864084-88-8 | L-Glutaminyl-L-arginyl-L-phenylalanyl-L-seryl-L-arginine

Packsize	Purity	Availability	Price	Discounted Price
10mg		1 week	$129.00	$90.00
25mg		1 week	$208.00	$145.00
50mg		1 week	$308.00	$215.00

Description

• Catalog Number: AB53524
• Chemical Name: L-Glutaminyl-L-arginyl-L-phenylalanyl-L-seryl-L-arginine
• CAS Number: 864084-88-8
• Molecular Formula: C29H48N12O8
• Molecular Weight: 692.7670
• MDL Number: MFCD09752700
• SMILES: OC[C@@H](C(=O)N[C@H](C(=O)O)CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)N)N)CCCNC(=N)N)Cc1ccccc1

Computed Properties

• Complexity: 1170
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 5
• Heavy Atom Count: 49
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 12
• Rotatable Bond Count: 23
• XLogP3: -7

Literature

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  Regulatory peptides 20121010

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• Systemically active human opiorphin is a potent yet non-addictive analgesic without drug tolerance effects.

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• Human opiorphin is a naturally occurring antidepressant acting selectively on enkephalin-dependent delta-opioid pathways.

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• Experimental priapism is associated with increased oxidative stress and activation of protein degradation pathways in corporal tissue.

  International journal of impotence research 20100101

• The mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway.

  American journal of physiology. Cell physiology 20091001

• Effects and underlying mechanisms of human opiorphin on colonic motility and nociception in mice.

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  The journal of sexual medicine 20090301

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• The opiorphin gene (ProL1) and its homologues function in erectile physiology.

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