AC09586
Packsize | Purity | Availability | Price | Discounted Price | Quantity | |
---|---|---|---|---|---|---|
1g | 95% | in stock | $19.00 | $14.00 | - + |
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*All prices are in USD.
Catalog Number: | AC09586 |
Chemical Name: | 5-Bromo-4-chloro-1h-pyrrolo[2,3-b]pyridine |
CAS Number: | 876343-82-7 |
Molecular Formula: | C7H4BrClN2 |
Molecular Weight: | 231.4771 |
MDL Number: | MFCD11046240 |
SMILES: | Brc1cnc2c(c1Cl)cc[nH]2 |
The synthesis of 5-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine can be achieved through the following steps: 1. Start with a suitable substituted pyrrole such as 3-bromo-4-chloropyrrole. 2. Condense 3-bromo-4-chloropyrrole with a haloacetonitrile, such as bromoacetonitrile, in the presence of a base (e.g., DBU or TEA) to form the desired pyridine ring. This step involves a nucleophilic substitution followed by cyclization. 3. Refine the product by purification through column chromatography or crystallization to achieve the desired purity of 5-bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine. Reagents and conditions must be chosen based on the specifics of the intermediates and desired purity. It might be necessary to protect/deprotect certain functional groups during the synthesis to control the reactivity and to achieve the correct substitution pattern. Final yield and purity might vary based on the steps and conditions employed.