82854-37-3 | Echinacoside

Packsize	Purity	Availability	Price	Discounted Price
5mg	≥95%	in stock	$80.00	$56.00
10mg	≥95%	in stock	$141.00	$99.00
100mg	98+%	in stock	$218.00	$153.00

Description

• Catalog Number: AH49954
• Chemical Name: Echinacoside
• CAS Number: 82854-37-3
• Molecular Formula: C35H46O20
• Molecular Weight: 786.7277
• MDL Number: MFCD00075695
• SMILES: OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](OCCc3ccc(c(c3)O)O)[C@@H]([C@H]([C@@H]2OC(=O)/C=C/c2ccc(c(c2)O)O)O[C@@H]2O[C@@H](C)[C@@H]([C@H]([C@H]2O)O)O)O)[C@@H]([C@H]([C@@H]1O)O)O

Computed Properties

• Complexity: 1230
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 15
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 55
• Hydrogen Bond Acceptor Count: 20
• Hydrogen Bond Donor Count: 12
• Rotatable Bond Count: 14
• XLogP3: -2.1

Literature

• Echinacoside Protects Against MPP(+)-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation.

  Neuroscience bulletin 20160801

• Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone.

  Journal of neurochemistry 20130201

• Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors.

  Chemico-biological interactions 20120830

• Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone.

  Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120701

• Echinacoside stimulates cell proliferation and prevents cell apoptosis in intestinal epithelial MODE-K cells by up-regulation of transforming growth factor-β1 expression.

  Journal of pharmacological sciences 20120101

• HPLC determination of antilipoxygenase activity of a water infusion of Ligustrum vulgare L. leaves and some of its constituents.

  Molecules (Basel, Switzerland) 20110928

• Effects of 2-aminoindan-2-phosphonic acid treatment on the accumulation of salidroside and four phenylethanoid glycosides in suspension cell culture of Cistanche deserticola.

  Plant cell reports 20110401

• Production of acteoside from Cistanche tubulosa by β-glucosidase.

  Pakistan journal of pharmaceutical sciences 20110401

• Phytochemical and immunomodulatory properties of an Echinacea laevigata (Asteraceae) tincture.

  Journal of alternative and complementary medicine (New York, N.Y.) 20110401

• Separation and purification of echinacoside from Penstemon barbatus (Can.) Roth by recycling high-speed counter-current chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

• Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells.

  Planta medica 20101001

• Neurotrophic and neurorescue effects of Echinacoside in the subacute MPTP mouse model of Parkinson's disease.

  Brain research 20100730

• Suppression of nitric oxide implicated in the protective effect of echinacoside on H2O2-induced PC12 cell injury.

  Natural product communications 20100401

• An approach to identifying sequential metabolites of a typical phenylethanoid glycoside, echinacoside, based on liquid chromatography-ion trap-time of flight mass spectrometry analysis.

  Talanta 20091215

• Protective effects of echinacoside, one of the phenylethanoid glycosides, on H(2)O(2)-induced cytotoxicity in PC12 cells.

  Planta medica 20091101

• Echinacoside retards cellular senescence of human fibroblastic cells MRC-5.

  Die Pharmazie 20091101

• Echinacoside elicits endothelium-dependent relaxation in rat aortic rings via an NO-cGMP pathway.

  Planta medica 20091001

• Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance.

  Annals of botany 20091001

• A sensitive and specific liquid chromatography/tandem mass spectrometry method for determination of echinacoside and its pharmacokinetic application in rats.

  Biomedical chromatography : BMC 20090601

• Metabolism of echinacoside, a good antioxidant, in rats: isolation and identification of its biliary metabolites.

  Drug metabolism and disposition: the biological fate of chemicals 20090201

• [Research progress on pharmacological activities of echinacoside].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090201

• [Effects of precursor feeding and fungal elicitors on secondary metabolits in cell suspension culture of Cistanche deserticola].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090201

• [Preliminary study on variation pattern of Cistanche deserticola].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

• Echinacoside prevents the striatal extracellular levels of monoamine neurotransmitters from diminution in 6-hydroxydopamine lesion rats.

  Journal of ethnopharmacology 20071203

• [Study on secondary metabolic organ of echinacoside in herbs of Cistanche tubulosa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

• [Inoculation experiments of Cistanche tubulosa on 8 introduced Tamarix species].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001

• [Study on reproduction biology of Cistanche deserticola--seedling emergence and flowering].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

• Protection of echinacoside against acute lung injury caused by oleic acid in rats.

  Free radical research 20070701

• [Study on processing method of Cistanche tubulosa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701

• Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease.

  European journal of pharmacology 20070614

• Protective effects of echinacoside on carbon tetrachloride-induced hepatotoxicity in rats.

  Toxicology 20070322

• Determination of echinacoside in rat serum by reversed-phase high-performance liquid chromatography with ultraviolet detection and its application to pharmacokinetics and bioavailability.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061205

• Investigation of anti-hyaluronidase treatment on vocal fold wound healing.

  Journal of voice : official journal of the Voice Foundation 20060901

• [Studied of dry matter accumulation and echinacoside content of Cistanche tubulosa in Huabei plain].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801

• Synergistic antioxidative effects of alkamides, caffeic acid derivatives, and polysaccharide fractions from Echinacea purpurea on in vitro oxidation of human low-density lipoproteins.

  Journal of agricultural and food chemistry 20051130

• [The determination of echinacoside and acteoside in herbs of Cistanche tubulosa].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601

• Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis.

  European journal of pharmacology 20041128

• [Determination of phenylethanoid glycosides from Cistanche deserticola in spring and autumn with LC-MS].

  Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040301

• Improvement of phenylethanoid glycosides production by a fungal elicitor in cell suspension culture of Cistanche deserticola.

  Biotechnology letters 20030901

• Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method.

  Journal of agricultural and food chemistry 20021218

• [Determination of echinacoside in congrong spirit by reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20021101

• Rapid and non-destructive determination of the echinacoside content in Echinacea roots by ATR-IR and NIR spectroscopy.

  Planta medica 20021001

• Simultaneous analysis of alkamides and caffeic acid derivatives for the identification of Echinacea purpurea, Echinacea angustifolia, Echinacea pallida and Parthenium integrifolium roots.

  Planta medica 20020601

• [Metabolic regulation of phenylethanoid glycosides from Herba cistanches in dogs' gastrointestine].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010601

• [Separation of echinacoside by reversed-phase preparative high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20010501