83799-24-0 | 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$30.00	$21.00
1g	95%	in stock	$90.00	$63.00
5g	95%	in stock	$243.00	$170.00
10g	95%	in stock	$403.00	$282.00
25g	95%	in stock	$768.00	$537.00

Description

• Catalog Number: AI56882
• Chemical Name: 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
• CAS Number: 83799-24-0
• Molecular Formula: C32H39NO4
• Molecular Weight: 501.6564
• MDL Number: MFCD00871892
• SMILES: OC(=O)C(c1ccc(cc1)C(CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O)O)(C)C

Computed Properties

• Complexity: 678
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 37
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 10
• Undefined Atom Stereocenter Count: 1
• XLogP3: 3

Literature

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  Human brain mapping 20100901

• Rewarding feedback after correct visual discriminations has both general and specific influences on visual cortex.

  Journal of neurophysiology 20100901

• Efficacy of leukotriene antagonists as concomitant therapy in allergic rhinitis.

  The Laryngoscope 20100901

• A quantitative structure-activity relationship for the modulation effects of flavonoids on p-glycoprotein-mediated transport.

  Chemical & pharmaceutical bulletin 20100901

• Preparation and evaluation of fexofenadine microemulsions for intranasal delivery.

  International journal of pharmaceutics 20100816

• Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

  The Journal of clinical investigation 20100802

• Synchronization in G0/G1 enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin.

  Cell biology and toxicology 20100801

• Echinacea purpurea significantly induces cytochrome P450 3A activity but does not alter lopinavir-ritonavir exposure in healthy subjects.

  Pharmacotherapy 20100801

• Immaturities in reward processing and its influence on inhibitory control in adolescence.

  Cerebral cortex (New York, N.Y. : 1991) 20100701

• Effect of metronidazole on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy male volunteers.

  European journal of clinical pharmacology 20100701

• Effects of category-specific costs on neural systems for perceptual decision-making.

  Journal of neurophysiology 20100601

• Melt-in-mouth pellets of fexofenadine hydrochloride using crospovidone as an extrusion-spheronisation aid.

  AAPS PharmSciTech 20100601

• Determination of the antiulcer properties of sodium cromoglycate in pylorus-ligated albino rats.

  Indian journal of pharmacology 20100601

• Overcoming multidrug resistance in human cancer cells by natural compounds.

  Toxins 20100601

• Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100512

• The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100501

• Applications of cold temperature stress to age fractionate Caenorhabditis elegans: a simple inexpensive technique.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20100501

• Second-generation antihistamines for the treatment of chronic idiopathic urticaria.

  Journal of drugs in dermatology : JDD 20100501

• Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100416

• Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation.

  Clinical pharmacokinetics 20100401

• Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.

  Journal of clinical pharmacy and therapeutics 20100401

• Effect of piperine, a major component of black pepper, on the intestinal absorption of fexofenadine and its implication on food-drug interaction.

  Journal of food science 20100401

• Measurement of fexofenadine concentration in micro-sample human plasma by a rapid and sensitive LC-MS/MS employing protein precipitation: application to a clinical pharmacokinetic study.

  Biomedical chromatography : BMC 20100301

• Development and validation of a rapid method for the detection of latrunculol A in plasma.

  Analytical and bioanalytical chemistry 20100301

• Human v6: the medial motion area.

  Cerebral cortex (New York, N.Y. : 1991) 20100201

• In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2.

  Applied microbiology and biotechnology 20100201

• Development of a novel system for estimating human intestinal absorption using Caco-2 cells in the absence of esterase activity.

  Drug metabolism and disposition: the biological fate of chemicals 20100201

• Intellectual enrichment is linked to cerebral efficiency in multiple sclerosis: functional magnetic resonance imaging evidence for cognitive reserve.

  Brain : a journal of neurology 20100201

• Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201

• Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance.

  Combinatorial chemistry & high throughput screening 20100201

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  Indian journal of pharmacology 20100201

• Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.

  International archives of allergy and immunology 20100101

• Use of mannitol inhalation challenge in assessment of cough.

  Lung 20100101

• Clinical pharmacokinetics of fexofenadine enantiomers.

  Expert opinion on drug metabolism & toxicology 20100101

• Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.

  Bioorganic & medicinal chemistry letters 20100101

• Evaluation of treatment satisfaction in children with allergic disease treated with an antihistamine: an international, non-interventional, retrospective study.

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  Naunyn-Schmiedeberg's archives of pharmacology 20100101

• Safety and efficacy of desloratadine in subjects with seasonal allergic rhinitis or chronic urticaria: results of four postmarketing surveillance studies.

  Clinical drug investigation 20100101

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  Current chemical genomics 20100101

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  Frontiers in human neuroscience 20100101

• Rhinorrhea, cough and fatigue in patients taking sitagliptin.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101

• Treatment of congestion in upper respiratory diseases.

  International journal of general medicine 20100101

• Investigation of interactions between poly-L-lysine-coated boron nitride nanotubes and C2C12 cells: up-take, cytocompatibility, and differentiation.

  International journal of nanomedicine 20100101

• Interaction between thymidylate synthase and its cognate mRNA in zebrafish embryos.

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  Journal of chromatographic science 20100101

• Location, Location, Location: Alterations in the Functional Topography of Face- but not Object- or Place-Related Cortex in Adolescents with Autism.

  Frontiers in human neuroscience 20100101

• Gray matter correlates of cognitive ability tests used for vocational guidance.

  BMC research notes 20100101

• Decoding developmental differences and individual variability in response inhibition through predictive analyses across individuals.

  Frontiers in human neuroscience 20100101

• Interaction of silver nanoparticles with Tacaribe virus.

  Journal of nanobiotechnology 20100101

• Listening for recollection: a multi-voxel pattern analysis of recognition memory retrieval strategies.

  Frontiers in human neuroscience 20100101

• Your resting brain CAREs about your risky behavior.

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  Dermatology research and practice 20100101

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  Mediators of inflammation 20100101

• The neural correlates of problem states: testing FMRI predictions of a computational model of multitasking.

  PloS one 20100101

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  Frontiers in aging neuroscience 20100101

• Echoic memory of a single pure tone indexed by change-related brain activity.

  BMC neuroscience 20100101

• Knowing with which eye we see: utrocular discrimination and eye-specific signals in human visual cortex.

  PloS one 20100101

• Imaging the functional connectivity of the Periaqueductal Gray during genuine and sham electroacupuncture treatment.

  Molecular pain 20100101

• A Hybrid Machine Learning Method for Fusing fMRI and Genetic Data: Combining both Improves Classification of Schizophrenia.

  Frontiers in human neuroscience 20100101

• New advances in the treatment of gout: review of pegloticase.

  Therapeutics and clinical risk management 20100101

• Effect of itraconazole on the pharmacokinetics of diclofenac in beagle dogs.

  Scientia pharmaceutica 20100101

• Study of the Complexation Behaviour of Fexofenadine with β-Cyclodextrin.

  Indian journal of pharmaceutical sciences 20100101

• Clinical utility and patient adherence with ebastine for allergic rhinitis.

  Patient preference and adherence 20100101

• Economic value biases uncertain perceptual choices in the parietal and prefrontal cortices.

  Frontiers in human neuroscience 20100101

• Holistic face categorization in higher order visual areas of the normal and prosopagnosic brain: toward a non-hierarchical view of face perception.

  Frontiers in human neuroscience 20100101

• Pivotal role of anterior cingulate cortex in working memory after traumatic brain injury in youth.

  Frontiers in neurology 20100101

• Hemispheric Asymmetries during Processing of Immoral Stimuli.

  Frontiers in evolutionary neuroscience 20100101

• Severe chronic urticaria treated with oral mini-pulse steroid therapy.

  Indian journal of dermatology 20100101

• Fluticasone furoate nasal spray: Profile of an enhanced-affinity corticosteroid in treatment of seasonal allergic rhinitis.

  Journal of asthma and allergy 20100101

• Update on the management of chronic eczema: new approaches and emerging treatment options.

  Clinical, cosmetic and investigational dermatology 20100101

• N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a 'chemical knock-out equivalent' to assess the impact of efflux transporters on oral drug absorption in the rat.

  Journal of pharmaceutical sciences 20091201

• Analysis of drug interactions involving fruit beverages and organic anion-transporting polypeptides.

  Journal of clinical pharmacology 20091201

• Effects of the P-glycoprotein inducer carbamazepine on fexofenadine pharmacokinetics.

  Therapeutic drug monitoring 20091201

• Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis.

  Asian Pacific journal of allergy and immunology 20091201

• Temperature-dependent specific transport of levofloxacin in human intestinal epithelial LS180 cells.

  Biopharmaceutics & drug disposition 20091101

• Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study.

  Pediatric pulmonology 20091101

• Neural activation of swallowing and swallowing-related tasks in healthy young adults: an attempt to separate the components of deglutition.

  Human brain mapping 20091001

• Expression of histamine H4 receptor in human epidermal tissues and attenuation of experimental pruritus using H4 receptor antagonist.

  The Journal of toxicological sciences 20091001

• ESRD impairs nonrenal clearance of fexofenadine but not midazolam.

  Journal of the American Society of Nephrology : JASN 20091001

• Comparing the stimulant effects of the H1-antagonist fexofenadine with 2 psychostimulants, modafinil and methylphenidate.

  Journal of clinical psychopharmacology 20091001

• Impact of OATP transporters on pharmacokinetics.

  British journal of pharmacology 20091001

• Uptake/efflux transport of tramadol enantiomers and O-desmethyl-tramadol: focus on P-glycoprotein.

  Basic & clinical pharmacology & toxicology 20090901

• The role of transporters in the pharmacokinetics of orally administered drugs.

  Pharmaceutical research 20090901

• Structural determinants for histamine H(1) affinity, hERG affinity and QTc prolongation in a series of terfenadine analogs.

  Bioorganic & medicinal chemistry letters 20090901

• Recent advances in bone marrow biopsy pathology.

  Journal of hematopathology 20090901

• [Antihistamines in the treatment of allergic rhinitis--update 2008/2009].

  Otolaryngologia polska = The Polish otolaryngology 20090901

• The representation of abstract task rules in the human prefrontal cortex.

  Cerebral cortex (New York, N.Y. : 1991) 20090801

• Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.

  Pharmaceutical research 20090801

• Ureteral stones due to systemic mastocytosis: diagnostic and therapeutic characteristics.

  Urological research 20090801

• Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.

  The Journal of pharmacy and pharmacology 20090801

• The occurrence of antihistamines in sewage waters and in recipient rivers.

  Environmental science and pollution research international 20090701

• The neural correlates of social attention: automatic orienting to social and nonsocial cues.

  Psychological research 20090701

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  Pharmaceutical research 20090701

• [Antipruritic efficacy of a high-dosage antihistamine therapy. Results of a retrospectively analysed case series].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20090701

• Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders.

  Expert opinion on drug metabolism & toxicology 20090701

• The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output.

  PLoS pathogens 20090701

• Allergies in India: a study on medication compliance.

  Journal of the Indian Medical Association 20090701

• Pharmacokinetic drug interaction between fexofenadine and fluvastatin mediated by organic anion-transporting polypeptides in rats.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

• Influence of the G2677T/C3435T haplotype of MDR1 on P-glycoprotein trafficking and ibutilide-induced block of HERG.

  The pharmacogenomics journal 20090601

• Short-term effect of quercetin on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein, in healthy volunteers.

  European journal of clinical pharmacology 20090601

• Effects of pranlukast hydrate on airway hyperresponsiveness in non-asthmatic patients with Japanese cedar pollinosis.

  Allergology international : official journal of the Japanese Society of Allergology 20090601

• Costs of second-generation antihistamines in the treatment of allergic rhinitis: US perspective.

  Current medical research and opinion 20090601

• Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 cases.

  The Journal of dermatology 20090601

• Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090601

• Synthesis and structure-activity relationships of phenothiazine carboxylic acids having pyrimidine-dione as novel histamine H(1) antagonists.

  Bioorganic & medicinal chemistry letters 20090515

• Relationship between airborne pollen count and treatment outcome in Japanese cedar pollinosis patients.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20090501

• A dual role for prediction error in associative learning.

  Cerebral cortex (New York, N.Y. : 1991) 20090501

• Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.

  Drug and alcohol dependence 20090501

• A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.

  Clinical therapeutics 20090501

• Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil.

  British journal of clinical pharmacology 20090501

• Multiple H1-antihistamine-induced urticaria.

  The Journal of dermatology 20090401

• Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approach.

  Journal of medicinal chemistry 20090326

• The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine.

  Drug metabolism and disposition: the biological fate of chemicals 20090301

• Fexofenadine brain exposure and the influence of blood-brain barrier P-glycoprotein after fexofenadine and terfenadine administration.

  Drug metabolism and disposition: the biological fate of chemicals 20090301

• Update on prescription and over-the-counter histamine inverse agonists in rhinitis therapy.

  Current allergy and asthma reports 20090301

• Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir.

  Anesthesiology 20090301

• Safety and efficacy of desloratadine in chronic idiopathic urticaria in clinical practice: an observational study of 9246 patients.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090301

• Psychoactive medication and traffic safety.

  International journal of environmental research and public health 20090301

• Activity in face-responsive brain regions is modulated by invisible, attended faces: evidence from masked priming.

  Cerebral cortex (New York, N.Y. : 1991) 20090101

• Common cortical loci are activated during visuospatial interpolation and orientation discrimination judgements.

  PloS one 20090101

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  Molecular pharmaceutics 20090101

• IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model.

  International archives of allergy and immunology 20090101

• The brightness of colour.

  PloS one 20090101

• The concept of receptor occupancy to predict clinical efficacy: a comparison of second generation H1 antihistamines.

  Allergy and asthma proceedings 20090101

• Influence of epinastine hydrochloride, an H1-receptor antagonist, on the function of mite allergen-pulsed murine bone marrow-derived dendritic cells in vitro and in vivo.

  Mediators of inflammation 20090101

• Exploring BOLD changes during spatial attention in non-stimulated visual cortex.

  PloS one 20090101

• Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy.

  Allergy and asthma proceedings 20090101

• Erythropoietin over-expression protects against diet-induced obesity in mice through increased fat oxidation in muscles.

  PloS one 20090101

• Exploration of the one-bead one-compound methodology for the design of prolyl oligopeptidase substrates.

  PloS one 20090101

• Mutant glycyl-tRNA synthetase (Gars) ameliorates SOD1(G93A) motor neuron degeneration phenotype but has little affect on Loa dynein heavy chain mutant mice.

  PloS one 20090101

• Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit.

  Journal of investigational allergology & clinical immunology 20090101

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  PloS one 20090101

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  The American journal of Chinese medicine 20090101

• Gout. Novel therapies for treatment of gout and hyperuricemia.

  Arthritis research & therapy 20090101

• The impact of socioeconomic status on the neural substrates associated with pleasure.

  The open neuroimaging journal 20090101

• Interactions between herbal medicines and prescribed drugs: an updated systematic review.

  Drugs 20090101

• Bioequivalence of fexofenadine tablet formulations assessed in healthy Iranian volunteers.

  Arzneimittel-Forschung 20090101

• Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics.

  Journal of biological engineering 20090101

• Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.

  Molecular pharmaceutics 20090101

• Current use and potential role of bevacizumab in the treatment of gastrointestinal cancers.

  Biologics : targets & therapy 20090101

• Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy.

  BMC cancer 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Efficacy of repeated pretreatment with olopatadine hydrochloride on rhinitis induced by intranasal instillation of toluene-2,4-diisocyanate in rats.

  Pharmacology 20090101

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  PloS one 20090101

• A structure filter for the Eukaryotic Linear Motif Resource.

  BMC bioinformatics 20090101

• Quantifying and resolving multiple vector transformants in S. cerevisiae plasmid libraries.

  BMC biotechnology 20090101

• Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis.

  PloS one 20090101

• Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.

  Drugs 20090101

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  PloS one 20090101

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  PloS one 20090101

• From uncertainty to reward: BOLD characteristics differentiate signaling pathways.

  BMC neuroscience 20090101

• The anti-inflammatory effects of levocetirizine--are they clinically relevant or just an interesting additional effect?

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20090101

• Olopatadine in chronic idiopathic urticaria.

  Indian journal of dermatology 20090101

• Chronic urticaria and treatment options.

  Indian journal of dermatology 20090101

• Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.

  Journal of investigational allergology & clinical immunology 20090101

• Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis.

  Journal of toxicology 20090101

• Further evidence for aberrant prefrontal salience coding in schizophrenia.

  Frontiers in behavioral neuroscience 20090101

• Chronic autoimmune urticaria: where we stand?

  Indian journal of dermatology 20090101

• Psoriasis vulgaris and digestive system disorders: is there a linkage?

  Folia histochemica et cytobiologica 20090101

• Fast Dissolving Tablets of Fexofenadine HCl by Effervescent Method.

  Indian journal of pharmaceutical sciences 20090101

• Prescription writing trends of antihistamines at the university health centre.

  Indian journal of pharmaceutical sciences 20090101

• Leukotriene receptor antagonists in monotherapy or in combination with antihistamines in the treatment of chronic urticaria: a systematic review.

  Journal of asthma and allergy 20090101

• Once daily levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria.

  Journal of asthma and allergy 20090101

• Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines.

  Journal of asthma and allergy 20090101

• The temporal dynamics of voluntary emotion regulation.

  PloS one 20090101

• QTc prolongation assessment in anticancer drug development: clinical and methodological issues.

  Ecancermedicalscience 20090101

• Task-dependent modulation of medial geniculate body is behaviorally relevant for speech recognition.

  Current biology : CB 20081209

• Hemispheric asymmetry of frequency-dependent suppression in the ipsilateral primary motor cortex during finger movement: a functional magnetic resonance imaging study.

  Cerebral cortex (New York, N.Y. : 1991) 20081201

• Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Design, data analysis, and simulation of in vitro drug transport kinetic experiments using a mechanistic in vitro model.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Transient receptor potential vanilloid-1-mediated calcium responses are inhibited by the alkylamine antihistamines dexbrompheniramine and chlorpheniramine.

  Experimental lung research 20081201

• Narrowband ultraviolet B phototherapy is beneficial in antihistamine-resistant symptomatic dermographism: a pilot study.

  Journal of the American Academy of Dermatology 20081101

• Potential benefit from an H1-receptor antagonist on postexercise syncope in the heat.

  Medicine and science in sports and exercise 20081101

• Validation of the use of nonnaive surgically catheterized rats for pharmacokinetics studies.

  Journal of the American Association for Laboratory Animal Science : JAALAS 20081101

• Frequency-specific coupling in the cortico-cerebellar auditory system.

  Journal of neurophysiology 20081001

• Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis.

  Therapeutics and clinical risk management 20081001

• Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities.

  Clinical pharmacology and therapeutics 20081001

• Age-dependent changes in the neural correlates of force modulation: an fMRI study.

  Neurobiology of aging 20080901

• Relative contribution of absorptive and secretory transporters to the intestinal absorption of fexofenadine in rats.

  International journal of pharmaceutics 20080901

• Salmeterol with fluticasone enhances the suppression of IL-8 release and increases the translocation of glucocorticoid receptor by human neutrophils stimulated with cigarette smoke.

  Journal of molecular medicine (Berlin, Germany) 20080901

• Effect of allergic rhinitis on the use and cost of health services by children with asthma.

  Yonsei medical journal 20080830

• Selective activation around the left occipito-temporal sulcus for words relative to pictures: individual variability or false positives?

  Human brain mapping 20080801

• Probenecid, but not cystic fibrosis, alters the total and renal clearance of fexofenadine.

  Journal of clinical pharmacology 20080801

• Non-sedating antihistamines in the treatment of chronic idiopathic urticaria using patient-reported outcomes.

  Current medical research and opinion 20080801

• Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude.

  Aviation, space, and environmental medicine 20080801

• A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma--application to preclinical pharmacokinetics.

  Talanta 20080715

• Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.

  Archives of dermatological research 20080701

• The effects of fexofenadine at steady-state on sleep architecture: a study using polysomnography in healthy Korean volunteers.

  Expert opinion on pharmacotherapy 20080701

• Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.

  PLoS biology 20080701

• Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

  Journal of medicinal chemistry 20080612

• Factors that predict early treatment failure for patients with locally advanced (T4) breast cancer.

  British journal of cancer 20080603

• Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.

  Molecular pharmacology 20080501

• Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.

  Drug metabolism and disposition: the biological fate of chemicals 20080501

• The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers.

  British journal of clinical pharmacology 20080501

• Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies.

  Drug metabolism and disposition: the biological fate of chemicals 20080501

• Voxel-based cortical thickness measurements in MRI.

  NeuroImage 20080501

• Intact cell binding for in vitro prediction of sedative and non-sedative histamine H1-receptor antagonists based on receptor internalization.

  Journal of pharmacological sciences 20080501

• Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080501

• Investigation of the inhibitory effects of various drugs on the hepatic uptake of fexofenadine in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20080401

• Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.

  Methods and findings in experimental and clinical pharmacology 20080401

• A fatal outcome in a patient with glioblastoma multiforme after receiving high-dose methotrexate.

  Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20080301

• Optimizing antibiotic selection in treating COPD exacerbations.

  International journal of chronic obstructive pulmonary disease 20080301

• Determination of levocetirizine in human plasma by liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080201

• Fexofenadine in pediatrics: oral tablet and suspension formulations.

  Expert opinion on pharmacotherapy 20080201

• Effect of Ginkgo biloba extract on lopinavir, midazolam and fexofenadine pharmacokinetics in healthy subjects.

  Current medical research and opinion 20080201

• Rasagiline in treatment of Parkinson's disease.

  Neuropsychiatric disease and treatment 20080201

• Isolation and structure elucidation of photodegradation products of fexofenadine.

  Journal of pharmaceutical and biomedical analysis 20080122

• Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.

  Journal of pharmaceutical and biomedical analysis 20080122

• Multidrug resistance-associated protein 2 is primarily responsible for the biliary excretion of fexofenadine in mice.

  Drug metabolism and disposition: the biological fate of chemicals 20080101

• Fexofenadine downmodulates antigen-presenting ability of murine epidermal Langerhans cells.

  Journal of dermatological science 20080101

• Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.

  Pulmonary pharmacology & therapeutics 20080101

• Using FMRI brain activation to identify cognitive states associated with perception of tools and dwellings.

  PloS one 20080101

• Phonological processing of ignored distractor pictures, an fMRI investigation.

  BMC neuroscience 20080101

• Distinct roles for lateral and medial rostral prefrontal cortex in source monitoring of perceived and imagined events.

  Neuropsychologia 20080101

• Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.

  Clinical pharmacokinetics 20080101

• Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.

  Clinical drug investigation 20080101

• Enhanced detection of gametocytes by magnetic deposition microscopy predicts higher potential for Plasmodium falciparum transmission.

  Malaria journal 20080101

• Labetalol infusion for refractory hypertension causing severe hypotension and bradycardia: an issue of patient safety.

  Patient safety in surgery 20080101

• Fast visuomotor processing of redundant targets: the role of the right temporo-parietal junction.

  PloS one 20080101

• Clinical drugs that interact with St. John's wort and implication in drug development.

  Current pharmaceutical design 20080101

• Pharmacokinetics, safety and tolerability of an oral suspension of fexofenadine for children with allergic rhinitis.

  Allergy and asthma proceedings 20080101

• Optimizing bioavailability of oral administration of small peptides through pharmacokinetic and pharmacodynamic parameters: the effect of water and timing of meal intake on oral delivery of Salmon Calcitonin.

  BMC clinical pharmacology 20080101

• Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test.

  Indian journal of dermatology, venereology and leprology 20080101

• Loratadine provides early symptom control in seasonal allergic rhinitis.

  Allergy and asthma proceedings 20080101

• The problems of meta-analysis for antibiotic treatment of chronic obstructive pulmonary disease, a heterogeneous disease: a commentary on Puhan et al.

  BMC medicine 20080101

• Neural basis of self and other representation in autism: an FMRI study of self-face recognition.

  PloS one 20080101

• The apical uptake transporter of levofloxacin is distinct from the peptide transporter in human intestinal epithelial Caco-2 cells.

  Drug metabolism and pharmacokinetics 20080101

• Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry.

  Drug metabolism letters 20080101

• Fexofenadine hydrochloride in the treatment of allergic disease: a review.

  Journal of asthma and allergy 20080101

• Alternative and improved method for the simultaneous determination of fexofenadine and pseudoephedrine in their combined tablet formulation.

  Journal of pharmaceutical and biomedical analysis 20071221

• Antihistamine and sodium cromoglycate medication for food cold water exercise-induced anaphylaxis.

  Allergy 20071201

• Small-scale, semi-automated purification of eukaryotic proteins for structure determination.

  Journal of structural and functional genomics 20071201

• [Linear dermatitis due to shiitake mushrooms].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20071201

• Two cases of alopecia areata responsive to fexofenadine.

  The Journal of dermatology 20071201

• Safety and tolerability of fexofenadine hydrochloride, 15 and 30 mg, twice daily in children aged 6 months to 2 years with allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071201

• Receptor-induced thiolate couples Env activation to retrovirus fusion and infection.

  PLoS pathogens 20071201

• Laser ablation electrospray ionization for atmospheric pressure, in vivo, and imaging mass spectrometry.

  Analytical chemistry 20071101

• Sleep-related hippocampo-cortical interplay during emotional memory recollection.

  PLoS biology 20071101

• An information theoretic characterisation of auditory encoding.

  PLoS biology 20071101

• Fexofenadine/cyclodextrin inclusion complexation: phase solubility, thermodynamic, physicochemical, and computational analysis.

  Drug development and industrial pharmacy 20071101

• Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015

• Letrozole in advanced breast cancer: the PO25 trial.

  Breast cancer research and treatment 20071001

• Readout from iconic memory and selective spatial attention involve similar neural processes.

  Psychological science 20071001

• Suppressive activity of fexofenadine hydrochloride on nitric oxide production in-vitro and in-vivo.

  The Journal of pharmacy and pharmacology 20071001

• Safety and tolerability of fexofenadine for the treatment of allergic rhinitis in children 2 to 5 years old.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20071001

• [Acute onset Hodgkin's disease following Lyell's syndrome].

  Annales de dermatologie et de venereologie 20071001

• T cells contain an RNase-insensitive inhibitor of APOBEC3G deaminase activity.

  PLoS pathogens 20070901

• Potential therapeutic applications of hyaluronan in the lung.

  International journal of chronic obstructive pulmonary disease 20070901

• Perigenual anterior cingulate morphology covaries with perceived social standing.

  Social cognitive and affective neuroscience 20070901

• Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• Face adaptation aftereffects reveal anterior medial temporal cortex role in high level category representation.

  NeuroImage 20070801

• Formaldehyde-induced urticarial vasculitis.

  The Australasian journal of dermatology 20070801

• Blockade of brain histamine metabolism alters methamphetamine-induced expression pattern of stereotypy in mice via histamine H1 receptors.

  Neuroscience 20070713

• Neural representation of auditory size in the human voice and in sounds from other resonant sources.

  Current biology : CB 20070703

• Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis.

  International journal of colorectal disease 20070701

• Bioequivalence of two fexofenadine formulations in healthy human volunteers after single oral administration.

  Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601

• Montelukast in the management of allergic rhinitis.

  Therapeutics and clinical risk management 20070601

• Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.

  Clinical pharmacology and therapeutics 20070401

• Review of azelastine nasal spray in the treatment of allergic and non-allergic rhinitis.

  Expert opinion on pharmacotherapy 20070401

• Attentional load modulates responses of human primary visual cortex to invisible stimuli.

  Current biology : CB 20070320

• Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys.

  Drug metabolism and disposition: the biological fate of chemicals 20070301

• Intestinal drug transporter expression and the impact of grapefruit juice in humans.

  Clinical pharmacology and therapeutics 20070301

• Pharmacokinetics of fexofenadine enantiomers in healthy subjects.

  Chirality 20070301

• Host ABCE1 is at plasma membrane HIV assembly sites and its dissociation from Gag is linked to subsequent events of virus production.

  Traffic (Copenhagen, Denmark) 20070301

• Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.

  Biological & pharmaceutical bulletin 20070301

• Adenosine in inflammatory joint diseases.

  Purinergic signalling 20070301

• Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer.

  International journal of pharmaceutics 20070207

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  NeuroImage 20070201

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  Pharmaceutical research 20070201

• Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.

  Biomedical chromatography : BMC 20070201

• Simple and reliable HPLC analysis of fexofenadine hydrochloride in tablets and its application to dissolution studies.

  Die Pharmazie 20070201

• The effect of fexofenadine hydrochloride on productivity and quality of life in patients with chronic idiopathic urticaria.

  Cutis 20070201

• Determination of fexofenadine enantiomers in human plasma with high-performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20070117

• Effect of standard medication on quality of life of patients with atopic dermatitis.

  The Journal of dermatology 20070101

• Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.

  Journal of investigational allergology & clinical immunology 20070101

• False occurrences of functional motifs in protein sequences highlight evolutionary constraints.

  BMC bioinformatics 20070101

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  Allergy and asthma proceedings 20070101

• Exacerbations of chronic obstructive pulmonary disease: when are antibiotics indicated? A systematic review.

  Respiratory research 20070101

• Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum.

  Journal of AOAC International 20070101

• Changing human visual field organization from early visual to extra-occipital cortex.

  PloS one 20070101

• Correlations between Diffusion Tensor Imaging (DTI) and Magnetic Resonance Spectroscopy (1H MRS) in schizophrenic patients and normal controls.

  BMC psychiatry 20070101

• A new paradigm in respiratory hygiene: modulating respiratory secretions to contain cough bioaerosol without affecting mucus clearance.

  BMC pulmonary medicine 20070101

• Corpus callosum morphology in capuchin monkeys is influenced by sex and handedness.

  PloS one 20070101

• Some pharmacokinetic aspects of the lipophilic terfenadine and zwitterionic fexofenadine in humans.

  Drugs in R&D 20070101

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  PloS one 20070101

• Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review.

  Allergy and asthma proceedings 20070101

• Desloratadine for chronic idiopathic urticaria: a review of clinical efficacy.

  American journal of clinical dermatology 20070101

• Dissociation of neural correlates of verbal and non-verbal visual working memory with different delays.

  Behavioral and brain functions : BBF 20070101

• Medicinal importance of grapefruit juice and its interaction with various drugs.

  Nutrition journal 20070101

• Ets-1 confers cranial features on neural crest delamination.

  PloS one 20070101

• Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice.

  Respiratory research 20070101

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  Otolaryngologia polska = The Polish otolaryngology 20070101

• A feature-selective independent component analysis method for functional MRI.

  International journal of biomedical imaging 20070101

• Challenge-driven attention: interacting frontal and brainstem systems.

  Frontiers in human neuroscience 20070101

• Bimanual passive movement: functional activation and inter-regional coupling.

  Frontiers in integrative neuroscience 20070101

• The proarrhythmic antihistaminic drug terfenadine increases spontaneous calcium release in human atrial myocytes.

  European journal of pharmacology 20061228

• H1 and H2 receptors mediate postexercise hyperemia in sedentary and endurance exercise-trained men and women.

  Journal of applied physiology (Bethesda, Md. : 1985) 20061201

• In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphisms.

  Pharmacogenetics and genomics 20061201

• Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.

  European annals of allergy and clinical immunology 20061201

• The CML-related oncoprotein BCR/ABL induces expression of histidine decarboxylase (HDC) and the synthesis of histamine in leukemic cells.

  Blood 20061115

• Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine.

  Drug metabolism and disposition: the biological fate of chemicals 20061101

• Inhibitory effect of carboxylic acid group on hERG binding.

  Bioorganic & medicinal chemistry letters 20061101

• Treatment of allergic rhinitis can improve blood pressure control.

  Journal of human hypertension 20061101

• Grapefruit juice and drug interactions. Exploring mechanisms of this interaction and potential toxicity for certain drugs.

  Geriatrics 20061101

• New antihistamines: a critical view.

  Jornal de pediatria 20061101

• Ultrarush venom desensitization after systemic reactions during conventional venom immunotherapy.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101

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  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101

• [The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101

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  European journal of pharmacology 20061010

• QT interval prolongation and beyond.

  Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 20061001

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  PLoS medicine 20061001

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  Arerugi = [Allergy] 20061001

• Silicon switches of marketed drugs.

  Mini reviews in medicinal chemistry 20061001

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  Clinical therapeutics 20061001

• Effects of single and multiple doses of itraconazole on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

  British journal of clinical pharmacology 20060901

• Altered oral bioavailability and pharmacokinetics of P-glycoprotein substrates by coadministration of biochanin A.

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• Membrane transporter proteins: a challenge for CNS drug development.

  Dialogues in clinical neuroscience 20060901

• Hepatobiliary disposition of a drug/metabolite pair: Comprehensive pharmacokinetic modeling in sandwich-cultured rat hepatocytes.

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• Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.

  British journal of clinical pharmacology 20060801

• Oral antihistamine therapy influences plasma tryptase levels in adult atopic dermatitis.

  Journal of dermatological science 20060801

• Alteration of fexofenadine disposition in the rat isolated perfused liver following injection of bacterial lipopolysaccharide.

  Clinical and experimental pharmacology & physiology 20060801

• Transporter-mediated intestinal absorption of fexofenadine in rats.

  Drug metabolism and pharmacokinetics 20060801

• A combined neurophysiological and behavioural study into the stimulating effects of fexofenadine on performance.

  Journal of psychopharmacology (Oxford, England) 20060701

• First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.

  Drug metabolism and disposition: the biological fate of chemicals 20060701

• Stimulating effects of the antihistamine fexofenadine: testing the dopamine transporter hypothesis.

  Psychopharmacology 20060701

• Time-dependent interaction between lopinavir/ritonavir and fexofenadine.

  Journal of clinical pharmacology 20060701

• Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects.

  Current medical research and opinion 20060701

• In vivo use of the P450 inactivator 1-aminobenzotriazole in the rat: varied dosing route to elucidate gut and liver contributions to first-pass and systemic clearance.

  Journal of pharmaceutical sciences 20060601

• Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060601

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• [Is MDR 1 gene a key to successful chemotherapy?].

  Ginekologia polska 20060601

• Antimuscarinic actions of antihistamines on the heart.

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• Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid.

  Drug metabolism and disposition: the biological fate of chemicals 20060501

• Effect of P-glycoprotein on intestinal absorption and brain penetration of antiallergic agent bepotastine besilate.

  Drug metabolism and disposition: the biological fate of chemicals 20060501

• Once-daily immediate-release fexofenadine and sustained-release pseudoephedrine combination: a new treatment option for allergic rhinitis.

  Expert opinion on pharmacotherapy 20060501

• Effects of itraconazole and diltiazem on the pharmacokinetics of fexofenadine, a substrate of P-glycoprotein.

  British journal of clinical pharmacology 20060501

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  Clinical and experimental dermatology 20060501

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  Arerugi = [Allergy] 20060501

• Fexofenadine in horses: pharmacokinetics, pharmacodynamics and effect of ivermectin pretreatment.

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  PLoS biology 20060401

• A gradient HPLC test procedure for the determination of impurities and the synthetic precursors in 2-[4-(1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl)-phenyl]-2-methylpropionic acid.

  Journal of chromatographic science 20060401

• Effect of pretreatment with fexofenadine on the safety of immunotherapy in patients with allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401

• MDR- and CYP3A4-mediated drug-herbal interactions.

  Life sciences 20060327

• The cutaneous rabbit illusion affects human primary sensory cortex somatotopically.

  PLoS biology 20060301

• The effect of short- and long-term administration of verapamil on the disposition of cytochrome P450 3A and P-glycoprotein substrates.

  Clinical pharmacology and therapeutics 20060301

• Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060201

• Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.

  International journal of clinical pharmacology and therapeutics 20060201

• Fexofenadine, an H1-receptor antagonist, partially but rapidly inhibits the itch of contact dermatitis induced by diphenylcyclopropenone in patients with alopecia areata.

  The Journal of dermatology 20060201

• Changes in pH differently affect the binding properties of histamine H1 receptor antagonists.

  European journal of pharmacology 20060120

• Differential effects of fexofenadine on arachidonic acid metabolism in cultured human monocytes.

  Pharmacology 20060101

• Reduced responsiveness is an essential feature of chronic fatigue syndrome: a fMRI study.

  BMC neurology 20060101

• On systems and control approaches to therapeutic gain.

  BMC cancer 20060101

• The role of antihistamines in asthma management.

  Treatments in respiratory medicine 20060101

• Levocetirizine: a review of its use in the management of allergic rhinitis and skin allergies.

  Drugs 20060101

• In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.

  Drugs in R&D 20060101

• Stimulating effects of H1-antagonists.

  Current pharmaceutical design 20060101

• Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis.

  Allergy and asthma proceedings 20060101

• Saliva secretion in patients with allergic rhinitis.

  International archives of allergy and immunology 20060101

• Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.

  The European journal of general practice 20060101

• Simultaneous quantification of fexofenadine and pseudoephedrine in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: method development, validation and application to a clinical study.

  Rapid communications in mass spectrometry : RCM 20060101

• New evidence of H1-receptor independent COX-2 inhibition by fexofenadine HCl in vitro.

  Pharmacology 20060101

• fMRI-compatible rehabilitation hand device.

  Journal of neuroengineering and rehabilitation 20060101

• The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis.

  The Journal of international medical research 20060101

• Standardization and performance evaluation of mononuclear cell cytokine secretion assays in a multicenter study.

  BMC immunology 20060101

• Selecting the optimal oral antihistamine for patients with allergic rhinitis.

  Drugs 20060101

• Policy adjustment in a dynamic economic game.

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• Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937.

  BMC cancer 20060101

• [Treatment of allergic rhinitis associated with hypothyroidism].

  Vestnik otorinolaringologii 20060101

• Effect of olopatadine and other histamine H1 receptor antagonists on the skin inflammation induced by repeated topical application of oxazolone in mice.

  Pharmacology 20051201

• Treatment for allergic rhinitis and chronic idiopathic urticaria: focus on oral antihistamines.

  The Annals of pharmacotherapy 20051201

• The methanol disolvate and the dihydrate of fexofenadine, an antihistamine drug.

  Acta crystallographica. Section C, Crystal structure communications 20051201

• Neural substrate of body size: illusory feeling of shrinking of the waist.

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• The efficacy and safety of 30 mg fexofenadine HCl bid in pediatric patients with allergic rhinitis.

  Asian Pacific journal of allergy and immunology 20051201

• Management of persistent allergic rhinitis: evidence-based treatment with levocetirizine.

  Therapeutics and clinical risk management 20051201

• Antipruritic effect of the single oral administration of German chamomile flower extract and its combined effect with antiallergic agents in ddY mice.

  Journal of ethnopharmacology 20051003

• Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20051001

• Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.

  Pharmacology 20051001

• Effects of fexofenadine and hydroxyzine on brake reaction time during car-driving with cellular phone use.

  Human psychopharmacology 20051001

• Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051001

• Case report: occupationally related recurrent varicella (chickenpox) in a hospital nurse.

  Environmental health perspectives 20051001

• Treatment of ear pain in pilots in flight.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051001

• The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.

  The Journal of dermatology 20051001

• [Wheat anaphylaxis enhanced by administration of acetylsalicylic acid or by exercise].

  Arerugi = [Allergy] 20051001

• Binding and repression of translation of the cognate mRNA by Trichinella spiralis thymidylate synthase differ from the corresponding interactions of the human enzyme.

  The Biochemical journal 20050915

• Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.

  Current medical research and opinion 20050901

• Addition of fexofenadine to inhaled corticosteroid therapy to reduce inflammatory biomarkers in atopic asthma.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050901

• Determination of fexofenadine in tablets by capillary electrophoresis in free solution and in solution with cyclodextrins as analyte carriers.

  Drug development and industrial pharmacy 20050901

• Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901

• Development and validation of dissolution tests for fexofenadine hydrochloride capsules and coated tablets.

  Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050811

• Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability.

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• Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.

  Journal of the American Academy of Nurse Practitioners 20050801

• Effect of itraconazole on the pharmacokinetics and pharmacodynamics of fexofenadine in relation to the MDR1 genetic polymorphism.

  Clinical pharmacology and therapeutics 20050801

• The advantages of the Ussing chamber in drug absorption studies.

  Journal of biomolecular screening 20050801

• Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.

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• Enantioselective analysis of cetirizine in pharmaceuticals by cyclodextrin-mediated capillary electrophoresis.

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• Review of H1 antihistamines in the treatment of chronic idiopathic urticaria.

  Cutis 20050801

• P-glycoprotein plays a major role in the efflux of fexofenadine in the small intestine and blood-brain barrier, but only a limited role in its biliary excretion.

  Drug metabolism and disposition: the biological fate of chemicals 20050701

• Effect of loratadine on mouse models of atopic dermatitis associated pruritus.

  International immunopharmacology 20050701

• Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration.

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• A treatment for allergic rhinitis: a view on the role of levocetirizine.

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• Once-daily fexofenadine treatment for chronic idiopathic urticaria: a multicenter, randomized, double-blind, placebo-controlled study.

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• Treating intermittent allergic rhinitis: a prospective, randomized, placebo and antihistamine-controlled study of Butterbur extract Ze 339.

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• Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1).

  British journal of clinical pharmacology 20050501

• Single-dose and steady-state bioequivalence of fexofenadine and pseudoephedrine combination tablets compared with individual formulations in healthy adults.

  Current medical research and opinion 20050501

• Preferential downmodulation of certain chemokines by fexofenadine in human keratinocytes.

  Journal of dermatological science 20050401

• The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050401

• H1 receptor-mediated vasodilatation contributes to postexercise hypotension.

  The Journal of physiology 20050301

• CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations.

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• Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides.

  Clinical pharmacology and therapeutics 20050301

• Effect of fruit juices on the oral bioavailability of fexofenadine in rats.

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• Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season.

  International archives of allergy and immunology 20050201

• Evaluation of ER, PgR, HER-2 and Ki-67 as predictors of response to neoadjuvant anthracycline chemotherapy for operable breast cancer.

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• Comparative anticholinergic activities of 10 histamine H1 receptor antagonists in two functional models.

  European journal of pharmacology 20050104

• Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.

  Journal of clinical pharmacology 20050101

• Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitis.

  Drugs 20050101

• Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics.

  Clinical pharmacology and therapeutics 20050101

• Second-generation antihistamines: actions and efficacy in the management of allergic disorders.

  Drugs 20050101

• Pruritic urticarial papules and plaques of pregnancy presenting in the postpartum period: a case report.

  The Journal of reproductive medicine 20050101

• Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport.

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• Minimal important difference (MID) of the Dermatology Life Quality Index (DLQI): results from patients with chronic idiopathic urticaria.

  Health and quality of life outcomes 20050101

• Folate system correlations in DNA microarray data.

  BMC cancer 20050101

• Cost and utilization impacts of oral antihistamines in the California Medi-Cal program.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101

• In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine.

  BMC pharmacology 20050101

• Comparative effects of fexofenadine and montelukast on allergen-induced wheal and flare.

  Allergy and asthma proceedings 20050101

• Chiral cardiovascular drugs: an overview.

  American journal of therapeutics 20050101

• Capillary electrophoresis method for fexofenadine hydrochloride in capsules.

  Journal of AOAC International 20050101

• ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal.

  Cancer cell international 20050101

• Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, 5-12 hours postdose, in the environmental exposure unit.

  Allergy and asthma proceedings 20050101

• The effect of fexofenadine on expression of intercellular adhesion molecule 1 and induction of apoptosis on peripheral eosinophils.

  Allergy and asthma proceedings 20050101

• Cheilitis glandularis in an African-American woman: response to antibiotic therapy.

  Skinmed 20050101

• Case studies: Use of salicylic acid (Avosil) and hydrogel (Avogel) in limiting scar formation.

  Journal of burns and wounds 20050101

• The utility of mixed-effects covariate analysis in rapid selection of doses in pediatric subjects: a case study with fexofenadine hydrochloride.

  Biopharmaceutics & drug disposition 20041201

• Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor.

  International archives of allergy and immunology 20041201

• Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041201

• Suppressive activity of fexofenadine hydrochloride on metalloproteinase production from nasal fibroblasts in vitro.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041201

• Microbial oxidation of terfenadine and ebastine into fexofenadine and carebastine.

  Bioorganic & medicinal chemistry letters 20041101

• A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.

  Clinical pharmacology and therapeutics 20041101

• Current concepts and therapeutic strategies for allergic rhinitis in school-age children.

  Clinical therapeutics 20041101

• Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding.

  Pharmacology 20041001

• Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.

  Clinical and experimental dermatology 20040901

• Venom immunotherapy: adverse reactions and treatment failure.

  Current opinion in allergy and clinical immunology 20040801

• Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.

  Journal of clinical pharmacology 20040801

• Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.

  Fundamental & clinical pharmacology 20040801

• Validation of the Dermatology Life Quality Index as an outcome measure for urticaria-related quality of life.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801

• Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040801

• A novel membrane sensor for histamine H1-receptor antagonist 'fexofenadine'.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040801

• Transport characteristics of fexofenadine in the Caco-2 cell model.

  Pharmaceutical research 20040801

• Determination of fexofenadine in human plasma using 96-well solid phase extraction and HPLC with tandem mass spectrometric detection.

  Journal of pharmaceutical and biomedical analysis 20040629

• Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detection.

  Journal of pharmaceutical and biomedical analysis 20040629

• Effects of single or combined histamine H1-receptor and leukotriene CysLT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis.

  British journal of clinical pharmacology 20040601

• Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20040601

• Pharmacokinetic interactions of drugs with St John's wort.

  Journal of psychopharmacology (Oxford, England) 20040601

• A dynamic system model-based technique for functional MRI data analysis.

  NeuroImage 20040501

• Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates.

  Basic & clinical pharmacology & toxicology 20040501

• [Effects between the first-and second-generation histamine H1-antagonists on seizure development of pentylenetetrazole-induced kindling in rats].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040501

• Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040501

• Repeated dosing effects of mediator antagonists in inhaled corticosteroid-treated atopic asthmatic patients.

  Chest 20040401

• A placebo-controlled evaluation of butterbur and fexofenadine on objective and subjective outcomes in perennial allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401

• Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401

• Lack of association between fexofenadine and rhabdomyolysis.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040401

• Mizolastine and fexofenadine modulate cytokine pattern after nasal allergen challenge.

  European annals of allergy and clinical immunology 20040401

• Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro.

  International archives of allergy and immunology 20040301

• The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis.

  International immunopharmacology 20040301

• Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040301

• Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidence.

  International journal of clinical pharmacology and therapeutics 20040301

• Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human.

  The Journal of pharmacology and experimental therapeutics 20040201

• The effects of butterbur on the histamine and allergen cutaneous response.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040201

• Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.

  Managed care interface 20040201

• Herbal modulation of P-glycoprotein.

  Drug metabolism reviews 20040201

• Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.

  Current medical research and opinion 20040101

• Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.

  The Journal of dermatological treatment 20040101

• Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040101

• Cetirizine: a review of its use in allergic disorders.

  Drugs 20040101

• Evaluation of the utilization patterns of leukotriene modifiers in a large managed care health plan.

  Journal of managed care pharmacy : JMCP 20040101

• [Treatment of solar urticaria by intravenous immunoglobulins and PUVA therapy].

  Annales de dermatologie et de venereologie 20040101

• Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis.

  Allergy and asthma proceedings 20040101

• Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines.

  Allergy and asthma proceedings 20040101

• The MDR1 (ABCB1) gene polymorphism and its clinical implications.

  Clinical pharmacokinetics 20040101

• Identification of allergic disease among users of antihistamines.

  Journal of managed care pharmacy : JMCP 20040101

• Fingersomatotopy in area 3b: an fMRI-study.

  BMC neuroscience 20040101

• Safety and tolerability of treatments for allergic rhinitis in children.

  Drug safety 20040101

• Suppressive activity of fexofenadine hydrochloride on the production of eosinophil chemoattractants from human nasal fibroblasts in vitro.

  Arzneimittel-Forschung 20040101

• Mechanisms underlying fatigue: a voxel-based morphometric study of chronic fatigue syndrome.

  BMC neurology 20040101

• Development and validation of a liquid chromatographic method for fexofenadine hydrochloride in capsules.

  Journal of AOAC International 20040101

• Chronic urticaria: aetiology, management and current and future treatment options.

  Drugs 20040101

• Fexofenadine HCl 60 mg/ pseudoephedrine HCl 120 mg has a 60-minute onset of action in the treatment of seasonal allergic rhinitis symptoms, as assessed in an allergen exposure unit.

  Allergy and asthma proceedings 20040101

• [Serum sICAM-1 in patients suffering from allergic rhinitis treated with fexofenadine or fluticasone].

  Pneumonologia i alergologia polska 20040101

• Actual therapeutic management of allergic and hyperreactive nasal disorders.

  GMS current topics in otorhinolaryngology, head and neck surgery 20040101

• Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers.

  Human psychopharmacology 20031201

• Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.

  Clinical pharmacology and therapeutics 20031101

• The effects of fruit juices on drug disposition: a new model for drug interactions.

  European journal of clinical investigation 20031101

• A study comparing the inhibitory effects of single and repeated oral doses of ebastine and fexofenadine against histamine-induced skin reactivity.

  International archives of allergy and immunology 20031101

• Effect of the second-generation antihistamine, fexofenadine, on cough reflex sensitivity and pulmonary function.

  British journal of clinical pharmacology 20031101

• Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine.

  The Journal of dermatology 20031101

• Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment.

  The Journal of allergy and clinical immunology 20031001

• Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules.

  The Journal of allergy and clinical immunology 20031001

• Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.

  The Journal of allergy and clinical immunology 20031001

• Prospects for antihistamines in the treatment of asthma.

  The Journal of allergy and clinical immunology 20031001

• Is 3-mm less drowsiness important?

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

• Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001

• Rapid assessment of P-glycoprotein inhibition and induction in vitro.

  Pharmaceutical research 20030801

• Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801

• The effects of fexofenadine on reaction time, decision-making, and driver behavior.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801

• Randomized, double-masked comparison of olopatadine ophthalmic solution, mometasone furoate monohydrate nasal spray, and fexofenadine hydrochloride tablets using the conjunctival and nasal allergen challenge models.

  Clinical therapeutics 20030801

• Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing.

  Allergy 20030601

• Supplementation of fexofenadine therapy with nedocromil sodium 2% ophthalmic solution to treat ocular symptoms of seasonal allergic conjunctivitis.

  Clinical & experimental ophthalmology 20030601

• H1-antihistaminic activity of cetirizine and fexofenadine in allergic children.

  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20030601

• Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study.

  The British journal of dermatology 20030601

• Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030601

• [Medicinal drugs and automobile driving ability].

  Therapeutische Umschau. Revue therapeutique 20030601

• [Clinical aspects of anti-inflammatory action of antihistamines].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601

• [Safety of new antihistamines].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601

• Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.

  Bioorganic & medicinal chemistry letters 20030519

• First do no harm: managing antihistamine impairment in patients with allergic rhinitis.

  The Journal of allergy and clinical immunology 20030501

• High dose cetirizine: a case report.

  Cutis 20030501

• Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501

• A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cognitive and psychomotor function related to driving a car.

  Clinical therapeutics 20030501

• Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis.

  The Journal of allergy and clinical immunology 20030401

• Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis.

  The Journal of allergy and clinical immunology 20030401

• The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030401

• [H1 histamine antagonists].

  Revue medicale de Bruxelles 20030401

• Spectrophotometric determination of binary mixtures of pseudoephedrine with some histamine H1-receptor antagonists using derivative ratio spectrum method.

  Journal of pharmaceutical and biomedical analysis 20030326

• Decongestant effects of antihistamines: a class effect?

  The Journal of allergy and clinical immunology 20030301

• Solar urticaria induced by infrared radiation.

  Clinical and experimental dermatology 20030301

• Effect of fexofenadine hydrochloride on cedar pollinosis.

  Auris, nasus, larynx 20030201

• Failure of cetirizine and fexofenadine to prevent motion sickness.

  The Annals of pharmacotherapy 20030201

• The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.

  British journal of clinical pharmacology 20030201

• Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.

  The Journal of allergy and clinical immunology 20030201

• The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.

  Aviation, space, and environmental medicine 20030201

• Why aren't lower, effective, OTC doses available earlier by prescription?

  The Annals of pharmacotherapy 20030101

• Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.

  Clinical pharmacology and therapeutics 20030101

• Internal standard signal suppression by co-eluting analyte in isotope dilution LC-ESI-MS.

  The Analyst 20030101

• Chronic urticaria: a role for newer immunomodulatory drugs?

  American journal of clinical dermatology 20030101

• [Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030101

• Dapsone induced cholangitis as a part of dapsone syndrome: a case report.

  BMC gastroenterology 20030101

• Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.

  BMC family practice 20030101

• Antihistamines in the treatment of dermatitis.

  Journal of cutaneous medicine and surgery 20030101

• Evaluation of a combination of a unani pharmacopeal preparation (itrifal ustukhudoos) with cloves (qaranfal) in allergic rhinitis - a preliminary clinical study.

  Ancient science of life 20030101

• Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.

  Life sciences 20021220

• Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists.

  The American journal of medicine 20021216

• Treatment of allergic rhinitis.

  The American journal of medicine 20021216

• Comparative pharmacology of H1 antihistamines: clinical relevance.

  The American journal of medicine 20021216

• Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80.

  Journal of dermatological science 20021201

• Facial swelling and eosinophilia in a 44-year-old woman.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201

• Effects of fexofenadine on the early response to nasal allergen challenge.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021201

• Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells.

  Asian journal of andrology 20021201

• Sea transport of animal and vegetable oils and its environmental consequences.

  Marine pollution bulletin 20021201

• The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.

  British journal of pharmacology 20021101

• Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir.

  Journal of clinical pharmacology 20021101

• Clinical pharmacology of H1-antihistamines in the skin.

  The Journal of allergy and clinical immunology 20021101

• Determination of some histamine H1-receptor antagonists in dosage forms.

  Journal of pharmaceutical and biomedical analysis 20021015

• Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021001

• Review of fexofenadine in the treatment of chronic idiopathic urticaria.

  International journal of dermatology 20021001

• The use of handheld computers in clinical trials.

  Controlled clinical trials 20021001

• Simultaneous determination of fexofenadine and its related compounds by HPLC.

  Journal of pharmaceutical and biomedical analysis 20020720

• Chronic urticaria and angioedema.

  The New England journal of medicine 20020718

• Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020701

• Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness.

  The Journal of allergy and clinical immunology 20020701

• Onset of action, efficacy, and safety of fexofenadine 60 mg/pseudoephedrine 120 mg versus placebo in the Atlanta allergen exposure unit.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020701

• Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge.

  Clinical therapeutics 20020701

• In vivo anti-inflammatory effects of fexofenadine in chronic idiopathic urticaria.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20020701

• Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.

  Circulation 20020618

• Are herbal products dietary supplements or drugs? An important question for public safety.

  Clinical pharmacology and therapeutics 20020601

• Effect of St John's wort on the pharmacokinetics of fexofenadine.

  Clinical pharmacology and therapeutics 20020601

• Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates.

  Pharmaceutical research 20020601

• The Rx-to-OTC switch of Claritin, Allegra, and Zyrtec: an unprecedented FDA response to petitioners and the protection of public health.

  The American University law review 20020601

• Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2.

  Hepatology (Baltimore, Md.) 20020501

• MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

  British journal of clinical pharmacology 20020501

• Evaluation of cytokines in nasal secretions after nasal antigen challenge: lack of influence of antihistamines.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020501

• [Hay fever and asthma. Many of your patients have both].

  MMW Fortschritte der Medizin 20020425

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• [Chronic idiopathic urticaria: effectiveness of fexofenadine. A double-blind, placebo controlled study with 21 patients].

  Praxis 20020410

• Comparison of five new antihistamines (H1-receptor antagonists) in patients with allergic rhinitis using nasal provocation studies and skin tests.

  Allergy 20020401

• A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20020201

• Are antihistamines useful in managing asthma?

  Current opinion in allergy and clinical immunology 20020201

• Determination of fexofenadine in human plasma and urine by liquid chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020125

• Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.

  Drug metabolism and disposition: the biological fate of chemicals 20020101

• Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

  Clinical pharmacology and therapeutics 20020101

• Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.

  Clinical pharmacokinetics 20020101

• [Comparative antihistamine and anti-allergic effects of various antihistamine preparations].

  Terapevticheskii arkhiv 20020101

• A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101

• An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020101

• Photosensitivity disorders: cause, effect and management.

  American journal of clinical dermatology 20020101

• Potential cardiac toxicity of H1-antihistamines.

  Clinical allergy and immunology 20020101

• H1-antihistamines in children.

  Clinical allergy and immunology 20020101

• 24-hour efficacy of once-daily desloratadine therapy in patients with seasonal allergic rhinitis [ISRCTN32042139].

  BMC family practice 20020101

• Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.

  Rapid communications in mass spectrometry : RCM 20020101

• Urticaria to cetirizine.

  Journal of investigational allergology & clinical immunology 20020101

• The use of antihistamines in safety-critical jobs: a meeting report.

  Current medical research and opinion 20020101

• Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.

  Drugs under experimental and clinical research 20020101

• Evaluation of the efficacy and safety of fexofenadine in the management of chronic idiopathic urticaria: a prospective study with 512 patients.

  Indian journal of dermatology, venereology and leprology 20020101

• Fexofenadine reduces nasal congestion in perennial allergic rhinitis.

  Allergy 20011101

• The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.

  The American journal of managed care 20011001

• Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.

  Modern healthcare 20010806

• Identification of functionally variant MDR1 alleles among European Americans and African Americans.

  Clinical pharmacology and therapeutics 20010801

• Management of Peyronie's disease--a review.

  World journal of urology 20010801

• Safety of fexofenadine in children treated for seasonal allergic rhinitis.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010701

• Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997.

  European journal of clinical pharmacology 20010701

• [Seasonal allergic rhinitis. Nasal obstruction can also beh improved].

  MMW Fortschritte der Medizin 20010503

• Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol.

  American journal of respiratory and critical care medicine 20010501

• Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.

  International archives of allergy and immunology 20010501

• A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.

  The American journal of managed care 20010501

• Newer antihistamines.

  The Medical letter on drugs and therapeutics 20010430

• Uptake and efflux of the peptidic delta-opioid receptor agonist.

  Neuroscience letters 20010406

• Twenty-four hours of activity of cetirizine and fexofenadine in the skin.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010401

• Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors.

  Journal of immunology (Baltimore, Md. : 1950) 20010315

• Skin concentrations of H1-receptor antagonists.

  The Journal of allergy and clinical immunology 20010301

• The effect of rifampin administration on the disposition of fexofenadine.

  Clinical pharmacology and therapeutics 20010301

• Fexofenadine hydrochloride--a new anti-histaminic drug.

  The Israel Medical Association journal : IMAJ 20010301

• Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.

  Clinical therapeutics 20010301

• A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans.

  International journal of clinical pharmacology and therapeutics 20010301

• Fixed solar urticaria to visible light successfully treated with fexofenadine.

  Photodermatology, photoimmunology & photomedicine 20010201

• Multicenter study of the efficacy and safety of fexofenadine 60 mg. twice daily in 108 Thai patients with chronic idiopathic urticaria.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010201

• Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.

  Archives of dermatology 20010101

• Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010101

• Safety of antihistamines in children.

  Drug safety 20010101

• Histamine-induced activation of human lung macrophages.

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