-
Am80-GCSF synergizes myeloid expansion and differentiation to generate functional neutrophils that reduce neutropenia-associated infection and mortality.
EMBO molecular medicine 20161101
-
Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.
Scientific reports 20140101
-
Natural and synthetic retinoids afford therapeutic effects on intracerebral hemorrhage in mice.
European journal of pharmacology 20120515
-
Effects of tamibarotene for the treatment of adult T cell leukemia.
Annals of hematology 20120401
-
A112, a tamibarotene dimethylaminoethyl ester, may inhibit human leukemia cell growth more potently than tamibarotene.
Leukemia & lymphoma 20120201
-
Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by down-regulating Th1 and Th17.
Blood 20120105
-
Acitretin, an enhancer of alpha-secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein.
Neuro-degenerative diseases 20120101
-
Tamibarotene: a candidate retinoid drug for Alzheimer's disease.
Biological & pharmaceutical bulletin 20120101
-
[Retinoids as promising treatment for non-alcoholic fatty liver disease].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101
-
Am80 induces neuronal differentiation via increased tropomyosin-related kinase B expression in a human neuroblastoma SH-SY5Y cell line.
Biomedical research (Tokyo, Japan) 20120101
-
Novel antileukemic agents derived from tamibarotene and nitric oxide donors.
Bioorganic & medicinal chemistry letters 20111201
-
All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-delta.
Journal of leukocyte biology 20110801
-
Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620
-
Synthesis and antitumor activity of new retinobenzoic acids.
Chemistry & biodiversity 20110501
-
Oral administration of retinoic acid receptor-alpha/beta-specific ligand Am80 suppresses experimental autoimmune uveoretinitis.
Investigative ophthalmology & visual science 20110301
-
A retinoic acid receptor agonist Am80 rescues neurons, attenuates inflammatory reactions, and improves behavioral recovery after intracerebral hemorrhage in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101
-
Fluorescence spectrometric study on the interaction of tamibarotene with bovine serum albumin.
Luminescence : the journal of biological and chemical luminescence 20110101
-
Extramedullary disease in acute promyelocytic leukemia: two-in-one disease.
Mediterranean journal of hematology and infectious diseases 20110101
-
Toward the development of innovative bifunctional agents to induce differentiation and to promote apoptosis in leukemia: clinical candidates and perspectives.
Journal of medicinal chemistry 20101014
-
Molecular remission in advanced acute promyelocytic leukaemia after treatment with the oral synthetic retinoid Tamibarotene.
British journal of haematology 20101001
-
Am80 induces neuronal differentiation in a human neuroblastoma NH-12 cell line.
International journal of molecular medicine 20100901
-
Convection-enhanced delivery of a synthetic retinoid Am80, loaded into polymeric micelles, prolongs the survival of rats bearing intracranial glioblastoma xenografts.
The Tohoku journal of experimental medicine 20100801
-
Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580.
Oncogene 20100624
-
Disturbance of rapid eye movement sleep in senescence-accelerated mouse prone/8 mice is improved by retinoic acid receptor agonist Am80 (Tamibarotene).
Neuroscience 20100519
-
[Molecular remission induced by gemtuzumab ozogamicin in an elderly patient with relapsed acute promyelocytic leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology 20100401
-
Am80 inhibits stromal cell-derived factor-1-induced chemotaxis in T-cell acute lymphoblastic leukemia cells.
Leukemia & lymphoma 20100301
-
Updates on the treatment of acute promyelocytic leukemia.
Clinical advances in hematology & oncology : H&O 20100201
-
Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms.
Molecular cancer 20100101
-
Disposition of a new tamibarotene prodrug in mice.
Biological & pharmaceutical bulletin 20091201
-
Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.
ChemMedChem 20091101
-
Retinoid ameliorates experimental autoimmune myositis, with modulation of Th cell differentiation and antibody production in vivo.
Arthritis and rheumatism 20091001
-
The ATRA-dependent overexpression of the glutamate transporter EAAC1 requires RARbeta induction.
Biochimica et biophysica acta 20090901
-
Discovery of tetrahydrotetramethylnaphthalene analogs as adult T-cell leukemia cell-selective proliferation inhibitors in a small chemical library constructed based on multi-template hypothesis.
Bioorganic & medicinal chemistry 20090701
-
Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling.
Journal of neurochemistry 20090701
-
Encapsulation of the synthetic retinoids Am80 and LE540 into polymeric micelles and the retinoids' release control.
Journal of controlled release : official journal of the Controlled Release Society 20090619
-
Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis.
The American journal of pathology 20090601
-
Synergistic interactions between the synthetic retinoid tamibarotene and glucocorticoids in human myeloma cells.
Cancer science 20090601
-
Towards retinoid therapy for Alzheimer's disease.
Current Alzheimer research 20090601
-
Chemopreventive effect of 4-[3,5-Bis(trimethylsilyl) benzamido] benzoic acid (TAC-101) on MNU-induced colon carcinogenesis in a rat model.
Anticancer research 20090601
-
Synthetic retinoid Am80 inhibits interaction of KLF5 with RAR alpha through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells.
FEBS letters 20090417
-
The effect of Am-80, a synthetic retinoid, on spinal cord injury-induced motor dysfunction in rats.
Biological & pharmaceutical bulletin 20090201
-
Oral administration of synthetic retinoid Am80 inhibits the development of type 1 diabetes in non-obese diabetic (NOD) mice.
Biological & pharmaceutical bulletin 20090101
-
Anti-adult T-cell leukemia effects of a novel synthetic retinoid, Am80 (Tamibarotene).
Cancer science 20081101
-
PML-RARalpha inhibitors (ATRA, tamibaroten, arsenic troxide) for acute promyelocytic leukemia.
International journal of clinical oncology 20071001
-
[Molecular physiopathology and molecular targeting therapy of leukemia].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070910
-
RARalpha is a regulatory factor for Am-80-induced cell growth inhibition of hematologic malignant cells.
International journal of oncology 20070801
-
Tamibarotene.
Drugs of today (Barcelona, Spain : 1998) 20070801
-
All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling.
Endocrinology 20070301
-
Induction of class II major histocompatibility complex expression in human multiple myeloma cells by retinoid.
Haematologica 20070101
-
4- [3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induced fas expression and activated caspase-3 and -8 in a DLD-1 colon cancer cell line.
In vivo (Athens, Greece) 20070101
-
Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes.
Cancer research 20060915
-
[Therapeutic strategies for patients with relapsed acute promyelocytic leukemia].
[Rinsho ketsueki] The Japanese journal of clinical hematology 20060801
-
[Retinoid therapy for autoimmune diseases].
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20060601
-
Synthetic retinoid Am80 reduces scavenger receptor expression and atherosclerosis in mice by inhibiting IL-6.
Arteriosclerosis, thrombosis, and vascular biology 20060501
-
[Clinical experience with a new synthetic retinoid, tamibarotene (Am-80) for relapsed or refractory acute promyelocytic leukemia].
Gan to kagaku ryoho. Cancer & chemotherapy 20060301
-
Retinoic acid via RARalpha inhibits the expression of 24-hydroxylase in human prostate stromal cells.
Biochemical and biophysical research communications 20051230
-
Synthetic retinoid Am80 suppresses smooth muscle phenotypic modulation and in-stent neointima formation by inhibiting KLF5.
Circulation research 20051125
-
Antimyeloma effects of a novel synthetic retinoid Am80 (Tamibarotene) through inhibition of angiogenesis.
Leukemia 20050601
-
Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death.
Molecular pharmacology 20050501
-
4-[3,5-Bis(trimethylsilyl)benzamido] benzoic acid (TAC-101) induces apoptosis in colon cancer partially through the induction of Fas expression.
In vivo (Athens, Greece) 20050101
-
Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis.
Biochemical pharmacology 20041201
-
A synthetic retinoid Am80 (tamibarotene) rescues the memory deficit caused by scopolamine in a passive avoidance paradigm.
Biological & pharmaceutical bulletin 20041101
-
A novel retinoid, 4-[3,5-bis (trimethylsilyl) benzamido] benzoic acid (TAC-101), induces apoptosis of human ovarian carcinoma cells and shows potential as a new antitumor agent for clear cell adenocarcinoma.
Gynecologic oncology 20040901
-
Design and synthesis of cyclic urea compounds: a pharmacological study for retinoidal activity.
Bioorganic & medicinal chemistry letters 20040816
-
Promyelocytic leukemia retinoid signaling targets regulate apoptosis,tissue factor and thrombomodulin expression.
Haematologica 20040301
-
Modifying effects of 1'-acetoxychavicol acetate (ACA) and the novel synthetic retinoids Re-80, Am-580 and Am-55P in a two-stage carcinogenesis model in female rats.
Toxicologic pathology 20040101
-
Tamibarotene: AM 80, retinobenzoic acid, Tamibaro.
Drugs in R&D 20040101
-
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents].
[Rinsho ketsueki] The Japanese journal of clinical hematology 20031201
-
[Long-term follow up of re-induction with a new synthetic retinoid, Am-80, for relapse of acute promyelocytic leukemia previously treated with all-trans retinoic acid: results of 7 cases from a single institute].
[Rinsho ketsueki] The Japanese journal of clinical hematology 20031101
-
Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions.
Journal of medicinal chemistry 20020801
-
Structure-Activity study of retinoid agonists bearing substituted dicarba-closo-dodecaborane. Relation between retinoidal activity and conformation of two aromatic nuclei.
Bioorganic & medicinal chemistry letters 20010521
-
Inhibition by retinoids of antigen-induced IL-4 production in rat mast cell line RBL-2H3.
Life sciences 20010202
-
On-line immunoaffinity extraction followed by high-performance liquid chromatography and radioimmunoassay for a novel retinobenzoic acid, AM-80, in human plasma.
Journal of immunoassay & immunochemistry 20010101
-
Good prognosis of patients with acute promyelocytic leukemia who achieved second complete remission (CR) with a new retinoid, Am80, after relapse from CR induced by all-trans-retinoic acid.
International journal of hematology 20001201
-
Thyroid hormone regulation of apoptosis induced by retinoic acid in promyeloleukemic HL-60 cells: studies with retinoic acid receptor-specific and retinoid x receptor-specific ligands.
Thyroid : official journal of the American Thyroid Association 20001201
-
Effect of selective IL-6 inhibitor Am-80 on experimental autoimmune encephalomyelitis in DA rats.
Acta pharmacologica Sinica 20001101
-
The effect of Am-80, one of retinoids derivatives on experimental allergic encephalomyelitis in rats.
Life sciences 20000901
-
Effect of Am-80, a retinoid derivative, on 2, 4-dinitrofluorobenzene-induced contact dermatitis in mice.
Pharmacology 20000501
-
Involvement of insulin-like growth factor binding protein-3 in the retinoic acid receptor-alpha-mediated inhibition of hepatocellular carcinoma cell proliferation.
Cancer letters 20000403
-
Therapeutic applications for ligands of retinoid receptors.
Current pharmaceutical design 20000101
-
Effect of Am-80, a synthetic derivative of retinoid, on experimental arthritis in mice.
Pharmacology 19990201
-
Action mechanism of retinoid-synergistic dibenzodiazepines.
Biochemical and biophysical research communications 19970407
-
Re-induction of complete remission with a new synthetic retinoid, Am-80, for relapse of acute promyelocytic leukaemia previously treated with all-trans retinoic acid.
British journal of haematology 19970401
-
Studies on the metabolism and disposition of the new retinoid 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl] benzoic acid. 4th communication: absorption, metabolism, excretion and plasma protein binding in various animals and man.
Arzneimittel-Forschung 19970301
-
Activation of retinoid X receptors induces apoptosis in HL-60 cell lines.
Molecular and cellular biology 19950701
-
The prevention of adipose differentiation of 3T3-L1 cells caused by retinoic acid is elicited through retinoic acid receptor alpha.
Life sciences 19940101
-
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity.
Journal of medicinal chemistry 19881101
-
New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein.
Cancer research 19870701
