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Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity.
Toxicology 20140406
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DNA damage induced by three major metabolites of 1,3-butadiene in human hepatocyte L02 cells.
Mutation research 20120918
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A mechanistic modeling framework for predicting metabolic interactions in complex mixtures.
Environmental health perspectives 20111201
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Kinetics of ethylene and ethylene oxide in subcellular fractions of lungs and livers of male B6C3F1 mice and male fischer 344 rats and of human livers.
Toxicological sciences : an official journal of the Society of Toxicology 20111001
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Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans.
Chemical research in toxicology 20110919
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1,3-Butadiene: Biomarkers and application to risk assessment.
Chemico-biological interactions 20110630
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Stereoselective coupling reaction of dimethylzinc and alkyne toward nickelacycles.
Organic letters 20110506
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1,3-Butadiene: II. Genotoxicity profile.
Critical reviews in toxicology 20101001
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Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene.
Toxicological sciences : an official journal of the Society of Toxicology 20100601
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Mutagenicity of stereochemical configurations of 1,3-butadiene epoxy metabolites in human cells.
Research report (Health Effects Institute) 20100601
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Quantitative investigation on the metabolism of 1,3-butadiene and of its oxidized metabolites in once-through perfused livers of mice and rats.
Toxicological sciences : an official journal of the Society of Toxicology 20100301
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Stereoselective ring expansion of vinyl oxiranes: mechanistic insights and natural product total synthesis.
Angewandte Chemie (International ed. in English) 20100222
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Cob(I)alamin for trapping butadiene epoxides in metabolism with rat S9 and for determining associated kinetic parameters.
Chemical research in toxicology 20090901
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Genotoxicity of 1,3-butadiene and its epoxy intermediates.
Research report (Health Effects Institute) 20090801
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Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the Comet assay.
Mutation research 20090512
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Alternative reagents for chemical noise reduction in liquid chromatography-mass spectrometry using selective ion-molecule reactions.
Journal of the American Society for Mass Spectrometry 20090101
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An efficient and general enantioselective synthesis of sphingosine, phythosphingosine, and 4-substituted derivatives.
Organic letters 20090101
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Evaluation of cancer tests of 1,3-butadiene using internal dose, genotoxic potency, and a multiplicative risk model.
Cancer research 20081001
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Bimetallic dendrimer-encapsulated nanoparticles as catalysts: a review of the research advances.
Chemical Society reviews 20080801
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HPRT mutations in lymphocytes from 1,3-butadiene-exposed workers in China.
Environmental health perspectives 20080201
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Catalytic performance of symmetrical and unsymmetrical sulfur-containing pincer complexes: synthesis and tandem catalytic activity of the first PCS-pincer palladium complex.
Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
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Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues.
Chemico-biological interactions 20070501
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Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats.
Chemico-biological interactions 20070320
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Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites.
Chemico-biological interactions 20070320
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Synthesis of DNA oligodeoxynucleotides containing structurally defined N6-(2-hydroxy-3-buten-1-yl)-adenine adducts of 3,4-epoxy-1-butene.
Chemico-biological interactions 20070320
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Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells.
Chemico-biological interactions 20070320
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Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene.
Chemico-biological interactions 20070320
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N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides.
Chemico-biological interactions 20070320
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Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro.
Chemico-biological interactions 20070320
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Copper-catalyzed rearrangement of vinyl oxiranes.
Journal of the American Chemical Society 20061220
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Palladium-catalyzed DYKAT of butadiene monoepoxide: enantioselective total synthesis of (+)-DMDP, (-)-bulgecinine, and (+)-broussonetine G.
Chemistry (Weinheim an der Bergstrasse, Germany) 20060825
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3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice.
Environmental and molecular mutagenesis 20060101
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Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.
Chemical biology & drug design 20060101
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Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide.
Mutation research 20050801
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Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence.
Biochemistry 20050308
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Regio- and stereoselectivity of the addition of O-, S-, N-, and C-nucleophiles to the beta vinyl oxirane derived from D-glucal.
The Journal of organic chemistry 20041210
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Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells.
Environmental health perspectives 20041101
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Stereospecific uncatalyzed alpha-O-glycosylation and alpha-C-glycosidation by means of a new D-Gulal-derived alpha vinyl oxirane.
The Journal of organic chemistry 20041015
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Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation.
Bioorganic & medicinal chemistry letters 20040906
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DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.
Chemico-biological interactions 20040630
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Characterization of alkyl-cobalamins formed on trapping of epoxide metabolites of 1,3-butadiene.
Journal of separation science 20040501
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Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.
Chemico-biological interactions 20040315
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Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-(14)C]-butadiene.
Chemico-biological interactions 20040315
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Identification and characterization of a series of nucleoside adducts formed by the reaction of 2'-deoxyguanosine and 1,2,3,4-diepoxybutane under physiological conditions.
Chemical research in toxicology 20031201
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Genetic susceptibility, biomarker respones, and cancer.
Mutation research 20031101
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Mutagenic spectrum of butadiene-derived N1-deoxyinosine adducts and N6,N6-deoxyadenosine intrastrand cross-links in mammalian cells.
Chemical research in toxicology 20021201
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New stereoselective beta-glycosylation via a vinyl oxirane derived from D-glucal.
Organic letters 20021017
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Synthesis and characterization of water-soluble hydroxybutenyl cyclomaltooligosaccharides (cyclodextrins).
Carbohydrate research 20020315
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Enantioselective allylation of beta,gamma-unsaturated aldehydes generated via Lewis acid induced rearrangement of 2-vinyloxiranes.
Organic letters 20020110
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Dose-dependent excretion of unconjugated 3-butene-1,2-diol measured in urine with a gc/ms after 1,3-butadiene exposure.
Toxicology mechanisms and methods 20020101
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Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways.
Drug metabolism and disposition: the biological fate of chemicals 20010601
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Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism.
Chemico-biological interactions 20010601
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First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice.
Chemico-biological interactions 20010601
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Physiological modeling of butadiene disposition in mice and rats.
Chemico-biological interactions 20010601
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Development of a preliminary physiologically based toxicokinetic (PBTK) model for 1,3-butadiene risk assessment.
Chemico-biological interactions 20010601
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Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms.
Chemico-biological interactions 20010601
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Advances in the mass spectrometry of hemoglobin adducts: global analysis of the covalent binding of butadiene monoxide.
Chemico-biological interactions 20010601
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A novel DNA adduct, originating from 1,2-epoxy-3,4-butanediol, is the major DNA adduct after exposure to [2,3-(14)C]-1,3-butadiene,[4-(14)C]-1,2-epoxy-3-butane.
Chemico-biological interactions 20010601
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In vitro genotoxicity testing of (1-chloroethenyl)oxirane, a metabolite of beta-chloroprene.
Chemico-biological interactions 20010601
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Synthesis and characterization of oligodeoxynucleotides containing an N1 beta-hydroxyalkyl adduct of 2'-deoxyinosine.
Chemical research in toxicology 20010601
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Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2).
Chemical research in toxicology 20010401
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Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene.
Mutation research 20010125
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Hemoglobin adducts of epoxybutene in workers occupationally exposed to 1,3-butadiene.
Archives of toxicology 20010101
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Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity.
Advances in experimental medicine and biology 20010101
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Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts.
Environmental and molecular mutagenesis 20010101
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1,3-Butadiene oxidation by human myeloperoxidase. Role of chloride ion in catalysis of divergent pathways.
The Journal of biological chemistry 19921005
