90-45-9 | 9-Aminoacridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$7.00	$5.00
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$33.00	$23.00
25g	98%	in stock	$135.00	$95.00
100g	98%	in stock	$497.00	$348.00

Description

• Catalog Number: AH82031
• Chemical Name: 9-Aminoacridine
• CAS Number: 90-45-9
• Molecular Formula: C13H10N2
• Molecular Weight: 194.2319
• MDL Number: MFCD00150520
• SMILES: Nc1c2ccccc2nc2c1cccc2

Computed Properties

• Complexity: 207
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.8

Literature

• Disruption of DNA Damage-Response by Propyl Gallate and 9-Aminoacridine.

  Toxicological sciences : an official journal of the Society of Toxicology 20160601

• Inhibition of the mutagenic effects of N-methyl-N'-nitro-N-nitrosoguanidine and 9-aminoacridine by indenopyridines in the Salmonella typhimurium tester strain 1537 and E. coli.

  Drug and chemical toxicology 20141001

• Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.

  Scientific reports 20140101

• Studies on the inclusion behavior of 9-Aminoacridine into cyclodextrins: spectroscopic and theoretical evidences.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20130215

• Spectroscopic investigation on the interaction of 9-aminoacridine with certain dyes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901

• Promethazine inhibits NMDA-induced currents - new pharmacological aspects of an old drug.

  Neuropharmacology 20120801

• Comparison of cardiolipins from Drosophila strains with mutations in putative remodeling enzymes.

  Chemistry and physics of lipids 20120701

• Investigations on photoinduced interaction of 9-aminoacridine with certain catechols and rutin.

  Journal of fluorescence 20120701

• Lipidomics of intact mitochondria by MALDI-TOF/MS.

  Journal of lipid research 20120701

• Antigenotoxic properties of two newly synthesized β-aminoketones against N-methyl-N'-nitro-N-nitrosoguanidine and 9-aminoacridine-induced mutagenesis.

  Journal of biochemical and molecular toxicology 20120701

• Raman spectroscopy and laser desorption mass spectrometry for minimal destructive forensic analysis of black and color inkjet printed documents.

  Forensic science international 20120610

• 9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma.

  Cancer chemotherapy and pharmacology 20120601

• Photoacoustic and luminescence characterization of nitrogen heterocyclic aromatic UV-MALDI matrices in solution.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601

• 9-Amino-acridinium bis-(pyridine-2,6-dicarboxyl-ato-κ(3)O(2),N,O(6))ferrate(III) tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20120601

• Quinacrine has anticancer activity in breast cancer cells through inhibition of topoisomerase activity.

  International journal of cancer 20120401

• Synthesis and biological evaluation of acridine derivatives as antimalarial agents.

  ChemMedChem 20120401

• The in vitro toxicology of Swedish snus.

  Critical reviews in toxicology 20120401

• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato)zincate(II) trihydrate.

  Acta crystallographica. Section E, Structure reports online 20120401

• MALDI imaging and structural analysis of rat brain lipid negative ions with 9-aminoacridine matrix.

  Analytical chemistry 20120306

• Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition.

  Analytical chemistry 20120221

• Pharmacokinetics and metabolite identification of a novel VEGFR-2 and Src dual inhibitor 6-chloro-2-methoxy-N-(2-methoxybenzyl) acridin-9-amine in rats by liquid chromatography tandem mass spectrometry.

  Talanta 20120130

• Studying the interactions of a platinum(II) 9-aminoacridine complex with proteins and oligonucleotides by ESI-TOF MS.

  Dalton transactions (Cambridge, England : 2003) 20120107

• An investigation on the fluorescence quenching of 9-aminoacridine by certain pyrimidines.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101

• Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.

  American journal of physiology. Cell physiology 20111001

• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)manganate(II) trihydrate.

  Acta crystallographica. Section E, Structure reports online 20111001

• Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.

  Viruses 20111001

• DNA cleavage activity of Fe(II)N4Py under photo irradiation in the presence of 1,8-naphthalimide and 9-aminoacridine: unexpected effects of reactive oxygen species scavengers.

  Inorganic chemistry 20110905

• Protective effects of methanol extracts from Cladonia rangiformis and Umbilicaria vellea against known mutagens sodium azide and 9-aminoacridine.

  Toxicology and industrial health 20110901

• Acridine derivatives as anti-BVDV agents.

  Antiviral research 20110801

• Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

  Journal of medicinal chemistry 20110714

• Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry.

  Analytical and bioanalytical chemistry 20110701

• Quinacrine and 9-amino acridine inhibit B-Z and B-H(l) form DNA conformational transitions.

  DNA and cell biology 20110701

• Continuous flow immobilized enzyme reactor-tandem mass spectrometry for screening of AChE inhibitors in complex mixtures.

  Analytical chemistry 20110701

• A comparative study of fragment screening methods on the p38α kinase: new methods, new insights.

  Journal of computer-aided molecular design 20110701

• Abnormal phospholipids distribution in the prefrontal cortex from a patient with schizophrenia revealed by matrix-assisted laser desorption/ionization imaging mass spectrometry.

  Analytical and bioanalytical chemistry 20110601

• The sequence selectivity of DNA-targeted 9-aminoacridine cisplatin analogues in a telomere-containing DNA sequence.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110601

• Semi-quantitative analyses of metabolic systems of human colon cancer metastatic xenografts in livers of superimmunodeficient NOG mice.

  Analytical and bioanalytical chemistry 20110601

• Exploration of acridine scaffold as a potentially interesting scaffold for discovering novel multi-target VEGFR-2 and Src kinase inhibitors.

  Bioorganic & medicinal chemistry 20110601

• Microscale MALDI imaging of outer-layer lipids in intact egg chambers from Drosophila melanogaster.

  Analytical chemistry 20110515

• Sphingomyelin is more sensitively detectable as a negative ion than phosphatidylcholine: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study using 9-aminoacridine (9-AA) as matrix.

  Rapid communications in mass spectrometry : RCM 20110430

• Structure-activity relationship of acridine derivatives to amyloid aggregation of lysozyme.

  Biochimica et biophysica acta 20110401

• Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents.

  Environmental and molecular mutagenesis 20110301

• Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib.

  Oncotarget 20110301

• 9-Amino-acridinium nitrate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110301

• Proton motive force in Rhodobacter sphaeroides under anaerobic conditions in the dark.

  Current microbiology 20110201

• Use of fluorescence lifetime technology to provide efficient protection from false hits in screening applications.

  Analytical biochemistry 20110201

• Excited state properties of 9-amino acridine surface adsorbed onto αZr-phosphate particles.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110201

• An update on targeted gene repair in mammalian cells: methods and mechanisms.

  Journal of biomedical science 20110101

• Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure.

  PloS one 20110101

• Dry socket: frequency, clinical picture, and risk factors in a palestinian dental teaching center.

  The open dentistry journal 20110101

• Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers.

  Cell communication and signaling : CCS 20110101

• Acridine and acridinones: old and new structures with antimalarial activity.

  The open medicinal chemistry journal 20110101

• MALDI-MS Redox Lipidomics Applied to Human Hair: A First Look.

  International journal of trichology 20110101

• Differential gene expression by RamA in ciprofloxacin-resistant Salmonella Typhimurium.

  PloS one 20110101

• Measurement of the ΔpH and electric field developed across Arabidopsis thylakoids in the light.

  Methods in molecular biology (Clifton, N.J.) 20110101

• A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function.

  PloS one 20110101

• Voltage-dependent and -independent block of α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor channels.

  Journal of neurochemistry 20101201

• Design and synthesis of threading intercalators to target DNA.

  Bioorganic & medicinal chemistry letters 20101201

• Optimization of matrix conditions for the control of MALDI in-source decay of permethylated glycans.

  Analytical chemistry 20101115

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• 9-Aminoacridine peptide derivatives as versatile reporter systems for use in fluorescence lifetime assays.

  Chemical communications (Cambridge, England) 20101007

• Molecular docking studies of selected tricyclic and quinone derivatives on trypanothione reductase of Leishmania infantum.

  Journal of computational chemistry 20101001

• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato)cuprate(II) trihydrate.

  Acta crystallographica. Section E, Structure reports online 20101001

• Mononuclear Fe(II)-N4Py complexes in oxidative DNA cleavage: structure, activity and mechanism.

  Dalton transactions (Cambridge, England : 2003) 20100914

• MALDI-TOF/MS analysis of archaebacterial lipids in lyophilized membranes dry-mixed with 9-aminoacridine.

  Journal of lipid research 20100901

• Mutagenic and antimutagenic effects of hexane extract of some Astragalus species grown in the eastern Anatolia region of Turkey.

  Phytotherapy research : PTR 20100701

• Lipidomic analysis of porcine olfactory epithelial membranes and cilia.

  Lipids 20100701

• Selective desorption/ionization of sulfatides by MALDI-MS facilitated using 9-aminoacridine as matrix.

  Journal of lipid research 20100601

• Significant sensitivity improvements by matrix optimization: a MALDI-TOF mass spectrometric study of lipids from hen egg yolk.

  Chemistry and physics of lipids 20100601

• Bis(9-amino-acridinium) bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)nickelate(II) trihydrate.

  Acta crystallographica. Section E, Structure reports online 20100601

• The surface charge density of plant cell membranes (sigma): an attempt to resolve conflicting values for intrinsic sigma.

  Journal of experimental botany 20100501

• The intact muscle lipid composition of bulls: an investigation by MALDI-TOF MS and 31P NMR.

  Chemistry and physics of lipids 20100201

• Genotoxicity and antigenotoxicity evaluation of non-photoactivated hypericin.

  Phytotherapy research : PTR 20100101

• Host hindrance to HIV-1 replication in monocytes and macrophages.

  Retrovirology 20100101

• Modulation of mdm2 pre-mRNA splicing by 9-aminoacridine-PNA (peptide nucleic acid) conjugates targeting intron-exon junctions.

  BMC cancer 20100101

• Alveolar osteitis: a comprehensive review of concepts and controversies.

  International journal of dentistry 20100101

• Investigation on the Interactions of NiCR and NiCR-2H with DNA.

  Bioinorganic chemistry and applications 20100101

• Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells.

  Molecular neurodegeneration 20100101

• Matrix-assisted laser desorption/ionization imaging mass spectrometry.

  International journal of molecular sciences 20100101

• Phosphatidylcholines and -ethanolamines can be easily mistaken in phospholipid mixtures: a negative ion MALDI-TOF MS study with 9-aminoacridine as matrix and egg yolk as selected example.

  Analytical and bioanalytical chemistry 20091201

• Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on mepacrine-conjugated diaryl sulfide scaffolds.

  ChemMedChem 20091201

• Identification of chemical compounds that induce HIF-1alpha activity.

  Toxicological sciences : an official journal of the Society of Toxicology 20091101

• Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry.

  Bioorganic & medicinal chemistry letters 20091015

• Binding of TCA to the prion protein: mechanism, implication for therapy, and application as probe for complex formation of bio-macromolecules.

  Journal of biomolecular structure & dynamics 20091001

• A kinetic and structural investigation of DNA-based asymmetric catalysis using first-generation ligands.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090921

• Quantitation of the tacrine analogue octahydroaminoacridine in human plasma by liquid chromatography-tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20090908

• A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.

  Bioorganic & medicinal chemistry letters 20090901

• On the role of topoisomerase I in mediating the cytotoxicity of 9-aminoacridine-based anticancer agents.

  Bioorganic & medicinal chemistry letters 20090801

• In situ primary metabolites localization on a rat brain section by chemical mass spectrometry imaging.

  Analytical chemistry 20090701

• Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue.

  Basic & clinical pharmacology & toxicology 20090601

• Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates.

  Bioorganic & medicinal chemistry letters 20090401

• Biological safety of liposome-fullerene consisting of hydrogenated lecithin, glycine soja sterols, and fullerene-C60 upon photocytotoxicity and bacterial reverse mutagenicity.

  Toxicology and industrial health 20090401

• 9-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-kappaB and p53 pathways.

  Oncogene 20090226

• Blockade of NMDA receptor channels by 9-aminoacridine and its derivatives.

  Neuroscience letters 20090213

• Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials.

  Journal of medicinal chemistry 20090122

• Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II.

  European journal of pharmacology 20090114

• 9-Aminoacridine inhibition of HIV-1 Tat dependent transcription.

  Virology journal 20090101

• Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cellular glycerophospholipids enabled by multiplexed solvent dependent analyte-matrix interactions.

  Analytical chemistry 20081001

• New palladium(II) and platinum(II) complexes with 9-aminoacridine: structures, luminiscence, theoretical calculations, and antitumor activity.

  Inorganic chemistry 20080804

• Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent.

  Cell biochemistry and function 20080801

• Antiprion activity of functionalized 9-aminoacridines related to quinacrine.

  Bioorganic & medicinal chemistry 20080715

• Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin.

  Biophysical chemistry 20080601

• Synthesis and biological activity of stable and potent antitumor agents, aniline nitrogen mustards linked to 9-anilinoacridines via a urea linkage.

  Bioorganic & medicinal chemistry 20080515

• Effect of spermine conjugation on the interaction of acridine with alternating purine-pyrimidine oligodeoxyribonucleotides studied by CD, fluorescence and absorption spectroscopies.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401

• Negative ion mode matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis of oligosaccharides using halide adducts and 9-aminoacridine matrix.

  Rapid communications in mass spectrometry : RCM 20080401

• Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation.

  Virology journal 20080101

• Transformation of MCF-10A cells by random mutagenesis with frameshift mutagen ICR191: a model for identifying candidate breast-tumor suppressors.

  Molecular cancer 20080101

• Ultrasonic trapping of microparticles in suspension and reaction monitoring using Raman microspectroscopy.

  Analytical chemistry 20071015

• Modulation of the genotoxicity of bleomycin by amines through noncovalent DNA interactions and alteration of physiological conditions in yeast.

  Mutation research 20071001

• Thermodynamic analysis of binding between drugs and glycosaminoglycans by isothermal titration calorimetry and fluorescence spectroscopy.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071001

• A role of the 9-aminoacridines and their conjugates in a life science.

  Current protein & peptide science 20071001

• The electrochemical behavior and direct determination of tyrosine at a glassy carbon electrode modified with poly (9-aminoacridine).

  Annali di chimica 20071001

• Frameshift mutations produced by 9-aminoacridine in wild-type, uvrA and recA strains of Escherichia coli; specificity within a hotspot.

  Journal of radiation research 20070901

• Identification of an aminoacridine derivative that binds to RNA tetraloops.

  Journal of medicinal chemistry 20070823

• Preparation of magnetite nanocrystals with surface reactive moieties by one-pot reaction.

  Journal of colloid and interface science 20070715

• Unexpected reactivity of the 9-aminoacridine chromophore in guanidylation reactions.

  The Journal of organic chemistry 20070706

• Exciton self-trapping in tetrafluoro-dimethyl-aminoacridine single crystals.

  The Journal of chemical physics 20070621

• [Attempts to reduce drug resistance of bacteria and cancer cells].

  Orvosi hetilap 20070603

• Molecular recognition of DNA by rigid [N]-polynorbornane-derived bifunctional intercalators: synthesis and evaluation of their binding properties.

  Journal of medicinal chemistry 20070517

• Tautomerism of acridin-9-amines substituted at the exocyclic nitrogen atom: spectroscopic investigations and theoretical studies.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070401

• Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds.

  The Journal of general virology 20070401

• A binary matrix for background suppression in MALDI-MS of small molecules.

  Analytical and bioanalytical chemistry 20070301

• Imaging Matrix Assisted Laser Desorption Ionization Mass Spectrometry: a technique to map plant metabolites within tissues at high spatial resolution.

  Journal of experimental botany 20070101

• A real-time fluorescence assay for measuring N-dealkylation.

  Drug metabolism and disposition: the biological fate of chemicals 20070101

• Effectiveness of a honey dressing for healing pressure ulcers.

  Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20070101

• Quantitative detection of metabolites using matrix-assisted laser desorption/ionization mass spectrometry with 9-aminoacridine as the matrix.

  Rapid communications in mass spectrometry : RCM 20070101

• In silico chemical library screening and experimental validation of a novel 9-aminoacridine based lead-inhibitor of human S-adenosylmethionine decarboxylase.

  Journal of chemical information and modeling 20070101

• Analysis of low molecular weight acids by negative mode matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Complexes of Pd(II) and Pt(II) with 9-aminoacridine: reactions with DNA and study of their antiproliferative activity.

  Bioinorganic chemistry and applications 20070101

• Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.

  Drug target insights 20070101

• In vitro and in vivo anti-retroviral activity of the substance purified from the aqueous extract of Chelidonium majus L.

  Antiviral research 20061101

• Isolation and characterization of dominant and recessive IL-3-independent hematopoietic transformants.

  Oncogene 20061026

• Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells.

  Bioorganic & medicinal chemistry letters 20060915

• New peptide conjugates with 9-aminoacridine: synthesis and binding to DNA.

  Journal of peptide science : an official publication of the European Peptide Society 20060701

• Flow cytometric detection of tandem repeat mutations induced by various chemical classes.

  Mutation research 20060625

• Photoinduced intramolecular charge transfer in 9-aminoacridinium derivatives assisted by intramolecular H-bond.

  The journal of physical chemistry. A 20060622

• Synthesis, anti-inflammatory, analgesic and kinase (CDK-1, CDK-5 and GSK-3) inhibition activity evaluation of benzimidazole/benzoxazole derivatives and some Schiff's bases.

  Bioorganic & medicinal chemistry 20060601

• A modified Vibrio harveyi mutagenicity assay based on bioluminescence induction.

  Letters in applied microbiology 20060601

• High-performance liquid chromatography-mass spectrometry-based acetylcholinesterase assay for the screening of inhibitors in natural extracts.

  Journal of chromatography. A 20060421

• PsbS enhances nonphotochemical fluorescence quenching in the absence of zeaxanthin.

  FEBS letters 20060403

• Frameshift mutations induced by four isomeric nitroacridines and their des-nitro counterpart in the lacZ reversion assay in Escherichia coli.

  Environmental and molecular mutagenesis 20060301

• Characterization of a nonphotochemical quenching-deficient Arabidopsis mutant possessing an intact PsbS protein, xanthophyll cycle and lumen acidification.

  Planta 20060201

• Study on the inclusion behavior of p-sulphonatocalix[4]arene with 9-amino-acridine by spectrofluorometric titrations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060201

• Parallel synthesis of 9-aminoacridines and their evaluation against chloroquine-resistant Plasmodium falciparum.

  Bioorganic & medicinal chemistry 20060115

• Mutagenesis.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Cellular delivery of polyheteroaromate-peptide nucleic acid conjugates mediated by cationic lipids.

  Bioconjugate chemistry 20060101

• Rational design and synthesis of a double-stranded DNA-binder library.

  Biopolymers 20060101

• Synergistic interaction between proton pump inhibitors and resistance modifiers: promoting effects of antibiotics and plasmid curing.

  In vivo (Athens, Greece) 20060101

• Acridin-9-yl exchange: a proposal for the action of some 9-aminoacridine drugs.

  Biopolymers 20060101

• An investigation of DNA mismatch repair capacity under normal culture conditions and under conditions of supra-physiological challenge in human CD4+T cell clones from donors of different ages.

  Experimental gerontology 20051201

• Frameshift mutations induced by the acridine mustard ICR-191 in embryos and in the adult gill and hepatopancreas of rpsL transgenic zebrafish.

  Mutation research 20051015

• Induced mutation spectra at the upp locus in Salmonella typhimurium: response of the target gene in the FU assay to mechanistically different mutagens.

  Mutation research 20051015

• Platinum-acridinylthiourea conjugates show cell line-specific cytotoxic enhancement in H460 lung carcinoma cells compared to cisplatin.

  Cancer chemotherapy and pharmacology 20051001

• Fluorescence of acridinic dyes in anionic surfactant solution.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051001

• Acridine derivatives activate p53 and induce tumor cell death through Bax.

  Cancer biology & therapy 20050801

• Excited-state intramolecular charge transfer in 9-aminoacridine derivative.

  The journal of physical chemistry. A 20050714

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Endoreduplication induced in cultured Chinese hamster cells by different anti-topoisomerase II chemicals. Evidence for the essential contribution of the enzyme to chromosome segregation.

  Mutation research 20050404

• Metabolomic analysis of eukaryotic tissue and prokaryotes using negative mode MALDI time-of-flight mass spectrometry.

  Analytical chemistry 20050401

• Studies of the toxicological potential of tripeptides (L-valyl-L-prolyl-L-proline and L-isoleucyl-L-prolyl-L-proline): IX. Evaluation of the mutagenic potential of synthesized L-valyl-L-prolyl-L-proline in the Salmonella-Escherichia coli/microsome, incorporation assay.

  International journal of toxicology 20050101

• Antigenotoxic potential of glucomannan on four model test systems.

  Cell biology and toxicology 20041101

• Ascorbate in thylakoid lumen functions as an alternative electron donor to photosystem II and photosystem I.

  Archives of biochemistry and biophysics 20040901

• Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.

  Bioorganic & medicinal chemistry letters 20040802

• Self-assembling peptide nanotubes from enantiomeric pairs of cyclic peptides with alternating D and L amino acid residues.

  Journal of the American Chemical Society 20040324

• Chloroplast mutations induced by 9-aminoacridine hydrochloride are independent of the plastome mutator in Oenothera.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20040201

• Anti-stress activity of Propionibacterium freudenreichii : identification of a reactivative protein.

  Antonie van Leeuwenhoek 20040101

• A transient product of DNA alkylation can be stabilized by binding localization.

  Journal of the American Chemical Society 20031119

• RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element.

  Biochemistry 20031007

• Determinants of trapping block of N-methyl-d-aspartate receptor channels.

  Journal of neurochemistry 20031001

• Alleviation of mutagenic effects of polycyclic aromatic agents (quinacrine mustard, ICR-191 and ICR-170) by caffeine and pentoxifylline.

  Mutation research 20030929

• Enhancement of plasmid curing by 9-aminoacridine and two phenothiazines in the presence of proton pump inhibitor 1-(2-benzoxazolyl)-3,3,3-trifluoro-2-propanone.

  International journal of antimicrobial agents 20030901

• Aminoglycoside (neomycin) preference is for A-form nucleic acids, not just RNA: results from a competition dialysis study.

  Journal of the American Chemical Society 20030827

• The metabolism of aluminum citrate and biosynthesis of oxalic acid in Pseudomonas fluorescens.

  Current microbiology 20030701

• Study of T-cell signaling by somatic cell mutagenesis and complementation cloning.

  Journal of immunological methods 20030701

• Superior duplex DNA strand invasion by acridine conjugated peptide nucleic acids.

  Journal of the American Chemical Society 20030528

• Changes in [Ca2+]i induced by several glucose transport-enhancing stimuli in rat epitrochlearis muscle.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030501

• On-line monitoring of airborne chemistry in levitated nanodroplets: in situ synthesis and application of SERS-active Ag-Sols for trace analysis by FT-Raman spectroscopy.

  Analytical chemistry 20030501

• Acridine mutagenesis of zebrafish (Danio rerio).

  Mutation research 20030409

• Lipid membrane with low proton permeability.

  Biochimica et biophysica acta 20030401

• Synthesis, characterization, and photophysical studies of new bichromophoric ruthenium(II) complexes.

  Inorganic chemistry 20030310

• 9-Aminoacridine: an efficient reagent to improve human and plant chromosome banding patterns and to standardize chromosome image analysis.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030101

• Analysis of 2-aminoacridone-derivatized complex oligosaccharides using micellar electrokinetic capillary chromatography and laser-induced fluorescence detection.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Interaction of antitumoral 9-aminoacridine drug with DNA and dextran sulfate studied by fluorescence and surface-enhanced Raman spectroscopy.

  Biopolymers 20030101

• Frameshift mutations induced by three classes of acridines in the lacZ reversion assay in Escherichia coli: potency of responses and relationship to slipped mispairing models.

  Environmental and molecular mutagenesis 20030101

• Staggering of subunits in NMDAR channels.

  Biophysical journal 20021201

• Bead injection for surface enhanced Raman spectroscopy: automated on-line monitoring of substrate generation and application in quantitative analysis.

  The Analyst 20021001

• Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay.

  Mutation research 20020619

• Effects of DNA structure on oxopropenylation by the endogenous mutagens malondialdehyde and base propenal.

  Biochemistry 20020416

• Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating.

  Neuron 20020103

• Anacardic acid-mediated changes in membrane potential and pH gradient across liposomal membranes.

  Biochimica et biophysica acta 20020102

• A study of amsalog (CI-921) administered orally on a 5-day schedule, with bioavailability and pharmacokinetically guided dose escalation.

  Cancer chemotherapy and pharmacology 20020101

• Blocker studies of the functional architecture of the NMDA receptor channel.

  Neuroscience and behavioral physiology 20020101

• Cytochrome b(6)f mutation specifically affects thermal dissipation of absorbed light energy in Arabidopsis.

  The Plant journal : for cell and molecular biology 20011101

• Influence of polyamine architecture on the transport and topoisomerase II inhibitory properties of polyamine DNA-intercalator conjugates.

  Journal of medicinal chemistry 20011025

• Potentiation of BCNU cytotoxicity by molecules targeting abasic lesions in DNA.

  Bioorganic & medicinal chemistry 20010701

• A phase I trial of amsalog (CI-921) administered by intravenous infusion using a 5-day schedule.

  Cancer chemotherapy and pharmacology 20010401

• Surface-enhanced Raman and steady fluorescence study of interaction between antitumoral drug 9-aminoacridine and trypsin-like protease related to metastasis processes, guanidinobenzoatase.

  Biopolymers 20010101

• [Extracellular protein of propionic acid bacteria inhibits induced mutation in strains of Salmonella typhimurium].

  Mikrobiologiia 20010101

• Effects of slow clinorotation on lipid contents and proton permeability of thylakoid membranes of pea chloroplasts.

  Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101

• [Synthesis and antibacterial activity of the new 9-aminoacridine, 10,11-dihydro-5H-dibenzo[b,f]azepine, polyfluoro 5,6-dihydro-1,3,5-oxadiazine derivatives].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

• Inhibitors of human immunodeficiency virus integrase.

  Proceedings of the National Academy of Sciences of the United States of America 19930315

• HIV-1 neutralization and tumor cell proliferation inhibition in vitro by simplified analogues of pyrido[4,3,2-mn]thiazolo[5,4-b]acridine marine alkaloids.

  Journal of medicinal chemistry 19920724