884-74-2 | (Diphenylphosphoryl)methanol

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$126.00	$88.00
1g	98%	in stock	$171.00	$120.00
5g	98%	in stock	$558.00	$391.00
10g	98%	in stock	$946.00	$662.00
25g	98%	in stock	$1,879.00	$1,316.00

Description

• Catalog Number: AB99962
• Chemical Name: (Diphenylphosphoryl)methanol
• CAS Number: 884-74-2
• Molecular Formula: C13H13O2P
• Molecular Weight: 232.2149
• MDL Number: MFCD00087496
• SMILES: OCP(=O)(c1ccccc1)c1ccccc1

Upstream Synthesis Route

Diphenylphosphorylmethanol, also known as DPPM, is a versatile chemical compound that plays a crucial role in chemical synthesis. In the field of organic chemistry, DPPM is commonly used as a ligand in transition metal-catalyzed reactions. Its unique structure containing both a phosphorus and an oxygen atom allows it to coordinate with various metal ions, facilitating complex formation and enabling selective catalytic reactions.One of the key applications of Diphenylphosphorylmethanol in chemical synthesis is its use as a ligand in metal-catalyzed cross-coupling reactions such as the Suzuki-Miyaura and Heck reactions. By forming stable complexes with transition metals like palladium, DPPM helps enhance the efficiency and selectivity of these important transformations, leading to the synthesis of biologically active molecules, pharmaceuticals, and advanced materials.Moreover, Diphenylphosphorylmethanol can also serve as a chiral auxiliary in asymmetric synthesis. Its chirality can influence the stereochemistry of the reaction, allowing for the production of enantiomerically pure compounds with high optical purity. This application is particularly valuable in the pharmaceutical industry, where precise control over molecular handedness is crucial for drug efficacy and safety.Overall, the unique properties of Diphenylphosphorylmethanol make it a valuable tool in modern chemical synthesis, enabling chemists to access a wide range of functionalized molecules and asymmetric building blocks with high efficiency and precision.