86953-79-9 | 1-Boc-pyrrolidine

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$19.00	$13.00
10g	95%	in stock	$20.00	$14.00
25g	95%	in stock	$39.00	$27.00
100g	95%	in stock	$115.00	$81.00

Description

• Catalog Number: AB57997
• Chemical Name: 1-Boc-pyrrolidine
• CAS Number: 86953-79-9
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.2368
• MDL Number: MFCD00216581
• SMILES: O=C(N1CCCC1)OC(C)(C)C

Computed Properties

• Complexity: 166
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 1.6

Literature

• Ambient temperature zincation of N-Boc pyrrolidine and its solvent dependency.

  Chemical communications (Cambridge, England) 20120528

• Silyl fluoride electrophiles for the enantioselective synthesis of silylated pyrrolidine catalysts.

  The Journal of organic chemistry 20110902

• Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.

  The Journal of organic chemistry 20110805

• Asymmetric deprotonation using s-BuLi or i-PrLi and chiral diamines in THF: the diamine matters.

  Journal of the American Chemical Society 20101103

• Regioselective and stereoselective copper(I)-promoted allylation and conjugate addition of N-Boc-2-lithiopyrrolidine and N-Boc-2-lithiopiperidine.

  The Journal of organic chemistry 20100618

• Catalytic asymmetric synthesis of piperidines from pyrrolidine: concise synthesis of L-733,060.

  Organic letters 20090507

• Solution-phase parallel synthesis of Hsp90 inhibitors.

  Journal of combinatorial chemistry 20090101

• The first example of enamine-Lewis acid cooperative bifunctional catalysis: application to the asymmetric aldol reaction.

  Chemical communications (Cambridge, England) 20080907

• On the two-ligand catalytic asymmetric deprotonation of N-boc pyrrolidine: probing the effect of the stoichiometric ligand.

  The Journal of organic chemistry 20080815

• Enantioselective Pd-catalyzed alpha-arylation of N-Boc-pyrrolidine: the key to an efficient and practical synthesis of a glucokinase activator.

  The Journal of organic chemistry 20080704

• A new sparteine surrogate for asymmetric deprotonation of N-Boc pyrrolidine.

  Organic letters 20080403

• Asymmetric lithiation-substitution of amines involving rearrangement of borates.

  Organic letters 20080103

• A (-)-sparteine-directed highly enantioselective synthesis of boroproline. Solid- and solution-state structure and properties.

  The Journal of organic chemistry 20070803

• Dynamic thermodynamic and dynamic kinetic resolution of 2-lithiopyrrolidines.

  Journal of the American Chemical Society 20060823

• Asymmetric synthesis of enantioenriched (+)-elaeokanine A.

  The Journal of organic chemistry 20060721

• Reactivity series for s-BuLi/diamine-mediated lithiation of N-Boc pyrrolidine: applications in catalysis and lithiation of N-Boc piperidine.

  Chemical communications (Cambridge, England) 20060628

• Enantioselective, palladium-catalyzed alpha-arylation of N-Boc-pyrrolidine.

  Journal of the American Chemical Society 20060322

• Dynamic kinetic resolution of N-Boc-2-lithiopyrrolidine.

  Chemical communications (Cambridge, England) 20050628

• Is the A-ring of sparteine essential for high enantioselectivity in the asymmetric lithiation-substitution of N-Boc-pyrrolidine?

  Journal of the American Chemical Society 20041201

• An experimental and computational study of the enantioselective lithiation of N-Boc-pyrrolidine using sparteine-like chiral diamines.

  Journal of the American Chemical Society 20041201

• Synthesis of (-)-(R)-pyrrolam a and studies on its stability: a caveat on computational methods.

  The Journal of organic chemistry 20040903

• Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.

  Bioorganic & medicinal chemistry letters 20040405

• Synthesis of sparteine-like chiral diamines and evaluation in the enantioselective lithiation-substitution of N-(tert-butoxycarbonyl)pyrrolidine.

  Organic & biomolecular chemistry 20031121

• Conformational control of flexible molecules: design and synthesis of novel chiral 1,5-diaza-cis-decalins.

  The Journal of organic chemistry 20020503

• An experimental and computational investigation of the enantioselective deprotonation of Boc-piperidine.

  Journal of the American Chemical Society 20020306

• Chiral diamines 4: a computational study of the enantioselective deprotonation of Boc-pyrrolidine with an alkyllithium in the presence of a chiral diamine.

  Journal of the American Chemical Society 20010829