opinion 20090601

• Desloratadine and pseudoephedrine combination therapy as a comprehensive treatment for allergic rhinitis and nasal congestion.

  Expert opinion on drug metabolism & toxicology 20090601

• A randomized study comparing the effect of loratadine added to montelukast with montelukast, loratadine, and beclomethasone monotherapies in patients with chronic asthma.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20090601

• Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090601

• Enhanced transdermal delivery of loratadine from the EVA matrix.

  Drug delivery 20090501

• A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.

  Clinical therapeutics 20090501

• Comparison of the efficacy of levocetirizine 5 mg and desloratadine 5 mg in chronic idiopathic urticaria patients.

  Allergy 20090401

• How to prescribe antihistamines for chronic idiopathic urticaria: desloratadine daily vs PRN and quality of life.

  Allergy 20090401

• Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus.

  The Journal of pharmacology and experimental therapeutics 20090401

• Multiple H1-antihistamine-induced urticaria.

  The Journal of dermatology 20090401

• Efficacy of loratadine-montelukast on nasal congestion in patients with seasonal allergic rhinitis in an environmental exposure unit.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090401

• The aggravatory effect of nicotine on Helicobacter pylori-induced gastric mucosa injury: role of asymmetric dimethylarginine.

  Journal of clinical gastroenterology 20090301

• Determination of pharmaceuticals in sewage sludge by pressurized liquid extraction (PLE) coupled to liquid chromatography-tandem mass spectrometry (LC-MS/MS).

  Analytical and bioanalytical chemistry 20090301

• High-dose desloratadine decreases wheal volume and improves cold provocation thresholds compared with standard-dose treatment in patients with acquired cold urticaria: a randomized, placebo-controlled, crossover study.

  The Journal of allergy and clinical immunology 20090301

• Effect of desloratadine on patients with allergic rhinitis and exercise-induced bronchoconstriction: a placebo controlled study.

  The Journal of asthma : official journal of the Association for the Care of Asthma 20090301

• Prevention of recurrent wheezing in young children by loratadine compared with ketotifen.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090301

• Safety and efficacy of desloratadine in chronic idiopathic urticaria in clinical practice: an observational study of 9246 patients.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090301

• Psychoactive medication and traffic safety.

  International journal of environmental research and public health 20090301

• Simultaneous determination of rupatadine and its metabolite desloratadine in human plasma by a sensitive LC-MS/MS method: application to the pharmacokinetic study in healthy Chinese volunteers.

  Journal of pharmaceutical and biomedical analysis 20090220

• Oral ulcerations caused by incorrect administration of desloratadine.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090201

• Structural characterization of in vitro rat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS.

  Journal of mass spectrometry : JMS 20090201

• Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment.

  Water research 20090201

• Acid-base equilibria and solubility of loratadine and desloratadine in water and micellar media.

  Journal of pharmaceutical and biomedical analysis 20090115

• Effects of loratadine/montelukast on vigilance and alertness task performance in a simulated cabin environment.

  Advances in therapy 20090101

• Comparison of the efficacy and safety of bilastine 20 mg vs desloratadine 5 mg in seasonal allergic rhinitis patients.

  Allergy 20090101

• Examining the tolerability of the non-sedating antihistamine desloratadine: a prescription-event monitoring study in England.

  Drug safety 20090101

• Systematic review on quality control for drug management programs: is quality reported in the literature?

  BMC health services research 20090101

• Quantitative determination of ticlopidine hydrochloride in human plasma by high-performance liquid chromatography-electronspray ionization mass spectrometry.

  Arzneimittel-Forschung 20090101

• Design, analysis, and presentation of crossover trials.

  Trials 20090101

• [Clinical research of Ibudilast on treating the steroid resistant allergic rhinitis].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20090101

• Efficacy and safety of desloratadine/pseudoephedrine combination vs its components in seasonal allergic rhinitis.

  Journal of investigational allergology & clinical immunology 20090101

• Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects.

  PloS one 20090101

• Efficacy and safety of fixed-dose loratadine/montelukast in seasonal allergic rhinitis: effects on nasal congestion.

  Allergy and asthma proceedings 20090101

• Onset of action of loratadine/montelukast in seasonal allergic rhinitis subjects exposed to ragweed pollen in the Environmental Exposure Unit.

  Allergy and asthma proceedings 20090101

• Effect of questionnaire structure on recall of drug utilization in a population of university students.

  BMC medical research methodology 20090101

• Management of allergic conjunctivitis: an evaluation of the perceived comfort and therapeutic efficacy of olopatadine 0.2% and azelastine 0.05% from two prospective studies.

  Clinical ophthalmology (Auckland, N.Z.) 20090101

• Etiologic aspects and prognostic factors of patients with chronic urticaria: nonrandomized, prospective, descriptive study.

  Journal of cutaneous medicine and surgery 20090101

• Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin.

  PloS one 20090101

• Loratadine and montelukast administered in combination produce decongestion in an experimental feline model of nasal congestion.

  American journal of rhinology & allergy 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Adrenocortical responsiveness to infusions of physiological doses of ACTH is not altered in posttraumatic stress disorder.

  Frontiers in behavioral neuroscience 20090101

• Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.

  Drugs 20090101

• Acute cough: a diagnostic and therapeutic challenge.

  Cough (London, England) 20090101

• Treating rhinitis in the older population: special considerations.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20090101

• H1-antihistamines and oxidative burst of professional phagocytes.

  Neuro endocrinology letters 20090101

• The anti-inflammatory effects of levocetirizine--are they clinically relevant or just an interesting additional effect?

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20090101

• Chronic urticaria and treatment options.

  Indian journal of dermatology 20090101

• Contact urticaria: present scenario.

  Indian journal of dermatology 20090101

• Management of difficult urticaria.

  Indian journal of dermatology 20090101

• Determination of Montelukast Sodium and Bambuterol Hydrochloride in Tablets using RP HPLC.

  Indian journal of pharmaceutical sciences 20090101

• A common but interesting case history.

  Journal of the Royal Naval Medical Service 20090101

• Leukotriene receptor antagonists in monotherapy or in combination with antihistamines in the treatment of chronic urticaria: a systematic review.

  Journal of asthma and allergy 20090101

• Once daily levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria.

  Journal of asthma and allergy 20090101

• Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines.

  Journal of asthma and allergy 20090101

• Exercise-induced asthma: critical analysis of the protective role of montelukast.

  Journal of asthma and allergy 20090101

• Patch tests with desloratadine at 10% induce false-positive results: test at 1%.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20081201

• Comparison of hydrophilic interaction and reversed-phase liquid chromatography coupled with tandem mass spectrometric detection for the determination of three pharmaceuticals in human plasma.

  Biomedical chromatography : BMC 20081201

• Ebastine in allergic rhinitis and chronic idiopathic urticaria.

  Allergy 20081201

• [Observation on cardiovascular safety of loratadine in treatment of persistent allergic rhinitis].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20081201

• [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081201

• Water-soluble loratadine inclusion complex: analytical control of the preparation by microwave irradiation.

  Journal of pharmaceutical and biomedical analysis 20081104

• Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

  Journal of medicinal chemistry 20081009

• Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis.

  Therapeutics and clinical risk management 20081001

• Miscellaneous.

  Indian journal of pharmacology 20081001

• Evaluation of efficacy and sedative profiles of H(1) antihistamines by large-scale surveillance using the visual analogue scale (VAS).

  Allergology international : official journal of the Japanese Society of Allergology 20080901

• Enhanced controlled release of loratadine from the ethylene-vinyl acetate matrix containing plasticizer.

  Drug delivery 20080901

• Pharmacokinetic and safety profile of rupatadine when coadministered with azithromycin at steady-state levels: a randomized, open-label, two-way, crossover, Phase I study.

  Clinical therapeutics 20080901

• Effect of allergic rhinitis on the use and cost of health services by children with asthma.

  Yonsei medical journal 20080830

• Antihistamine effects on experimental middle ear inflammatory model.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20080801

• [Clinical study on treatment of atopic dermatitis by integrated traditional Chinese and Western medicine].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20080801

• Surface degradation of composite resins by acidic medicines and pH-cycling.

  Journal of applied oral science : revista FOB 20080801

• Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. II. In vitro-in vivo correlation with ketoconazole.

  Drug metabolism and disposition: the biological fate of chemicals 20080701

• Circadian time-effect of orally administered loratadine on plasma pharmacokinetics in mice.

  Chronobiology international 20080701

• Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.

  Xenobiotica; the fate of foreign compounds in biological systems 20080701

• Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

  Journal of medicinal chemistry 20080612

• Quality of life in patients with facial steroid dermatitis before and after treatment.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080601

• Formulation and evaluation of oil entrapped gastroretentive floating gel beads of loratadine.

  Acta pharmaceutica (Zagreb, Croatia) 20080601

• Adherence with single-pill amlodipine/atorvastatin vs a two-pill regimen.

  Vascular health and risk management 20080601

• Treating common problems of the nose and throat in pregnancy: what is safe?

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20080501

• Nasal challenge with allergen leads to maxillary sinus inflammation.

  The Journal of allergy and clinical immunology 20080501

• [The effect of desloratadine on quality of life of patients with seasonal allergic rhinitis].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20080501

• A combination of statistical and analytical evaluation methods as a new optimization strategy for the quantification of pharmaceutical residues in sewage effluent.

  Analytica chimica acta 20080421

• Efficacy and safety of desloratadine combined with dipyridamole in the treatment of chronic urticaria.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080401

• Prospective randomized non-blinded clinical trial on the use of dapsone plus antihistamine vs. antihistamine in patients with chronic idiopathic urticaria.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080401

• Eosinophilic angiocentric fibrosis of the orbit.

  Clinical & experimental ophthalmology 20080401

• [The investigation of efficacy and safety of Aerius to seasonal allergic rhinitis].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20080401

• Efficacy of nasal corticosteroids alone or combined with antihistamines or montelukast in treatment of allergic rhinitis.

  Auris, nasus, larynx 20080301

• Loratadine during pregnancy and hypospadias.

  Epidemiology (Cambridge, Mass.) 20080301

• Drug treatments for skin disease introduced in 2007.

  Skin therapy letter 20080301

• Clinical benefits of combination treatment with mometasone furoate nasal spray and loratadine vs monotherapy with mometasone furoate in the treatment of seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080301

• Abnormal spirometry in children with persistent allergic rhinitis due to mite sensitization: the benefit of nasal corticosteroids.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20080201

• Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine.

  British journal of clinical pharmacology 20080201

• Treating common ear problems in pregnancy: what is safe?

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20080201

• Rasagiline in treatment of Parkinson's disease.

  Neuropsychiatric disease and treatment 20080201

• Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

  Journal of medicinal chemistry 20080124

• Quality of life in adults with chronic idiopathic urticaria receiving desloratadine: a randomized, double-blind, multicentre, placebo-controlled study.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20080101

• A new evaluation method for +Gz tolerance with loratadine by using a near-infrared spectroscopy.

  Dynamic medicine : DM 20080101

• Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.

  Clinical pharmacokinetics 20080101

• Effect of H1 antihistamines in a model of mesenteric ischaemia/reperfusion.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080101

• Interventions designed to improve the quality and efficiency of medication use in managed care: a critical review of the literature - 2001-2007.

  BMC health services research 20080101

• Behavioral conditioning of antihistamine effects in patients with allergic rhinitis.

  Psychotherapy and psychosomatics 20080101

• Chronic hypokalemia due to excessive cola consumption: a case report.

  Cases journal 20080101

• Clinical and biochemical effects of a combination botanical product (ClearGuard) for allergy: a pilot randomized double-blind placebo-controlled trial.

  Nutrition journal 20080101

• Risk of hypospadias in offspring of women using loratadine during pregnancy: a systematic review and meta-analysis.

  Drug safety 20080101

• Antihistaminic effects of rupatadine and PKPD modelling.

  European journal of drug metabolism and pharmacokinetics 20080101

• [Linear verrucous lesions of the trunk and limbs].

  Annales de dermatologie et de venereologie 20080101

• Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test.

  Indian journal of dermatology, venereology and leprology 20080101

• Late development of esophageal stricture following radiation and chemotherapy for small cell carcinoma of the lung: A case report.

  Cases journal 20080101

• Loratadine provides early symptom control in seasonal allergic rhinitis.

  Allergy and asthma proceedings 20080101

• Role of cytochrome P450 in drug interactions.

  Nutrition & metabolism 20080101

• Quality of life in patients with persistent allergic rhinitis treated with montelukast alone or in combination with levocetirizine or desloratadine.

  Journal of investigational allergology & clinical immunology 20080101

• Drug use in children: cohort study in three European countries.

  BMJ (Clinical research ed.) 20080101

• Type Ib indolent mastocytosis with systemic involvement: cutaneous mastocytosis and gastrointestinal involvement at young girl.

  Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 20080101

• Neurotrophins: are they meaningful in chronic spontaneous urticaria?

  Asian Pacific journal of allergy and immunology 20080101

• Efficacy of montelukast and loratadine as treatment for allergic rhinitis in children.

  Asian Pacific journal of allergy and immunology 20080101

• Dermatitis associated with exposure to a marine cyanobacterium during recreational water exposure.

  BMC dermatology 20080101

• Effects of roxithromycin on the pharmacokinetics of loratadine after oral and intravenous administration of loratadine in rats.

  European journal of drug metabolism and pharmacokinetics 20080101

• Staving off death: a case study of the pharmaceutical industry's strategies to protect blockbuster franchises.

  Food and drug law journal 20080101

• Passage-delaying microbeads for controlled delivery of loratadine.

  PDA journal of pharmaceutical science and technology 20080101

• High performance thin layer chromatographic method for simultaneous estimation of Ibuprofen and pseudoephedrine hydrochloride.

  Indian journal of pharmaceutical sciences 20080101

• Determination of ebastine in pharmaceutical formulations by HPLC.

  Indian journal of pharmaceutical sciences 20080101

• Fexofenadine hydrochloride in the treatment of allergic disease: a review.

  Journal of asthma and allergy 20080101

• Development and validation of high-throughput liquid chromatography-tandem mass spectrometric method for simultaneous quantification of loratadine and desloratadine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071215

• Rhinitis symptoms and quality of life in patients with chronic perennial rhinitis treated with desloratadine.

  The Journal of laryngology and otology 20071201

• Hybrid approach for the design of highly affine and selective dopamine D(3) receptor ligands using privileged scaffolds of biogenic amine GPCR ligands.

  Bioorganic & medicinal chemistry 20071201

• Determination of loratadine and pseudoephedrine sulfate in pharmaceuticals based on non-linear second-order spectrophotometric data generated by a pH-gradient flow injection technique and artificial neural networks.

  Analytical and bioanalytical chemistry 20071201

• Spectrophotometric, spectrofluorometric and HPLC determination of desloratadine in dosage forms and human plasma.

  Chemical & pharmaceutical bulletin 20071201

• Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet [20 mg] versus desloratadine capsule [5 mg]: a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adults.

  Clinical therapeutics 20071201

• Simultaneous determination of desloratadine and its active metabolite 3-hydroxydesloratadine in human plasma by LC/MS/MS and its application to pharmacokinetics and bioequivalence.

  Journal of pharmaceutical and biomedical analysis 20071130

• Desloratadine improves quality of life and symptom severity in patients with allergic rhinitis.

  Allergy 20071101

• Validated ion pair liquid chromatography/fluorescence detection method for assessing the variability of the loratadine metabolism occurring in bioequivalence studies.

  Biomedical chromatography : BMC 20071001

• Microwave non-destructive testing technique for characterization of HPMC-PEG 3000 films.

  International journal of pharmaceutics 20071001

• Multiple-dose pharmacokinetics and safety of desloratadine in subjects with moderate hepatic impairment.

  Journal of clinical pharmacology 20071001

• A randomized, double-blind, parallel-group study to compare the efficacy and safety of a once-daily loratadine-pseudoephedrine combination with that of a twice-daily loratadine-pseudoephedrine combination in the treatment of allergic rhinitis.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20070901

• In vitro detection of drug-induced phospholipidosis using gene expression and fluorescent phospholipid based methodologies.

  Toxicological sciences : an official journal of the Society of Toxicology 20070901

• Desloratadine treatment for intermittent and persistent allergic rhinitis: a review.

  Clinical therapeutics 20070901

• [Cardiac safety evaluation of loratadine in the treatment of allergic rhinitis in elderly patients].

  Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20070901

• Desloratadine dose selection in children aged 6 months to 2 years: comparison of population pharmacokinetics between children and adults.

  British journal of clinical pharmacology 20070801

• Interaction of loratadine with serum albumins studied by fluorescence quenching method.

  Journal of biochemical and biophysical methods 20070801

• The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease.

  Pharmacology & therapeutics 20070801

• Determination of loratadine and its active metabolite in human plasma by high-performance liquid chromatography with mass spectrometry detection.

  Journal of pharmaceutical and biomedical analysis 20070727

• Disposition of loratadine in healthy volunteers.

  Xenobiotica; the fate of foreign compounds in biological systems 20070701

• Disposition of desloratadine in healthy volunteers.

  Xenobiotica; the fate of foreign compounds in biological systems 20070701

• A simple and reliable procedure for the determination of psychoactive drugs in oral fluid by gas chromatography-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20070628

• Validated liquid chromatographic-ultraviolet method for the quantitation of tadalafil in human plasma using liquid-liquid extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

• The effect of regular versus on-demand desloratadine treatment in children with allergic rhinitis.

  International journal of pediatric otorhinolaryngology 20070601

• Montelukast decreased exhaled nitric oxide in children with perennial allergic rhinitis.

  Pediatrics international : official journal of the Japan Pediatric Society 20070601

• [New generation antihistamines as monotherapy or in combination. What is the relevance for daily clinical routine for allergic rhinoconjunctivitis].

  HNO 20070601

• [Clinical observation on pricking and blood-letting and cupping with a three-edge needle for treatment of acute eczema].

  Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20070601

• A gero-informatics tool to enhance the care of hospitalized older adults with cognitive impairment.

  Clinical interventions in aging 20070601

• Montelukast in the management of allergic rhinitis.

  Therapeutics and clinical risk management 20070601

• Study of tanshinone IIA tissue distribution in rat by liquid chromatography-tandem mass spectrometry method.

  Biomedical chromatography : BMC 20070501

• Cost-effectiveness of grass allergen tablet (GRAZAX) for the prevention of seasonal grass pollen induced rhinoconjunctivitis - a Northern European perspective.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20070501

• Pharmacokinetics of desloratadine in children between 2 and 11 years of age.

  British journal of clinical pharmacology 20070501

• Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet (20 mg) versus desloratadine capsule (5 mg): a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adults.

  Clinical therapeutics 20070501

• Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study.

  Clinical therapeutics 20070501

• Quantitative determination of donepezil in human plasma by liquid chromatography/tandem mass spectrometry employing an automated liquid-liquid extraction based on 96-well format plates. Application to a bioequivalence study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

• The nose - from symptoms to evidence-based medicine.

  Allergy 20070401

• Efficacy of desloratadine in the treatment of allergic rhinitis: a meta-analysis of randomized, double-blind, controlled trials.

  Allergy 20070401

• Review of azelastine nasal spray in the treatment of allergic and non-allergic rhinitis.

  Expert opinion on pharmacotherapy 20070401

• An open-label, investigator-masked, crossover study of the ocular drying effects of two antihistamines, topical epinastine and systemic loratadine, in adult volunteers with seasonal allergic conjunctivitis.

  Clinical therapeutics 20070401

• Further studies on the mechanism of antiphagocyte-antioxidative effect of H1-antihistamines.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401

• Simultaneous determination of loratadine and desloratadine in pharmaceutical preparations using liquid chromatography with a microemulsion as eluent.

  Journal of pharmaceutical and biomedical analysis 20070312

• Once-daily sublingual allergen-specific immunotherapy improves quality of life in patients with grass pollen-induced allergic rhinoconjunctivitis: a double-blind, randomised study.

  Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20070301

• Evaluating drug prices, availability, affordability, and price components: implications for access to drugs in Malaysia.

  PLoS medicine 20070301

• Effectiveness of desloratadine 5 mg once daily in patients with symptoms of seasonal allergic rhinitis: results of a Canadian multicenter, open-label trial.

  Clinical therapeutics 20070301

• Degradation product of loratadine.

  Journal of pharmaceutical and biomedical analysis 20070219

• Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor.

  Analytical and bioanalytical chemistry 20070201

• Assessment of the first and second generation antihistamines brain penetration and role of P-glycoprotein.

  Pharmaceutical research 20070201

• Effects of desloratadine and alcohol coadministration on psychomotor performance.

  Current medical research and opinion 20070201

• Quantitative determination of galantamine in human plasma by sensitive liquid chromatography-tandem mass spectrometry using loratadine as an internal standard.

  Journal of chromatographic science 20070201

• Characterization of hydroxypropylmethylcellulose films using microwave non-destructive testing technique.

  Journal of pharmaceutical and biomedical analysis 20070117

• The effect of montelukast (10mg daily) and loratadine (10mg daily) on wheal, flare and itching reactions in skin prick tests.

  Pulmonary pharmacology & therapeutics 20070101

• The effect of 4 weeks treatment with desloratadine (5mg daily) on levels of interleukin (IL)-4, IL-10, IL-18 and TGF beta in patients suffering from seasonal allergic rhinitis.

  Pulmonary pharmacology & therapeutics 20070101

• A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome p450 phenotypic data.

  Drug metabolism and disposition: the biological fate of chemicals 20070101

• Efficacy and safety of desloratadine in adults with chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, multicenter trial.

  American journal of clinical dermatology 20070101

• Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.

  Journal of investigational allergology & clinical immunology 20070101

• Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare.

  Allergy and asthma proceedings 20070101

• Montelukast in the treatment of allergic rhinitis: an evidence-based review.

  Drugs 20070101

• A sensitive spectrophotometric method for the determination of desloratadine in tablets.

  Journal of AOAC International 20070101

• Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum.

  Journal of AOAC International 20070101

• Premedication with montelukast reduces local reactions of allergen immunotherapy.

  International archives of allergy and immunology 20070101

• [Peripheral anticholinergic syndrome].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20070101

• A comparison of ebastine 10 mg fast-dissolving tablet with oral desloratadine and placebo in inhibiting the cutaneous reaction to histamine in healthy adults.

  Clinical drug investigation 20070101

• Simultaneous determination of desloratadine and pseudoephedrine in human plasma using micro solid-phase extraction tips and aqueous normal-phase liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• [Effects of methimazole on the evolution of the allergic rhinitis of patients with Graves' disease].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20070101

• Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review.

  Allergy and asthma proceedings 20070101

• Desloratadine for chronic idiopathic urticaria: a review of clinical efficacy.

  American journal of clinical dermatology 20070101

• The non-destructive identification of solid over-the-counter medications using single particle aerosol mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Eosinophil recruiting chemokines are down-regulated in peripheral blood mononuclear cells of allergic patients treated with deflazacort or desloratadine.

  International journal of immunopathology and pharmacology 20070101

• Ranitidine (150 mg daily) inhibits wheal, flare, and itching reactions in skin-prick tests.

  Allergy and asthma proceedings 20070101

• Verapamil, but not probenecid, co-administration can convert desloratadine to a sedating antihistamine in mice.

  Drug metabolism letters 20070101

• Progress and challenges in the understanding of chronic urticaria.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20070101

• Desloratadine in combination with montelukast suppresses the dermographometer challenge test papule, and is effective in the treatment of delayed pressure urticaria: a randomized, double-blind, placebo-controlled study.

  The British journal of dermatology 20061201

• Extra- and intracellular formation of reactive oxygen species by human neutrophils in the presence of pheniramine, chlorpheniramine and brompheniramine.

  Neuro endocrinology letters 20061201

• On the pharmacology and toxicology of neutrophils.

  Neuro endocrinology letters 20061201

• [Cronkhite-Canada syndrome: an acquired, potentially reversible polyposis].

  Gastroenterologia y hepatologia 20061201

• Solid lipid microparticles containing loratadine prepared using a Micromixer.

  Journal of microencapsulation 20061201

• The CML-related oncoprotein BCR/ABL induces expression of histidine decarboxylase (HDC) and the synthesis of histamine in leukemic cells.

  Blood 20061115

• Re: loratadine exerts estrogen-like effects and disrupts penile development in the mouse.

  The Journal of urology 20061101

• New antihistamines: a critical view.

  Jornal de pediatria 20061101

• Montelukast with desloratadine or levocetirizine for the treatment of persistent allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101

• [Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101

• [The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101

• Vanished behind the counter. Starting this week, you'll need help buying your claritin and nyquil.

  U.S. news & world report 20061002

• Henna tattooing dermatitis: consider an additive as the culprit.

  The British journal of general practice : the journal of the Royal College of General Practitioners 20061001

• Roxithromycin induced hypersensitivity pneumonitis.

  Pathology 20061001

• Cutaneous mastocytosis in a patient with primary Sjögren's syndrome.

  The Journal of rheumatology 20060801

• Multiple daily administrations of low-dose sublingual immunotherapy in allergic rhinoconjunctivitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060801

• Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis.

  Molecular carcinogenesis 20060701

• Spontaneous scratching behaviour in DS-Nh mice as a possible model for pruritus in atopic dermatitis.

  Immunology 20060701

• Diphenhydramine vs desloratadine comparisons must consider risk-benefit ratio.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701

• Development and validation of a sensitive liquid chromatography/electrospray tandem mass spectrometry assay for the quantification of olanzapine in human plasma.

  Journal of pharmaceutical and biomedical analysis 20060607

• Form I of desloratadine, a tricyclic antihistamine.

  Acta crystallographica. Section C, Crystal structure communications 20060601

• The relative bioavailability of loratadine administered as a chewing gum formulation in healthy volunteers.

  European journal of clinical pharmacology 20060601

• Do the leukotriene receptor antagonists work in children with grass pollen-induced allergic rhinitis?

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20060601

• Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060601

• Influence of cetirizine and loratadine on granulocyte-macrophage colony-stimulating factor and interleukin-8 release in A549 human airway epithelial cells stimulated with interleukin-1beta.

  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20060601

• Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.

  Southern medical journal 20060601

• Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060601

• A comparison of levocetirizine and desloratadine in the histamine-induced wheal and flare response in human skin in vivo.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060601

• Optimization by factorial design of a capillary zone electrophoresis method for the simultaneous separation of antihistamines.

  Analytical biochemistry 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Erosive effect of an antihistamine-containing syrup on primary enamel and its reduction by fluoride dentifrice.

  International journal of paediatric dentistry 20060501

• Genotypic characterization of Helicobacter pylori cagA and vacA from biopsy specimens of patients with gastroduodenal diseases.

  The Mount Sinai journal of medicine, New York 20060501

• [Comparison of clinical efficacy and cost-quality of antihistamines in early treatment for Japanese cedar pollinosis].

  Arerugi = [Allergy] 20060501

• Efficacy of a leukotriene receptor antagonist in the treatment of perennial allergic rhinitis.

  The Journal of otolaryngology 20060401

• H(1)- antihistamines and activated blood platelets.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• Extra- and intracellular oxidant production in phorbol myristate acetate stimulated human polymorphonuclear leukocytes: modulation by histamine and H(1)-antagonist loratadine.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401

• Influence of desloratadine on oxidative stress markers in patients with chronic idiopathic urticaria.

  International journal of dermatology 20060401

• Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401

• Comparative evaluation of HERG currents and QT intervals following challenge with suspected torsadogenic and nontorsadogenic drugs.

  The Journal of pharmacology and experimental therapeutics 20060301

• Adult and paediatric poor metabolisers of desloratadine: an assessment of pharmacokinetics and safety.

  Expert opinion on drug safety 20060301

• Desloratadine 5 mg once daily improves the quality of life of patients with chronic idiopathic urticaria.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060301

• Evaluation of product switching after a state Medicaid program began covering loratadine OTC 1 year after market availability.

  Journal of managed care pharmacy : JMCP 20060301

• What are the public health effects of direct-to-consumer drug advertising?

  PLoS medicine 20060301

• Porous polystyrene beads as carriers for self-emulsifying system containing loratadine.

  AAPS PharmSciTech 20060301

• Desloratadine therapy for symptoms associated with perennial allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060301

• [Inhibitory effects of mizolastine on substance P-induced production of leukotriene B4 and interleukin 5 in mouse skin].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060301

• Orthogonal extraction/chromatography and UPLC, two powerful new techniques for bioanalytical quantitation of desloratadine and 3-hydroxydesloratadine at 25 pg/mL.

  Journal of pharmaceutical and biomedical analysis 20060224

• Loratadine exerts estrogen-like effects and disrupts penile development in the mouse.

  The Journal of urology 20060201

• Formalin injection into knee joints of rats: pharmacologic characterization of a deep somatic nociceptive model.

  The journal of pain : official journal of the American Pain Society 20060201

• Effect of desloratadine therapy on symptom scores and measures of nasal patency in seasonal allergic rhinitis: results of a single-center, placebo-controlled trial.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060201

• How does exercise cause asthma attacks?

  Current opinion in allergy and clinical immunology 20060201

• Effect of desloratadine on epithelial cell granulocyte-macrophage colony-stimulating factor secretion and eosinophil survival.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060101

• Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy.

  Current medical research and opinion 20060101

• Angioedema and urticaria due to isotretinoin therapy.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20060101

• Vitamin E effects on nasal symptoms and serum specific IgE levels in patients with perennial allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060101

• [Clinical effect of treatment for clearing heat, detoxicating and nourishing Yin on patients with glucocorticosteroid induced facial dermatitis and its effect on skin barrier function].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060101

• Bioavailability of two oral formulations of loratadine 20 mg with concomitant ketoconazole: an open-label, randomized, two-period crossover comparison in healthy Mexican adult volunteers.

  Clinical therapeutics 20060101

• A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis.

  Clinical therapeutics 20060101

• Morphology evaluation of primary enamel exposed to antihistamine and fluoride dentifrice--an in vitro study.

  General dentistry 20060101

• Serum sickness-like reaction associated with cefazolin.

  BMC clinical pharmacology 20060101

• Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals.

  BMC cell biology 20060101

• Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring.

  International journal of medical sciences 20060101

• Levocetirizine: a review of its use in the management of allergic rhinitis and skin allergies.

  Drugs 20060101

• Impact of desloratadine and loratadine on the crosstalk between human keratinocytes and leukocytes: Implications for anti-inflammatory activity of antihistamines.

  International archives of allergy and immunology 20060101

• Immunotherapy for patients with persistent allergic rhinitis unsatisfied with free chronic pharmacotherapy.

  Allergologia et immunopathologia 20060101

• No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy.

  International journal of medical sciences 20060101

• The combined luminol/isoluminol chemiluminescence method for differentiating between extracellular and intracellular oxidant production by neutrophils.

  Redox report : communications in free radical research 20060101

• Prenatal exposure to loratadine in children with hypospadias: a nested case-control study within the Danish National Birth Cohort.

  American journal of therapeutics 20060101

• Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis.

  Allergy and asthma proceedings 20060101

• Is the usage of intranasal glucocorticosteroids alone in allergic rhinitis sufficient?

  Allergy and asthma proceedings 20060101

• Saliva secretion in patients with allergic rhinitis.

  International archives of allergy and immunology 20060101

• Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.

  The European journal of general practice 20060101

• Gangliocytes in neuroblastic tumors express alarin, a novel peptide derived by differential splicing of the galanin-like peptide gene.

  Journal of molecular neuroscience : MN 20060101

• Fever with rash following zolendronic acid administration.

  Clinical and experimental rheumatology 20060101

• Comparison of the risk of drowsiness and sedation between levocetirizine and desloratadine: a prescription-event monitoring study in England.

  Drug safety 20060101

• New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.

  Pharmacology 20060101

• Treatment in the pediatric emergency department is evidence based: a retrospective analysis.

  BMC pediatrics 20060101

• Desorption electrospray ionization using an Orbitrap mass spectrometer: Exact mass measurements on drugs and peptides.

  Rapid communications in mass spectrometry : RCM 20060101

• A randomized controlled trial of cetirizine plus pseudoephedrine versus loratadine plus pseudoephedrine for perennial allergic rhinitis.

  Asian Pacific journal of allergy and immunology 20060101

• Effect of desloratadine on the control of morning symptoms in patients with seasonal and perennial allergic rhinitis.

  Allergy and asthma proceedings 20060101

• Selecting the optimal oral antihistamine for patients with allergic rhinitis.

  Drugs 20060101

• Emedastine difumarate versus loratadine in chronic idiopathic urticaria: a randomized, double-blind, controlled European multicentre clinical trial.

  European journal of dermatology : EJD 20060101

• Effect of olopatadine and other histamine H1 receptor antagonists on the skin inflammation induced by repeated topical application of oxazolone in mice.

  Pharmacology 20051201

• Meta-analysis of the efficacy of ebastine 20 mg compared to loratadine 10 mg and placebo in the symptomatic treatment of seasonal allergic rhinitis.

  International archives of allergy and immunology 20051201

• Desloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennial allergic rhinitis: a pilot study.

  International immunopharmacology 20051201

• Treatment for allergic rhinitis and chronic idiopathic urticaria: focus on oral antihistamines.

  The Annals of pharmacotherapy 20051201

• Non-antibiotic treatments for upper-respiratory tract infections (common cold).

  Respiratory medicine 20051201

• Sexual dysfunction in patients with allergic rhinoconjunctivitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051201

• Management of persistent allergic rhinitis: evidence-based treatment with levocetirizine.

  Therapeutics and clinical risk management 20051201

• The effects of olopatadine hydrochloride on the number of scratching induced by repeated application of oxazolone in mice.

  European journal of pharmacology 20051107

• The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study.

  International archives of allergy and immunology 20051101

• Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders.

  Expert opinion on pharmacotherapy 20051101

• Spectrofluorometric determination of montelukast in dosage forms and spiked human plasma.

  Die Pharmazie 20051101

• [Isotachophoretic determination of desloratadine in tablets and syrup].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20051101

• Efficacy of intramuscular BCG polysaccharide nucleotide on mild to moderate bronchial asthma accompanied with allergic rhinitis: a randomized, double blind, placebo-controlled study.

  Chinese medical journal 20051005

• Desloratadine reduces systemic allergic inflammation following nasal provocation in allergic rhinitis and asthma patients.

  Allergy 20051001

• Effect of combined montelukast and desloratadine on the early asthmatic response to inhaled allergen.

  The Journal of allergy and clinical immunology 20051001

• Acute bacterial rhinosinusitis causes hyperresponsiveness to histamine challenge in mice.

  Archives of otolaryngology--head & neck surgery 20051001

• Treatment of ear pain in pilots in flight.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051001

• Inflammatory basis of exercise-induced bronchoconstriction.

  American journal of respiratory and critical care medicine 20050915

• Effect of cyp2d6*10 allele on the pharmacokinetics of loratadine in chinese subjects.

  Drug metabolism and disposition: the biological fate of chemicals 20050901

• Simultaneous determination of loratadine and pseudoephedrine sulfate in human plasma by liquid chromatography-electrospray mass spectrometry for pharmacokinetic studies.

  Journal of pharmaceutical and biomedical analysis 20050901

• L-selectin expression on neutrophils from allergic patients.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20050901

• Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.

  Current medical research and opinion 20050901

• Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901

• Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro.

  Mediators of inflammation 20050814

• Histamine helps development of eczematous lesions in experimental contact dermatitis in mice.

  Archives of dermatological research 20050801

• Off-label prescribing to children: attitudes and experience of general practitioners.

  British journal of clinical pharmacology 20050801

• Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.

  Journal of the American Academy of Nurse Practitioners 20050801

• [Desloratadine for chronic idiopathic urticaria].

  Harefuah 20050801

• Medical treatment for rhinosinusitis associated with adenoidal hypertrophy in children: an evaluation of clinical response and changes on magnetic resonance imaging.

  The Annals of otology, rhinology, and laryngology 20050801

• Review of H1 antihistamines in the treatment of chronic idiopathic urticaria.

  Cutis 20050801

• Spray-dried chitosan/ethylcellulose microspheres for nasal drug delivery: swelling study and evaluation of in vitro drug release properties.

  Journal of microencapsulation 20050801

• Effect of loratadine on mouse models of atopic dermatitis associated pruritus.

  International immunopharmacology 20050701

• Collection of medical drug information in pharmacies: Drug Event Monitoring (DEM) in Japan.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050701

• [Study on determination of desloratadine in human serum and its pharmacokinetics by HPLC/MS].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20050701

• A new HPLC approach for the determination of hydrophilic and hydrophobic components: the case of pseudoephedrine sulfate and loratadine in tablets.

  Drug development and industrial pharmacy 20050701

• [Effect of humectants on pharmaceutical availability and rheological properties of loratadine-containing hydrogels].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20050701

• A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis.

  Clinical therapeutics 20050701

• Acute cholestasis related to desloratidine.

  World journal of gastroenterology 20050621

• Determination of desloratadine in drug substance and pharmaceutical preparations by liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20050615

• An open-label series using loratadine for the treatment of sexual dysfunction associated with selective serotonin reuptake inhibitors.

  Progress in neuro-psychopharmacology & biological psychiatry 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• The effect of the Rx-to-OTC switch of loratadine and changes in prescription drug benefits on utilization and cost of therapy.

  The American journal of managed care 20050601

• Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

  Journal of medicinal chemistry 20050505

• Cannabinoids, loratadine and allopurinol as novel additions to the antipsoriatic ammunition.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20050501

• [Pre-formulation studies of the H1-antihistamine loratadine for a topical dosage form].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20050501

• Switching prescription drugs to over the counter: consumers may benefit financially in examples from the US.

  BMJ (Clinical research ed.) 20050416

• The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050401

• Antiplatelet and antiphagocyte activity of H1-antihistamines.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050401

• [The effect of antianaphylaxis drugs on specific IgE and eosinophil in serum of patients with allergic rhinitis].

  Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050401

• [The effect of desloratadine on the TXB2 and leukotrienes levels in the nasal lavage fluid of allergic rhinitis animal model].

  Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050401

• Norpiperidine imidazoazepines as a new class of potent, selective, and nonsedative H1 antihistamines.

  Journal of medicinal chemistry 20050324

• Development and bioadhesive properties of chitosan-ethylcellulose microspheres for nasal delivery.

  International journal of pharmaceutics 20050303

• Evidence of desloratadine syrup efficacy and tolerability in children with pollen-induced allergic rhinitis.

  Allergy 20050301

• The effect of mizolastine on expression of vascular endothelial cell growth factor, tumour necrosis factor-alpha and keratinocyte-derived chemokine in murine mast cells, compared with dexamethasone and loratadine.

  Clinical and experimental dermatology 20050301

• Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects.

  British journal of clinical pharmacology 20050301

• Increased nasal airflow with budesonide compared with desloratadine during the allergy season.

  Archives of otolaryngology--head & neck surgery 20050301

• Torsade de pointes in patients on chronic amiodarone treatment: contributing factors and drug interactions.

  The Israel Medical Association journal : IMAJ 20050301

• Efficacy and safety of an extended-release formulation of desloratadine and pseudoephedrine vs the individual components in the treatment of seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050301

• [The immunohistochemical observations of NOS in the nasal mucosa of allergic rhinitis animal model of guinea pigs].

  Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050301

• The cold-pill crackdown.

  Time 20050207

• A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system.

  Toxicological sciences : an official journal of the Society of Toxicology 20050201

• Metabolism and excretion of loratadine in male and female mice, rats and monkeys.

  Xenobiotica; the fate of foreign compounds in biological systems 20050201

• [Effects of budesonide, desloratadine and dexamethasone on interleukine-4 release and expression from human mast cell line].

  Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20050201

• [The effect of desloratadine on use of rescue beta2-agonists and symptoms in patients suffering from seasonal allergic rhinitis and asthma].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050201

• [The influence of desloratadine on course of intermittens allergic rhinitis].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050201

• Stability studies on some benzocycloheptane antihistaminic agents.

  Journal of pharmaceutical and biomedical analysis 20050104

• The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model.

  Drug metabolism and disposition: the biological fate of chemicals 20050101

• Inhibition of nasal polyp mast cell and eosinophil activation by desloratadine.

  Allergy 20050101

• Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique.

  Allergy 20050101

• Examination of 209 drugs for inhibition of cytochrome P450 2C8.

  Journal of clinical pharmacology 20050101

• Switching prescription drugs to over the counter.

  BMJ (Clinical research ed.) 20050101

• Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitis.

  Drugs 20050101

• [Oral second generation antihistamines in allergic rhinitis].

  Laryngo- rhino- otologie 20050101

• South Dakota Medicaid will now cover OTC Loratadine and OTC Prilosec.

  South Dakota journal of medicine 20050101

• OTC product: Loratadine for urticaria.

  Journal of the American Pharmacists Association : JAPhA 20050101

• Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport.

  BMC pharmacology 20050101

• [Preliminary clinical study of fubiding in treatment of perennial allergic rhinitis].

  Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050101

• Heal the damage: prescription drug consumer advertisements and relative choices.

  Journal of health law 20050101

• Fetal safety of drugs used in the treatment of allergic rhinitis: a critical review.

  Drug safety 20050101

• Circadian time-dependent differences in murine tolerance to the antihistaminic agent loratadine.

  Chronobiology international 20050101

• Cost and utilization impacts of oral antihistamines in the California Medi-Cal program.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101

• In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine.

  BMC pharmacology 20050101

• [Therapeutic options in idiopathic chronic urticaria].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20050101

• [Nasal budesonide plus zafirlukast vs nasal budesonide plus loratadine-pseudoephedrine for controlling the symptoms of rhinitis and asthma].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20050101

• [Montelukast: new therapeutic option in patients with nasal polyps associated to respiratory allergic disease].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20050101

• Severe anaphylactic reaction during the second infusion of infliximab in a patient with psoriatic arthritis.

  Allergologia et immunopathologia 20050101

• The safety and efficacy of desloratadine for the management of allergic disease.

  Drug safety 20050101

• Montelukast effectively treats the nighttime impact of seasonal allergic rhinitis.

  American journal of rhinology 20050101

• Efficacy and safety of desloratadine/pseudoephedrine tablet, 2.5/120 mg two times a day, versus individual components in the treatment of patients with seasonal allergic rhinitis.

  Allergy and asthma proceedings 20050101

• Case studies: Use of salicylic acid (Avosil) and hydrogel (Avogel) in limiting scar formation.

  Journal of burns and wounds 20050101

• Synthesis and structure-activity relationships of novel histamine H1 antagonists: indolylpiperidinyl benzoic acid derivatives.

  Journal of medicinal chemistry 20041202

• Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor.

  International archives of allergy and immunology 20041201

• Loratidine improves ischemic parameters of exercise stress test in patients with acute myocardial infarction.

  American heart journal 20041201

• Inhibitory effects of budesonide, desloratadine and dexamethasone on cytokine release from human mast cell line (HMC-1).

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20041201

• [Comparative activity of antihistamines on area under dose-response curve from histamine-induced wheal and flare responses in human skin].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20041201

• Safety of desloratadine syrup in children.

  Current medical research and opinion 20041201

• Development of modified-release dosage forms containing loratadine and pseudoephedrine sulfate.

  Acta poloniae pharmaceutica 20041201

• State and trait anxiety in patients affected by nasal polyposis before and after medical treatment.

  Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 20041201

• Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity.

  Bioorganic & medicinal chemistry letters 20041115

• Pharmacokinetics/pharmacodynamics of desloratadine and fluoxetine in healthy volunteers.

  Journal of clinical pharmacology 20041101

• Homology modelling and binding site mapping of the human histamine H1 receptor.

  European journal of medicinal chemistry 20041101

• Gallbladder vasculitis associated with cutaneous leucocytoclastic vasculitis.

  The Australasian journal of dermatology 20041101

• [Clinical effect of escin on patients with cutaneous pruritus caused by blood stasis and wind-dryness].

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20041101

• Prophylactic management of children at risk for recurrent upper respiratory infections: the Preventia I Study.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041101

• An evaluation of the ocular drying effects of 2 systemic antihistamines: loratadine and cetirizine hydrochloride.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041101

• Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.

  Journal of cardiovascular electrophysiology 20041101

• To evaluate and compare the effects of first generation anti-histamine (chlorpheniramine maleate) and second generation anti-histamine (loratadine) on isolated trachea of rabbit.

  JPMA. The Journal of the Pakistan Medical Association 20041101

• Current concepts and therapeutic strategies for allergic rhinitis in school-age children.

  Clinical therapeutics 20041101

• Rapid determination of loratadine in small volume plasma samples by high-performance liquid chromatography with fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041005

• Comparison of the effects in the nose and skin of a single dose of desloratadine and levocetirizine over 24 hours.

  International archives of allergy and immunology 20041001

• Classification of loratadine based on the biopharmaceutics drug classification concept and possible in vitro-in vivo correlation.

  Biological & pharmaceutical bulletin 20041001

• Desloratadine partially inhibits the augmented bacterial responses in the sinuses of allergic and infected mice.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041001

• Coseasonal sublingual immunotherapy reduces the development of asthma in children with allergic rhinoconjunctivitis.

  The Journal of allergy and clinical immunology 20041001

• Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine.

  Biopharmaceutics & drug disposition 20040901

• Anti-inflammatory properties of desloratadine.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901

• Desloratadine in combination with montelukast in the treatment of chronic urticaria: a randomized, double-blind, placebo-controlled study.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901

• Randomized placebo-controlled trial comparing desloratadine and montelukast in monotherapy and desloratadine plus montelukast in combined therapy for chronic idiopathic urticaria.

  The Journal of allergy and clinical immunology 20040901

• Modern histamine H1-receptor antagonists in the unified airway.

  The Journal of allergy and clinical immunology 20040901

• Does hormone therapy increase allergic reactions and upper gastrointestinal problems? Results from a population-based study of Swedish woman. The women's health in the Lund area (WHILA) study.

  Maturitas 20040820

• Antihistamines: do they work? Further well-controlled trials involving larger samples are needed.

  Allergy 20040801

• A review of the second-generation antihistamine ebastine for the treatment of allergic disorders.

  Expert opinion on pharmacotherapy 20040801

• Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.

  Fundamental & clinical pharmacology 20040801

• A validated HPLC-ESI-MS method for the determination of loratadine in human plasma and its application to pharmacokinetic studies.

  Die Pharmazie 20040801

• [Clinical examination of mizolastine in the seasonal allergic rhinitis].

  Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20040801

• [Nasal obstruction on the decline. Antihistamine allows allergic patients to breathe].

  MMW Fortschritte der Medizin 20040708

• Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements.

  European journal of clinical pharmacology 20040701

• Tolerance induction to rofecoxib in a patient with Bartter's syndrome.

  Allergy 20040701

• Oral administration of desloratadine prior to sensitization prevents allergen-induced airway inflammation and hyper-reactivity in mice.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040701

• Nasal saline: placebo or drug?

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040701

• [Analysis of tablets containing the antihistamine loratadine: a contribution to the identification of impurities].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20040701

• Effect of perinatal (prenatal?) loratadine exposure on male rat reproductive organ development.

  Reproductive toxicology (Elmsford, N.Y.) 20040601

• Treatment with intranasal fluticasone propionate significantly improves ocular symptoms in patients with seasonal allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040601

• Levocetirizine improves nasal obstruction and modulates cytokine pattern in patients with seasonal allergic rhinitis: a pilot study.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040601

• A direct comparison of the efficacy of antihistamines in SAR and PAR: randomised, placebo-controlled studies with levocetirizine and loratadine using an environmental exposure unit - the Vienna Challenge Chamber (VCC).

  Current medical research and opinion 20040601

• Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040601

• [Combination therapy of allergic rhinitis. So that from hay fever asthma won't come].

  MMW Fortschritte der Medizin 20040527

• Desloratadine shows no effect on performance during 6 h at 8,000 ft simulated cabin altitude.

  Aviation, space, and environmental medicine 20040501

• Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040501

• [Not a minor illness. Hay fever therapy should not be left to the patient].

  MMW Fortschritte der Medizin 20040408

• Preparation and coating of finely dispersed drugs 4. Loratadine and danazol.

  Journal of colloid and interface science 20040401

• Improvements in simulated real-world relevant performance for patients with seasonal allergic rhinitis: impact of desloratadine.

  Allergy 20040401

• Efficacy and safety of ebastine 20 mg compared to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled study.

  International archives of allergy and immunology 20040401

• Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401

• Advances in upper airway diseases and allergen immunotherapy.

  The Journal of allergy and clinical immunology 20040401

• Levocetirizine better protects than desloratadine in a nasal provocation with allergen.

  The Journal of allergy and clinical immunology 20040401

• Capillary zone electrophoresis determination of loratadine in tablets.

  Die Pharmazie 20040401

• Re: Effects of loratadine... by Andersson et al.

  Acta oto-laryngologica 20040401

• Simultaneous determination of itraconazole and hydroxyitraconazole in human plasma by high-performance liquid chromatography.

  Journal of chromatography. A 20040326

• Evaluation of an association between loratadine and hypospadias--United States, 1997-2001.

  MMWR. Morbidity and mortality weekly report 20040319

• High-performance liquid chromatographic method for the bioequivalence evaluation of desloratadine fumarate tablets in dogs.

  Journal of pharmaceutical and biomedical analysis 20040310

• Nociceptive and edematogenic responses elicited by a crude bristle extract of Lonomia obliqua caterpillars.

  Toxicon : official journal of the International Society on Toxinology 20040301

• Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040301

• Comparison of the effects of fluticasone propionate aqueous nasal spray and loratadine on daytime alertness and performance in children with seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040301

• Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.

  Managed care interface 20040201

• Comparative clinical efficacy, onset and duration of action of levocetirizine and desloratadine for symptoms of seasonal allergic rhinitis in subjects evaluated in the Environmental Exposure Unit (EEU).

  International journal of clinical practice 20040201

• Determination of loratadine in human plasma by HPLC with fluorescence detector and study on its bioavailability.

  Yao xue xue bao = Acta pharmaceutica Sinica 20040201

• [Respiratory allergies in the child and the adult].

  La Revue du praticien 20040131

• Determination of loratadine in human plasma by liquid chromatography electrospray ionization ion-trap tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20040127

• Glottis oedema due to loratadine.

  Allergy 20040101

• Human liver aldehyde oxidase: inhibition by 239 drugs.

  Journal of clinical pharmacology 20040101

• Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.

  Current medical research and opinion 20040101

• Therapeutic and economic consequences of OTC loratadine.

  The Annals of pharmacotherapy 20040101

• Inhibition of cold urticaria by desloratadine.

  The Journal of dermatological treatment 20040101

• Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040101

• The risk of esophageal obstruction associated with an anti-allergy medication (Claritin-D 24-Hour--original formulation).

  Pharmacoepidemiology and drug safety 20040101

• Cetirizine: a review of its use in allergic disorders.

  Drugs 20040101

• Evaluation of the utilization patterns of leukotriene modifiers in a large managed care health plan.

  Journal of managed care pharmacy : JMCP 20040101

• Treatment of allergic rhinitis during pregnancy.

  American journal of rhinology 20040101

• Pharmacokinetics and bioequivalence study of a generic desloratadine tablet formulation in healthy male volunteers.

  Arzneimittel-Forschung 20040101

• [Assessment of the clinical efficacy and safety of epinastine plus pseudoephedrine vs loratadine plus pseudoephedrine in perennial allergic rhinitis].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

• A randomized, double-blind, parallel-group study, comparing the efficacy and safety of rupatadine (20 and 10 mg), a new PAF and H1 receptor-specific histamine antagonist, to loratadine 10 mg in the treatment of seasonal allergic rhinitis.

  Journal of investigational allergology & clinical immunology 20040101

• A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of ebastine (20 mg and 10 mg) to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis.

  Journal of investigational allergology & clinical immunology 20040101

• Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines.

  Allergy and asthma proceedings 20040101

• A comparative study on the effects of naltrexone and loratadine on uremic pruritus.

  Dermatology (Basel, Switzerland) 20040101

• Determination of donepezil hydrochloride (E2020) in plasma by liquid chromatography-mass spectrometry and its application to pharmacokinetic studies in healthy, young, Chinese subjects.

  Journal of chromatographic science 20040101

• Identification of allergic disease among users of antihistamines.

  Journal of managed care pharmacy : JMCP 20040101

• Reported case of severe hepatotoxicity likely due to fluconazole and not desloratadine.

  Acta haematologica 20040101

• Safety and tolerability of treatments for allergic rhinitis in children.

  Drug safety 20040101

• The economic impact of payer policies after the Rx-to-OTC switch of second-generation antihistamines.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20040101

• Direct injection of 96-well organic extracts onto a hydrophilic interaction chromatography/tandem mass spectrometry system using a silica stationary phase and an aqueous/organic mobile phase.

  Rapid communications in mass spectrometry : RCM 20040101

• [Autoimmune urticaria. Treatment with methotrexate].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101

• Effect of betamethasone-loratadine combination therapy on severe exacerbations of allergic rhinitis : a randomised, controlled trial.

  Clinical drug investigation 20040101

• Actual therapeutic management of allergic and hyperreactive nasal disorders.

  GMS current topics in otorhinolaryngology, head and neck surgery 20040101

• Montelukast improves symptoms of seasonal allergic rhinitis over a 4-week treatment period.

  Allergy 20031201

• Transitioning the second-generation antihistamines to over-the-counter status: a cost-effectiveness analysis.

  Medical care 20031201

• Effects of loratadine on red wine-induced symptoms and signs of rhinitis.

  Acta oto-laryngologica 20031201

• Simultaneous determination of loratadine and pseudoephedrine sulfate in pharmaceutical formulation by RP-LC and derivative spectrophotometry.

  Journal of pharmaceutical and biomedical analysis 20031124

• Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats.

  Brain research 20031121

• Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.

  British journal of cancer 20031117

• Desloratadine for allergic rhinitis.

  American family physician 20031115

• Patient, medicate thyself.

  Texas medicine 20031101

• [Modern antihistaminics against allergic rhinitis. Better breathing without side effects].

  MMW Fortschritte der Medizin 20031030

• Reliable and specific high-performance liquid chromatographic method for simultaneous determination of loratadine and its metabolite in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031025

• Twenty-four-hour activity and consistency of activity of levocetirizine and desloratadine in the skin.

  British journal of clinical pharmacology 20031001

• Comparison of the effects of desloratadine and levocetirizine on histamine-induced wheal, flare and itch in human skin.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20031001

• Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment.

  The Journal of allergy and clinical immunology 20031001

• Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.

  The Journal of allergy and clinical immunology 20031001

• Prospects for antihistamines in the treatment of asthma.

  The Journal of allergy and clinical immunology 20031001

• A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

• Rush venom immunotherapy in patients experiencing recurrent systemic reactions to conventional venom immunotherapy.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

• Loratadine, desloratadine and pregnancy: don't use, risk of hypospadias.

  Prescrire international 20031001

• The effects of montelukast on intradermal wheal and flare.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20030901

• The role of leukotrienes in nasal allergy.

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20030901

• Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.

  Bioorganic & medicinal chemistry letters 20030818

• Phenytoin toxicity due to fluoropyrimidines (5FU/capecitabine): three case reports.

  British journal of cancer 20030818

• A sensitive LC/MS/MS method using silica column and aqueous-organic mobile phase for the analysis of loratadine and descarboethoxy-loratadine in human plasma.

  Journal of pharmaceutical and biomedical analysis 20030808

• Studies on performance and sleepiness with the H1-antihistamine, desloratadine.

  Aviation, space, and environmental medicine 20030801

• Efficacy of azelastine nasal spray in patients with an unsatisfactory response to loratadine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801

• Coupon programs curb antihistamine utilization.

  Managed care (Langhorne, Pa.) 20030801

• Pharmacokinetic properties of single-dose loratadine and ambroxol alone and combined in tablet formulations in healthy men.

  Clinical therapeutics 20030801

• Validation of a sensitive and automated 96-well solid-phase extraction liquid chromatography-tandem mass spectrometry method for the determination of desloratadine and 3-hydroxydesloratadine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725

• Cc-chemokine eotaxin as a marker of efficacy of specific immunotherapy in patients with intermittent IgE-mediated allergic rhinoconjunctivitis.

  Allergy 20030701

• Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma.

  The Journal of allergy and clinical immunology 20030701

• Efficacy of montelukast, in combination with loratadine, in the treatment of delayed pressure urticaria.

  The Journal of allergy and clinical immunology 20030701

• Pharmacokinetics of loratadine and its active metabolite descarboethoxyloratadine in healthy Chinese subjects.

  Acta pharmacologica Sinica 20030701

• Comparison of ketotifen fumarate ophthalmic solution alone, desloratadine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: a double-masked, placebo- and active-controlled trial.

  Clinical therapeutics 20030701

• Pharmacological characterization of the novel histamine H3-receptor antagonist N-(3,5-dichlorophenyl)-N'-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687).

  The Journal of pharmacology and experimental therapeutics 20030601

• Comparison of the effects of desloratadine 5-mg daily and placebo on nasal airflow and seasonal allergic rhinitis symptoms induced by grass pollen exposure.

  Allergy 20030601

• Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study.

  The Journal of allergy and clinical immunology 20030601

• Effects of mediator antagonism on mannitol and adenosine monophosphate challenges.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030601

• Montelukast as an adjuvant to mainstay therapies in patients with seasonal allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030601

• The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis.

  British journal of clinical pharmacology 20030601

• Management of rhinitis and asthma in pregnancy.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030601

• Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030601

• [Medicinal drugs and automobile driving ability].

  Therapeutische Umschau. Revue therapeutique 20030601

• [Clinical aspects of anti-inflammatory action of antihistamines].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601

• Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: influence of receptor reserve and dissociation kinetics.

  European journal of pharmacology 20030530

• [Antihistaminics. Side effects also after raising dosage at the placebo level].

  MMW Fortschritte der Medizin 20030529

• [In seasonal and perennial rhinitis. Superiority to standard H1 blockers].

  MMW Fortschritte der Medizin 20030529

• [Multicenter study of the effectiveness and tolerability of desloratadine in seasonal allergic rhinitis].

  Orvosi hetilap 20030525

• First do no harm: managing antihistamine impairment in patients with allergic rhinitis.

  The Journal of allergy and clinical immunology 20030501

• Fluticasone nasal spray and the combination of loratadine and montelukast in seasonal allergic rhinitis.

  Archives of otolaryngology--head & neck surgery 20030501

• High dose cetirizine: a case report.

  Cutis 20030501

• Test your knowledge. Patient with a skin rash.

  Australian family physician 20030501

• Do leukotriene receptor antagonists have a place in pharmacotherapy of allergic rhinitis?

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501

• Fluticasone propionate aqueous nasal spray provided significantly greater improvement in daytime and nighttime nasal symptoms of seasonal allergic rhinitis compared with montelukast.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501

• Impurity profile study of loratadine.

  Journal of pharmaceutical and biomedical analysis 20030424

• Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled trial.

  Journal of the American Academy of Dermatology 20030401

• Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis.

  The Journal of allergy and clinical immunology 20030401

• Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma.

  International archives of allergy and immunology 20030401

• Effects of thyroid hormones on basal and stimulated gastric acid secretion due to histamine, carbachol and pentagastrin in rats.

  Saudi medical journal 20030401

• [Older antihistaminics often act as sedatives. Hay fever gone -- reaction capacity, too].

  MMW Fortschritte der Medizin 20030327

• Spectrophotometric determination of binary mixtures of pseudoephedrine with some histamine H1-receptor antagonists using derivative ratio spectrum method.

  Journal of pharmaceutical and biomedical analysis 20030326

• Capillary electrophoresis determination of loratadine and related impurities.

  Journal of pharmaceutical and biomedical analysis 20030310

• Ventricular tachycardia following ingestion of a commonly used antihistamine.

  The Medical journal of Australia 20030303

• P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists.

  Drug metabolism and disposition: the biological fate of chemicals 20030301

• Blood basophil numbers in chronic ordinary urticaria and healthy controls: diurnal variation, influence of loratadine and prednisolone and relationship to disease activity.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030301

• Fetal safety of loratadine use in the first trimester of pregnancy: a multicenter study.

  The Journal of allergy and clinical immunology 20030301

• Efficacy and safety of desloratadine in the treatment of perennial allergic rhinitis.

  The Journal of allergy and clinical immunology 20030301

• Decongestant effects of antihistamines: a class effect?

  The Journal of allergy and clinical immunology 20030301

• Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone.

  Pacing and clinical electrophysiology : PACE 20030301

• Fox-Fordyce disease.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20030301

• Efficacy of ebastine in the control of nasal congestion associated with allergic rhinitis.

  Methods and findings in experimental and clinical pharmacology 20030301

• [Effects of H1 blocker and inhaled corticosteroids on asthmatic patients with allergic rhinitis].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20030301

• [Determination of donepezil in human plasma by HPLC-MS].

  Yao xue xue bao = Acta pharmaceutica Sinica 20030301

• Pre and post treatment mucociliary function in allergic rhinitis in three different treatment modalities.

  The Medical journal of Malaysia 20030301

• Simultaneous determination of montelukast and loratadine by HPLC and derivative spectrophotometric methods.

  Journal of pharmaceutical and biomedical analysis 20030226

• Desloratadine: a nonsedating antihistamine.

  The Annals of pharmacotherapy 20030201

• Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.

  The Journal of allergy and clinical immunology 20030201

• Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030201

• Loratadine: hydroxymethylation in syrup.

  Die Pharmazie 20030201

• OTC loratadine.

  The Medical letter on drugs and therapeutics 20030106

• The effect of ketotifen on inflammatory markers in allergic conjunctivitis: an open, uncontrolled study.

  BMC ophthalmology 20030101

• Effects of second-generation histamine H1 receptor antagonists on the active avoidance response in rats.

  Clinical and experimental pharmacology & physiology 20030101

• FDA approves OTC Claritin.

  FDA consumer 20030101

• Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.

  Arzneimittel-Forschung 20030101

• Chronic urticaria: a role for newer immunomodulatory drugs?

  American journal of clinical dermatology 20030101

• [Tongue angioedema associated with angiotensin-converting enzyme inhibitor (diagnosis, differential diagnosis, treatment)].

  Medicina (Kaunas, Lithuania) 20030101

• Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.

  BMC family practice 20030101

• Desloratadine: an update of its efficacy in the management of allergic disorders.

  Drugs 20030101

• Severe hepatotoxicity after application of desloratadine and fluconazole.

  Acta haematologica 20030101

• [Acute interstitial nephritis induced by loratadine].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20030101

• Fixed drug eruption due to loratadine.

  Allergologia et immunopathologia 20030101

• Effects of perinatal loratadine exposure on male rat reproductive organ development.

  Reproductive toxicology (Elmsford, N.Y.) 20030101

• The bronchodilatory effects of loratadine, terbutaline, and both together versus placebo in childhood asthma.

  Journal of investigational allergology & clinical immunology 20030101

• Therapy in the management of the rhinitis/asthma complex.

  Allergy and asthma proceedings 20030101

• Antihistamines in the treatment of dermatitis.

  Journal of cutaneous medicine and surgery 20030101

• Comparative pharmacology of H1 antihistamines: clinical relevance.

  The American journal of medicine 20021216

• Allergy warning.

  Newsweek 20021209

• Loratadine is viable in patients with geriatric rhinitis.

  Geriatrics 20021201

• [The place of new antihistamines in allergy management. Apropos of desloratadine].

  Allergie et immunologie 20021201

• The new antihistamines--desloratadine and levocetirizine: a review.

  Journal of drugs in dermatology : JDD 20021201

• Clinical pharmacology of H1-antihistamines in the skin.

  The Journal of allergy and clinical immunology 20021101

• Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021101

• Severe human urticaria produced by ant (Odontomachus bauri, Emery 1892) (Hymenoptera: Formicidae) venom.

  International journal of dermatology 20021101

• Rapid effects of olopatadine hydrochloride on the histamine-induced skin responses.

  The Journal of dermatology 20021101

• Determination of some histamine H1-receptor antagonists in dosage forms.

  Journal of pharmaceutical and biomedical analysis 20021015

• Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021001

• Desloratadine reduces allergen challenge-induced mucinous secretion and plasma exudation in allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021001

• Desloratidine for the treatment of chronic urticaria.

  Skin therapy letter 20021001

• Single-patient drug trial methodology for allergic rhinitis.

  The Annals of pharmacotherapy 20020901

• Of injuries and antihistamines and dosing.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020901

• Increased risk of serious injury following an initial prescription for diphenhydramine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020901

• Efficacy of ebastine, cetirizine, and loratadine in histamine cutaneous challenges.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020901

• Mizolastine provides effective symptom relief in patients suffering from perennial allergic rhinitis: a double-blind, placebo-controlled study versus loratadine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020901

• Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor.

  European journal of pharmacology 20020809

• [The result of neglected or erroneous treatment. Mentally handicapped by hay fever].

  MMW Fortschritte der Medizin 20020711

• Topical olopatadine and loratadine compared with loratadine alone.

  Current allergy and asthma reports 20020701

• Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020701

• The combination of single-dose montelukast and loratadine on exercise-induced bronchospasm in children.

  The European respiratory journal 20020701

• LC determination of loratadine and related impurities.

  Journal of pharmaceutical and biomedical analysis 20020620

• Stability indicating methods for the determination of loratadine in the presence of its degradation product.

  Journal of pharmaceutical and biomedical analysis 20020615

• Simultaneous development of six LC-MS-MS methods for the determination of multiple analytes in human plasma.

  Journal of pharmaceutical and biomedical analysis 20020615

• Comparison of cetirizine, ebastine and loratadine in the treatment of immediate mosquito-bite allergy.

  Allergy 20020601

• Comparison of a nasal glucocorticoid, antileukotriene, and a combination of antileukotriene and antihistamine in the treatment of seasonal allergic rhinitis.

  The Journal of allergy and clinical immunology 20020601

• Effect of desloratadine versus placebo on nasal airflow and subjective measures of nasal obstruction in subjects with grass pollen-induced allergic rhinitis in an allergen-exposure unit.

  The Journal of allergy and clinical immunology 20020601

• Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial performed in the fall.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020601

• Managed care implications of the approval of generic or over-the-counter nonsedating antihistamines.

  Managed care interface 20020601

• Fluoxetine-induced sexual dysfunction reversed by loratadine.

  The Journal of clinical psychiatry 20020601

• Gateways to Clinical Trials. June 2002.

  Methods and findings in experimental and clinical pharmacology 20020601

• The Rx-to-OTC switch of Claritin, Allegra, and Zyrtec: an unprecedented FDA response to petitioners and the protection of public health.

  The American University law review 20020601

• A comparative study of the side effects between pseudoephedrine in Loratadine plus Pseudoephedrine Sulfate Repetabs Tables and loratadine + pseudoephedrine tablet in treatment of allergic rhinitis in Thai patients.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020601

• Ventricular tachycardia following ingestion of a commonly used antihistamine.

  The Medical journal of Australia 20020506

• The cost of treating allergic rhinitis.

  Current allergy and asthma reports 20020501

• Exercise-induced asthma: is there still a case for histamine?

  The Journal of allergy and clinical immunology 20020501

• Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction.

  The Journal of allergy and clinical immunology 20020501

• Loratadine/nefazodone interaction.

  Clinical pharmacology and therapeutics 20020501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20020501

• Can fall in anti-H. pylori IgG titres indicate eradication?

  The Journal of the Association of Physicians of India 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Comparison of five new antihistamines (H1-receptor antagonists) in patients with allergic rhinitis using nasal provocation studies and skin tests.

  Allergy 20020401

• Clinical evidence for antileukotriene therapy in the management of allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020401

• Therapeutic efficacy and safety of loratadine syrup in childhood atopic dermatitis treated with mometasone furoate 0.1 per cent cream.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020401

• Desloratadine (Clarinex).

  The Medical letter on drugs and therapeutics 20020318

• Complete remission of a primary cutaneous B-cell lymphoma of the lower leg by first-line monotherapy with the CD20-antibody rituximab.

  Journal of cancer research and clinical oncology 20020301

• A randomized, double-blind, placebo-controlled comparison of emedastine 0.05% ophthalmic solution with loratadine 10 mg and their combination in the human conjunctival allergen challenge model.

  Clinical therapeutics 20020301

• Fixed drug eruption due to loratadine.

  The British journal of dermatology 20020301

• Which is more effective for as-needed treatment of seasonal allergy symptoms: intranasal corticosteroids or oral antihistamines?

  The Journal of family practice 20020301

• Cardiotoxicity of new antihistamines and cisapride.

  Toxicology letters 20020227

• [The third-generation antihistaminics. Can they prevent the tier change?].

  MMW Fortschritte der Medizin 20020214

• Effects of the selective H1 and H2 histamine receptor antagonists loratadine and ranitidine on autonomic control of the heart.

  Anesthesiology 20020201

• Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-study).

  The Journal of allergy and clinical immunology 20020201

• Medical management of Cronkhite-Canada syndrome.

  Southern medical journal 20020201

• A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020201

• [Clinical evaluation of the ocular safety of Amukine 0.06% solution for local application versus povidone iodine (Bétadine) 5% solution for ocular irrigation) in preoperative antisepsis].

  Journal francais d'ophtalmologie 20020201

• Are antihistamines useful in managing asthma?

  Current opinion in allergy and clinical immunology 20020201

• The effect of loratadine in exercise-induced asthma.

  Archives of disease in childhood 20020101

• Relationship between direct-to-consumer advertising and physician diagnosing and prescribing.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020101

• Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.

  Clinical pharmacokinetics 20020101

• [Comparative antihistamine and anti-allergic effects of various antihistamine preparations].

  Terapevticheskii arkhiv 20020101

• Med-psych drug-drug interactions update.

  Psychosomatics 20020101

• A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101

• Potential cardiac toxicity of H1-antihistamines.

  Clinical allergy and immunology 20020101

• H1-antihistamines in children.

  Clinical allergy and immunology 20020101

• 24-hour efficacy of once-daily desloratadine therapy in patients with seasonal allergic rhinitis [ISRCTN32042139].

  BMC family practice 20020101

• Desloratadine demonstrates dose proportionality in healthy adults after single doses.

  Clinical pharmacokinetics 20020101

• Oral bioavailability of desloratadine is unaffected by food.

  Clinical pharmacokinetics 20020101

• A pharmacokinetic profile of desloratadine in healthy adults, including elderly.

  Clinical pharmacokinetics 20020101

• Effect of race and sex on single and multiple dose pharmacokinetics of desloratadine.

  Clinical pharmacokinetics 20020101

• Lack of clinically relevant interaction between desloratadine and erythromycin.

  Clinical pharmacokinetics 20020101

• Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole.

  Clinical pharmacokinetics 20020101

• Erythrodermia to pseudoephedrine in a patient with contact allergy to phenylephrine.

  Allergologia et immunopathologia 20020101

• Urticaria to cetirizine.

  Journal of investigational allergology & clinical immunology 20020101

• Investigation of an enhanced resolution triple quadrupole mass spectrometer for high-throughput liquid chromatography/tandem mass spectrometry assays.

  Rapid communications in mass spectrometry : RCM 20020101

• Efficacy of once-daily desloratadine/pseudoephedrine for relief of nasal congestion.

  Allergy and asthma proceedings 20020101

• Therapeutic points of intervention and clinical implications: role of desloratadine.

  Allergy 20020101

• Impact and modulation of nasal obstruction.

  Allergy 20020101

• Advances in allergy management.

  Allergy 20020101

• Ocular drying associated with oral antihistamines (loratadine) in the normal population-an evaluation of exaggerated dose effect.

  Advances in experimental medicine and biology 20020101

• Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.

  Drugs under experimental and clinical research 20020101

• QTc prolongation and drugs.

  Clinical pharmacology and therapeutics 20011201

• Comparative onset of action and symptom relief with cetirizine, loratadine, or placebo in an environmental exposure unit in subjects with seasonal allergic rhinitis: confirmation of a test system.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011201

• Superiority of an intranasal corticosteroid compared with an oral antihistamine in the as-needed treatment of seasonal allergic rhinitis.

  Archives of internal medicine 20011126

• Variant effect of first- and second-generation antihistamines as clues to their mechanism of action on the sneeze reflex in the common cold.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011101

• Desloratadine reduces nasal congestion in patients with intermittent allergic rhinitis.

  Allergy 20011101

• Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs).

  Biochemical pharmacology 20011101

• Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal, flare, and itch in human skin.

  Allergy 20011001

• The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.

  The American journal of managed care 20011001

• Effect of specific immunotherapy versus loratadine on serum adhesion molecules.

  Allergie et immunologie 20011001

• In vitro characterization of the inhibition profile of loratadine, desloratadine, and 3-OH-desloratadine for five human cytochrome P-450 enzymes.

  Drug metabolism and disposition: the biological fate of chemicals 20010901

• Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010901

• Do antihistamines impair school performance in children?

  The Journal of family practice 20010901

• Controlled clinical study of the efficacy of loratadine in Nigerian patients with allergic rhinitis.

  The Nigerian postgraduate medical journal 20010901

• A double-blind, placebo-controlled, and randomized study of loratadine (Clarityne) syrup for the treatment of allergic rhinitis in children aged 3 to 12 years.

  Asian Pacific journal of allergy and immunology 20010901

• [Effect of loratadine in children with allergic rhinitis].

  Orvosi hetilap 20010826

• Applications of new liquid chromatography-tandem mass spectrometry technologies for drug development support.

  Journal of chromatography. A 20010810

• Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.

  Modern healthcare 20010806

• Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein.

  Drug metabolism and disposition: the biological fate of chemicals 20010801

• Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells.

  The Journal of allergy and clinical immunology 20010801

• [Urticaria. Finally undisturbed sleep].

  MMW Fortschritte der Medizin 20010726

• ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.

  Journal of medicinal chemistry 20010719

• Polarographic behaviour of loratadine and its direct determination in pharmaceutical formulation and human plasma by cathodic adsorptive stripping voltammetry.

  Journal of pharmaceutical and biomedical analysis 20010701

• FDA panel recommends OTC status for second-generation antihistamines.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010701

• Triamcinolone: new and old indications.

  Expert opinion on pharmacotherapy 20010701

• High-dose loratadine exposure in a six-year-old child.

  Veterinary and human toxicology 20010601

• Olopatadine ophthalmic solution adjunctive to loratadine compared with loratadine alone in patients with active seasonal allergic conjunctivitis symptoms.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010601

• Antihistamines and serum adhesion molecule levels.

  Allergie et immunologie 20010601

• Synergistic antiallergic activity of combined histamine H1- and cysteinyl leukotriene1-receptor blockade in human bronchus.

  Life sciences 20010511

• Determination of loratadine in human plasma by high-performance liquid chromatographic method with ultraviolet detection.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• [Seasonal allergic rhinitis. Nasal obstruction can also beh improved].

  MMW Fortschritte der Medizin 20010503

• Children's school performance is not impaired by short-term administration of diphenhydramine or loratadine.

  The Journal of pediatrics 20010501

• A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.

  The American journal of managed care 20010501

• Newer antihistamines.

  The Medical letter on drugs and therapeutics 20010430

• Sensitive liquid chromatography-tandem mass spectrometry method for the determination of loratadine and its major active metabolite descarboethoxyloratadine in human plasma.

  Journal of chromatography. A 20010420

• Evaluation of a four-channel multiplexed electrospray triple quadrupole mass spectrometer for the simultaneous validation of LC/MS/MS methods in four different preclinical matrixes.

  Analytical chemistry 20010415

• [A new antihistamine. Inhibiting inflammation in rhinorrhea and nasal congestion].

  MMW Fortschritte der Medizin 20010405

• Desloratadine: A new, nonsedating, oral antihistamine.

  The Journal of allergy and clinical immunology 20010401

• Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.

  Molecular pharmacology 20010301

• Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation.

  Clinical pharmacology and therapeutics 20010301

• An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers.

  European journal of clinical pharmacology 20010301

• Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.

  Clinical therapeutics 20010301

• Pharmacology and clinical efficacy of desloratadine as an anti-allergic and anti-inflammatory drug.

  Expert opinion on investigational drugs 20010301

• Safety of antihistamines in children.

  Drug safety 20010101

• Decongestant efficacy of desloratadine in patients with seasonal allergic rhinitis.

  Allergy 20010101

• Desloratadine activity in concurrent seasonal allergic rhinitis and asthma.

  Allergy 20010101

• Desloratadine in the treatment of chronic idiopathic urticaria.

  Allergy 20010101

• Desloratadine: a new approach in the treatment of allergy as a systematic disease--pharmacology and clinical overview. Introduction.

  Allergy 20010101

• The pharmacologic profile of desloratadine: a review.

  Allergy 20010101

• Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study.

  International journal of dermatology 20010101

• Desloratadine.

  Drugs 20010101

• [Childhood asthma and viral infection: interactions and therapeutic possibilities].

  Allergologia et immunopathologia 20010101

• Clinical prescribing of allergic rhinitis medication in the preschool and young school-age child: what are the options?

  BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20010101

• [Co-administration of histamine H1 antagonist and oral anticoagulants].

  Acta otorrinolaringologica espanola 20010101

• [Azelastine in the treatment of allergic conjunctivitis].

  Vestnik oftalmologii 20010101

• [The effect of second generation histamine antagonists on the heart].

  Pneumonologia i alergologia polska 20010101

• Evaluation of quality of life in children and teenagers with allergic rhinitis: adaptation and validation of the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ).

  Allergologia et immunopathologia 20010101

• Treatment of urticaria. An evidence-based evaluation of antihistamines.

  American journal of clinical dermatology 20010101

• [Approaches to prevention and treatment of latex allergy].

  Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20010101

• The acute and sub-chronic effects of levocetirizine, cetirizine, loratadine, promethazine and placebo on cognitive function, psychomotor performance, and weal and flare.

  Current medical research and opinion 20010101

• Mechanism responsible for epileptogenic activity by first-generation H1-antagonists in rats.

  Brain research 20001222

• Loratadine versus cetirizine: assessment of somnolence and motivation during the workday.

  Clinical therapeutics 20000501

• Sedation with 'non-sedating' antihistamines: four prescription-event monitoring studies in general practice.

  BMJ (Clinical research ed.) 20000429

• Loratadine blockade of K(+) channels in human heart: comparison with terfenadine under physiological conditions.

  The Journal of pharmacology and experimental therapeutics 20000101

• Antiallergic effects of H1-receptor antagonists.

  Allergy 20000101

• Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine.

  Bioorganic & medicinal chemistry 19990701

• Double-blind trials of azelastine nasal spray monotherapy versus combination therapy with loratadine tablets and beclomethasone nasal spray in patients with seasonal allergic rhinitis. Rhinitis Study Groups.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19990601

• Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs.

  British journal of clinical pharmacology 19990301

• Central nervous system effects of H1-receptor antagonists in the elderly.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19990201

• Efficacy and safety of mizolastine 10 mg in a placebo-controlled comparison with loratadine in chronic idiopathic urticaria: results of the MILOR Study.

  Journal of the European Academy of Dermatology and Venereology : JEADV 19990101

• Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines.

  Molecular pharmacology 19980701

• Loratadine-pseudoephedrine in children with allergic rhinitis, a controlled double-blind trial.

  British journal of clinical pharmacology 19980201

• Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics.

  American journal of respiratory and critical care medicine 19970601

• A review of loratadine in the treatment of patients with allergic bronchial asthma.

  Clinical therapeutics 19970101

• The effect of cetirizine and loratadine on codeine-induced histamine release in human skin in vivo assessed by cutaneous microdialysis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 19960901

• Intranasal fluticasone propionate versus loratadine in the treatment of adolescent patients with seasonal allergic rhinitis.

  The Journal of allergy and clinical immunology 19960201

• Astemizole-D causes less sleep impairment than loratadine-D.

  The Journal of international medical research 19950101

• Loratadine and ventricular tachycardia.

  The American journal of cardiology 19940715

• Effect of loratadine on human eosinophil function in vitro.

  Annals of allergy 19931001

• Comparative effects of loratadine and azatadine in the treatment of seasonal allergic rhinitis.

  Asian Pacific journal of allergy and immunology 19901201

• Histamine and asthma: an appraisal based on specific H1-receptor antagonism.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19900801

• [Therapy of acute and chronic urticaria and of Quincke's edema].

  Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 19890516