848821-58-9 | (S)-(-)-Alpha,alpha-diphenyl-2-pyrrolidinemethanol trimethylsilyl ether

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$13.00	$10.00
10g	98%	in stock	$20.00	$14.00
25g	98%	in stock	$50.00	$35.00
100g	98%	in stock	$200.00	$140.00

Description

• Catalog Number: AC15278
• Chemical Name: (S)-(-)-Alpha,alpha-diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
• CAS Number: 848821-58-9
• Molecular Formula: C20H27NOSi
• Molecular Weight: 325.52
• MDL Number: MFCD08690083
• SMILES: C[Si](OC(c1ccccc1)(c1ccccc1)[C@@H]1CCCN1)(C)C

Computed Properties

• Complexity: 348
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5

Upstream Synthesis Route

The (S)-2-(Diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine is a versatile compound widely used in chemical synthesis for its unique properties. This compound serves as an efficient chiral ligand in asymmetric catalysis reactions, effectively promoting the formation of enantiomerically enriched products. Additionally, it can be employed as a key building block in the synthesis of complex organic molecules, enabling the construction of various pharmaceuticals, agrochemicals, and materials with high stereoselectivity. Its ability to control the stereochemistry of reactions makes it a valuable tool for researchers and chemists seeking to access enantiopure compounds for various applications in the field of organic chemistry.

Literature

• Organophosphorus reagents in organocatalysis: synthesis of optically active α-methylene-δ-lactones and δ-lactams.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20120813