808118-40-3 | Fg-4592

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$42.00	$29.00
10mg	95%	in stock	$67.00	$47.00
25mg	95%	in stock	$74.00	$52.00
50mg	95%	in stock	$118.00	$83.00
100mg	95%	in stock	$216.00	$151.00
250mg	95%	in stock	$249.00	$174.00
500mg	95%	in stock	$377.00	$264.00
1g	95%	in stock	$455.00	$318.00
5g	95%	in stock	$1,169.00	$818.00

Description

• Catalog Number: AB48138
• Chemical Name: Fg-4592
• CAS Number: 808118-40-3
• Molecular Formula: C19H16N2O5
• Molecular Weight: 352.3407
• MDL Number: MFCD20040519
• SMILES: OC(=O)CNC(=O)c1nc(C)c2c(c1O)ccc(c2)Oc1ccccc1

Computed Properties

• Complexity: 508
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: 3.4

Upstream Synthesis Route

N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, commonly referred to as $name$, is a versatile compound that finds extensive utility in the realm of chemical synthesis. With its unique molecular structure, $name$ serves as a crucial building block in the creation of various pharmaceuticals, agrochemicals, and specialty chemicals.In chemical synthesis, $name$ acts as a key intermediate in the production of complex organic molecules. Its presence enables the formation of intricate chemical structures through controlled reactions and strategic functional group manipulations. By incorporating $name$ into synthetic pathways, chemists can streamline processes, enhance efficiency, and access novel compounds that have practical applications in diverse industries.Moreover, the distinctive properties of $name$, including its reactive functional groups and stereochemical features, contribute significantly to the success of multi-step synthesis. Chemists leverage these attributes to introduce specific functionalities, modify molecular architectures, and generate compounds with tailored properties for targeted applications. As a result, $name$ plays a critical role in advancing the frontier of synthetic chemistry and enabling the development of innovative molecules with valuable properties.Overall, the application of N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine in chemical synthesis exemplifies its indispensable role as a versatile and indispensable tool for creating intricate molecular structures with diverse functionalities.

Literature

• Cadmium Exposure Inhibits Branching Morphogenesis and Causes Alterations Consistent With HIF-1α Inhibition in Human Primary Breast Organoids.

  Toxicological sciences : an official journal of the Society of Toxicology 20180801

• Prolyl-4-Hydroxylases Inhibitor Stabilizes HIF-1α and Increases Mitophagy to Reduce Cell Death After Experimental Retinal Detachment.

  Investigative ophthalmology & visual science 20160401

• Targeting the hypoxia-sensing pathway in clinical hematology.

  Stem cells translational medicine 20140201

• First-in-class anemia drug takes aim at Amgen's dominion.

  Nature biotechnology 20131101