84243-58-3 | Imazodan

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$38.00	$27.00

Description

• Catalog Number: AB46267
• Chemical Name: Imazodan
• CAS Number: 84243-58-3
• Molecular Formula: C13H12N4O
• Molecular Weight: 240.2606
• MDL Number: MFCD00867109
• SMILES: O=C1CCC(=NN1)c1ccc(cc1)n1cncc1

Computed Properties

• Complexity: 347
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 0.7

Literature

• Defining the binding site of levosimendan and its analogues in a regulatory cardiac troponin C-troponin I complex.

  Biochemistry 20080715

• Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model.

  Journal of biomolecular screening 20060801

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Mechanisms of leptin secretion from white adipocytes.

  American journal of physiology. Cell physiology 20020701

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Cardiovascular effects of NSP-804 and NSP-805, novel cardiotonic agents with vasodilator properties.

  Journal of cardiovascular pharmacology 19930601

• 3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.

  Journal of medicinal chemistry 19920221

• Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for the treatment of congestive heart failure.

  Journal of medicinal chemistry 19890201