869-19-2 | Glycyl-L-leucine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$24.00	$17.00
5g	97%	in stock	$35.00	$25.00
25g	97%	in stock	$134.00	$94.00
100g	97%	in stock	$438.00	$307.00

Description

• Catalog Number: AC14007
• Chemical Name: Glycyl-L-leucine
• CAS Number: 869-19-2
• Molecular Formula: C8H16N2O3
• Molecular Weight: 188.2242
• MDL Number: MFCD00008127
• SMILES: NCC(=O)N[C@H](C(=O)O)CC(C)C

Computed Properties

• Complexity: 192
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: -2.3

Literature

• Morphological and functional alterations of small intestine in chronic pancreatitis.

  JOP : Journal of the pancreas 20120910

• Kinetic analysis for the degradation of glycyl-L-leucine and L-leucyl-glycine in subcritical water.

  Bioscience, biotechnology, and biochemistry 20120101

• Differentiating passive from transporter-mediated uptake by PepT1: a comparison and evaluation of four methods.

  The Journal of surgical research 20110901

• Features, causes and consequences of splanchnic sequestration of amino acid in old rats.

  PloS one 20110101

• Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins.

  BMC biochemistry 20110101

• Development of biodegradable polyurethane scaffolds using amino acid and dipeptide-based chain extenders for soft tissue engineering.

  Journal of biomaterials science. Polymer edition 20100101

• Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

  Nature chemical biology 20090101

• [Evaluation of the role of the peptide transport system in absorption of dipeptides in the rat small intestine in chronic experiments in vivo].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20090101

• [Digestive enzyme activities in rats kept on standard or surplus breast-feeding and on low-protein diet directly after weaning].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20090101

• Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.

  Bioinorganic chemistry and applications 20090101

• Delayed effects of the terms of separation of rat pups from lactating females and low-protein diet on enzyme activity in digestive and non-digestive organs.

  Bulletin of experimental biology and medicine 20080601

• Folded structures of L-leucylglycine oligopeptides and their aggregational behavior in aqueous solution: Raman scattering spectra and proton NMR spin-lattice relaxation studies.

  The journal of physical chemistry. B 20080508

• [Effect of weaning terms and protein deficit in the rat pup nutrition on activities of digestive enzymes].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20080101

• Hexaaqua-cadmium(II) bis-{[N-(2-oxidobenzyl-idene)glycyl-l-leucinato]cuprate(II)} dihydrate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.

  Journal of medicinal chemistry 20060615

• Characterization of Gly-D-Phe, Gly-L-Leu, and D-Phe as affinity ligands to thermolysin.

  Protein expression and purification 20060401

• The yeaS (leuE) gene of Escherichia coli encodes an exporter of leucine, and the Lrp protein regulates its expression.

  FEBS letters 20050829

• Transpeptidation reactions of a specific substrate catalyzed by the Streptomyces R61 DD-peptidase: the structural basis of acyl acceptor specificity.

  Biochemistry 20050802

• Transpeptidation reactions of a specific substrate catalyzed by the streptomyces R61 DD-peptidase: characterization of a chromogenic substrate and acyl acceptor design.

  Biochemistry 20050802

• New triorganotin(IV) derivatives of dipeptides as anti-inflammatory-antimicrobial agents.

  European journal of medicinal chemistry 20050301

• Relationship between protein deficiency in the ration of rats during early ontogeny and function of enzyme systems of digestive and non-digestive organs in adult life.

  Bulletin of experimental biology and medicine 20040701

• Temperature dependent characteristics of intestinal glycyl-L-leucine dipeptidase in boreal zone fish.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031001

• Effect of vilon and epithalon on activity of enzymes in epithelial and subepithelial layers in small intestine of old rats.

  Bulletin of experimental biology and medicine 20021201

• In vitro and in situ evidence for the contribution of Labrasol and Gelucire 44/14 on transport of cephalexin and cefoperazone by rat intestine.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20021101

• Copper(II)- cis, cis-1,3,5-triaminocyclohexane complex-promoted hydrolysis of dipeptides: kinetic, speciation and structural studies.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020901

• hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions.

  The Journal of clinical investigation 19981201