842-07-9 | Sudan i

Packsize	Purity	Availability	Price	Discounted Price
25g	95%	in stock	$12.00	$8.00
100g	95%	in stock	$20.00	$14.00

Description

• Catalog Number: AI56914
• Chemical Name: Sudan i
• CAS Number: 842-07-9
• Molecular Formula: C16H12N2O
• Molecular Weight: 248.2793
• MDL Number: MFCD00003911
• SMILES: Oc1ccc2c(c1/N=N/c1ccccc1)cccc2

Computed Properties

• Complexity: 312
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 4.1

Literature

• Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo.

  Toxicology 20160217

• Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.

  International journal of molecular sciences 20150101

• Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions.

  Toxicology 20140406

• Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I).

  Chemical research in toxicology 20130218

• Solubilization of two organic dyes by cationic ester-containing gemini surfactants.

  Journal of colloid and interface science 20120615

• Selective solid-phase extraction of Sudan I in chilli sauce by single-hole hollow molecularly imprinted polymers.

  Journal of agricultural and food chemistry 20120111

• Molecularly imprinted polymer coated solid-phase microextraction fibers for determination of Sudan I-IV dyes in hot chili powder and poultry feed samples.

  Journal of chromatography. A 20120106

• Molecularly imprinted microspheres as SPE sorbent for selective extraction of four Sudan dyes in catsup products.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111001

• Molecularly imprinted solid-phase extraction combined with ultrasound-assisted dispersive liquid-liquid microextraction for the determination of four Sudan dyes in sausage samples.

  The Analyst 20110621

• Rational design and application of molecularly imprinted sol-gel polymer for the electrochemically selective and sensitive determination of Sudan I.

  Talanta 20110415

• A monoclonal antibody-based immunosensor for detection of Sudan I using electrochemical impedance spectroscopy.

  Talanta 20110315

• Metabolic influences for mutation induction curves after exposure to Sudan-1 and para red.

  Mutagenesis 20100701

• Quantification of (15)N-nitrate in urine with gas chromatography combustion isotope ratio mass spectrometry to estimate endogenous NO production.

  Analytical chemistry 20100115

• Determination of para red, Sudan dyes, canthaxanthin, and astaxanthin in animal feeds using UPLC.

  Journal of chromatographic science 20100101

• Development and validation of a confirmatory HPLC method for simultaneous determination of Sudan dyes in animal tissues and eggs.

  Journal of chromatographic science 20100101

• [Selection of the optimal method of extraction and determination of dye Sudan I-IV and Para Red by high-performance liquid chromatography].

  Voprosy pitaniia 20100101

• Rapid determination of banned Sudan I in foodstuffs using a mesoporous SiO2 modified electrode.

  Journal of AOAC International 20100101

• Mechanism of formation of (deoxy)guanosine adducts derived from peroxidase-catalyzed oxidation of the carcinogenic nonaminoazo dye 1-phenylazo-2-hydroxynaphthalene (Sudan I).

  Chemical research in toxicology 20091101

• Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study.

  Interdisciplinary toxicology 20090901

• Determining the adulteration of spices with Sudan I-II-II-IV dyes by UV-visible spectroscopy and multivariate classification techniques.

  Talanta 20090815

• Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli.

  Protein expression and purification 20090801

• Development of enzyme-linked immunosorbent assays for Sudan dyes in chilli powder, ketchup and egg yolk.

  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090601

• Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole.

  Interdisciplinary toxicology 20081201

• A one-electron oxidation of carcinogenic nonaminoazo dye Sudan I by horseradish peroxidase.

  Neuro endocrinology letters 20081001

• Experimental approaches to evaluate activities of cytochromes P450 3A.

  Interdisciplinary toxicology 20080901

• Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2.

  Interdisciplinary toxicology 20080901

• [Synthesis of Sudan I artificial antigen].

  Wei sheng yan jiu = Journal of hygiene research 20080501

• Inhibition of Sudan I genotoxicity in human liver-derived HepG2 cells by the antioxidant hydroxytyrosol.

  Free radical research 20080201

• Assay of the set of all Sudan azodye (I, II, III, IV, and Para-Red) contaminating agents by liquid chromatography-tandem mass spectrometry and isotope dilution methodology.

  Journal of agricultural and food chemistry 20080109

• The induction of cytochrome P450 1A1 by sudan dyes.

  Journal of biochemical and molecular toxicology 20080101

• A simple 2-directional high-performance thin-layer chromatographic method for the simultaneous determination of curcumin, metanil yellow, and sudan dyes in turmeric, chili, and curry powders.

  Journal of AOAC International 20080101

• [Simultaneous determination of canthaxanthin and Sudan Red in salted duck egg yolk by reversed-phase high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20071101

• Determination of banned 10 azo-dyes in hot chili products by gel permeation chromatography-liquid chromatography-electrospray ionization-tandem mass spectrometry.

  Journal of chromatography. A 20070914

• [Determination of Sudan Red I-IV in duck egg yolk using ultra performance liquid chromatography-tandem mass spectrometry].

  Se pu = Chinese journal of chromatography 20070901

• Development of a new method for analysis of Sudan dyes by pressurized CEC with amperometric detection.

  Electrophoresis 20070601

• Synthesis and characterization of a molecularly imprinted silica gel sorbent for the on-line determination of trace Sudan I in Chilli powder through high-performance liquid chromatography.

  Journal of agricultural and food chemistry 20070516

• Sudan I induces genotoxic effects and oxidative DNA damage in HepG2 cells.

  Mutation research 20070305

• Flow injection chemiluminescence determination of sudan I in hot chilli sauce.

  Journal of agricultural and food chemistry 20070207

• Binding of Sudan II and IV to lecithin liposomes and E. coli membranes: insights into the toxicity of hydrophobic azo dyes.

  BMC structural biology 20070101

• Fast cleanup method for the analysis of Sudan I-IV and para red in various foods and paprika color (oleoresin) by high-performance liquid chromatography/diode array detection: focus on removal of fat and oil as fatty acid methyl esters prepared by transesterification of acylglycerols.

  Journal of AOAC International 20070101

• Direct method for determination of Sudan I in FD&C Yellow No. 6 and D&C Orange No. 4 by reversed-phase liquid chromatography.

  Journal of AOAC International 20070101

• Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5.

  Neuro endocrinology letters 20061201

• Development and optimization of an analytical method for the determination of Sudan dyes in hot chilli pepper by high-performance liquid chromatography with on-line electrogenerated BrO- -luminol chemiluminescence detection.

  Journal of chromatography. A 20060929

• Determination of lycopene and beta-carotene by high-performance liquid chromatography using sudan I as internal standard.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060621

• [Effect of Sudan I, III and IV on proliferation of HepG-2 and SGC-7901].

  Huan jing ke xue= Huanjing kexue 20060601

• Development of a fast analytical method for the determination of sudan dyes in chili- and curry-containing foodstuffs by high-performance liquid chromatography-photodiode array detection.

  Journal of agricultural and food chemistry 20060208

• [Sudan and other illegal dyes--food adulteration].

  Roczniki Panstwowego Zakladu Higieny 20060101

• Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

  Cancer letters 20050408

• In vitro and in vivo metabolism of ethyl 4-[(2-hydroxy-1-naphthyl)azo]benzoate.

  European journal of drug metabolism and pharmacokinetics 20050101

• Determination of 1-phenylazo-2-naphthol (Sudan I) in chilli powder and in chilli-containing food products by GPC clean-up and HPLC with LC/MS confirmation.

  Food additives and contaminants 20041001

• Development and in-house validation of a liquid chromatography-electrospray-tandem mass spectrometry method for the simultaneous determination of Sudan I, Sudan II, Sudan III and Sudan IV in hot chilli products.

  Journal of chromatography. A 20040709

• Fast determination of Sudan I by HPLC/APCI-MS in hot chilli, spices, and oven-baked foods.

  Journal of agricultural and food chemistry 20040225

• Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

  Cancer research 20021015

• Modified short-term guinea pig sensitization tests for detecting contact allergens as an alternative to the conventional test.

  Contact dermatitis 20010301

• Allergic contact dermatitis releases soluble factors that stimulate melanogenesis through activation of protein kinase C-related signal-transduction pathway.

  The Journal of investigative dermatology 19921001

• Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis.

  Toxicology and applied pharmacology 19890101

• Use of rat liver altered focus models for testing chemicals that have completed two-year carcinogenicity studies.

  Toxicologic pathology 19890101