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A systematic toxicity evaluation of cephalosporins via transcriptomics in zebrafish and in silico ADMET studies.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180601
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Cardiac safety evaluation in zebrafish and in silico ADME prediction of cephalosporins with an aminothiazoyl ring at the C-7 position.
Toxicology and applied pharmacology 20180515
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Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis.
ACS medicinal chemistry letters 20151210
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Gene expressions changes in bronchial epithelial cells: markers for respiratory sensitizers and exploration of the NRF2 pathway.
Toxicology in vitro : an international journal published in association with BIBRA 20140301
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Double knockout of β-lactamase and cephalosporin acetyl esterase genes from Escherichia coli reduces cephalosporin C decomposition.
Journal of bioscience and bioengineering 20120601
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Struvite precipitation for ammonia nitrogen removal in 7-aminocephalosporanic acid wastewater.
Molecules (Basel, Switzerland) 20120221
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Synthesis and preliminary antimicrobial activities of new arylideneamino-1,3,4-thiadiazole-(thio/dithio)-acetamido cephalosporanic acids.
Molecules (Basel, Switzerland) 20120119
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Overexpression of synthesized cephalosporin C acylase containing mutations in the substrate transport tunnel.
Journal of bioscience and bioengineering 20120101
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A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations.
PloS one 20120101
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Dual-lifetime referencing (DLR): a powerful method for on-line measurement of internal pH in carrier-bound immobilized biocatalysts.
BMC biotechnology 20120101
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Occupational asthma: new low-molecular-weight causal agents, 2000-2010.
Journal of allergy 20120101
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Characteristic features and biotechnological applications of cross-linked enzyme aggregates (CLEAs).
Applied microbiology and biotechnology 20111101
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[Research progress on strain improvement of Acremonium chrysogenum by genetic engineering].
Yi chuan = Hereditas 20111001
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New implications on genomic adaptation derived from the Helicobacter pylori genome comparison.
PloS one 20110101
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Inhibition of Recombinant D-Amino Acid Oxidase from Trigonopsis variabilis by Salts.
Enzyme research 20110101
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[Expression of modified oxidase of D-aminoacids of Trigonopsis variabilis in methylotrophic yeasts Pichia pastoris].
Prikladnaia biokhimiia i mikrobiologiia 20110101
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Substitute technology for reference substances in the analysis of impurities in cefonicid for injection with HPLC using a diode array detector.
Journal of AOAC International 20110101
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Occupational asthma in antibiotic manufacturing workers: case reports and systematic review.
Journal of allergy 20110101
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[Synthesis and characterization of some new rutin and 7-aminocephalosporanic acid derivatives].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101
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Environmentally safe production of 7-ACA by recombinant Acremonium chrysogenum.
Current microbiology 20101201
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Occupational asthma in Korea.
Journal of Korean medical science 20101201
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Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
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Biosynthesis of cephalosporin-C acylase enzyme: optimal media design, purification, and characterization.
Artificial cells, blood substitutes, and immobilization biotechnology 20101001
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Enhancement of glutaryl-7-aminocephalosporanic acid acylase activity of gamma-glutamyltranspeptidase of Bacillus subtilis.
Biotechnology journal 20100801
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A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis D-amino acid oxidase.
New biotechnology 20100227
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Improved cross-linked enzyme aggregates for the production of desacetyl beta-lactam antibiotics intermediates.
Bioresource technology 20100101
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Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst.
Microbial cell factories 20100101
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Protein engineering of penicillin acylase.
Acta naturae 20100101
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Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E. coli.
Protein expression and purification 20081001
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YesT: a new rhamnogalacturonan acetyl esterase from Bacillus subtilis.
Proteins 20080401
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Development of the semi-synthetic penicillins and cephalosporins.
International journal of antimicrobial agents 20080301
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Properties and applications of microbial D-amino acid oxidases: current state and perspectives.
Applied microbiology and biotechnology 20080201
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The stabilizing effects of immobilization in D-amino acid oxidase from Trigonopsis variabilis.
BMC biotechnology 20080101
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Enzymatic synthesis of cephalosporins. The immobilized acylase from Arthrobacter viscosus: a new useful biocatalyst.
Applied microbiology and biotechnology 20071201
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A colorimetric assay for the determination of acetyl xylan esterase or cephalosporin C acetyl esterase activities using 7-amino cephalosporanic acid, cephalosporin C, or acetylated xylan as substrate.
Analytical biochemistry 20071015
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[7-aminocephalosporanic acid induced bronchial asthma in two patients].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20071001
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Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070901
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Construction of recombinant Escherichia coli D11/pMSTO and its use in enzymatic preparation of 7-aminocephalosporanic acid in one pot.
Journal of biotechnology 20070501
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Reusability of entrapped cells of Pseudomonas diminuta for production of 7-aminocephalosporanic acid.
Applied biochemistry and biotechnology 20070401
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Microbial production of 7-amino-cephalosporanic acid and new generation cephalosporins (cephalothin) by different processing strategies.
Artificial cells, blood substitutes, and immobilization biotechnology 20070101
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New active site oriented glyoxyl-agarose derivatives of Escherichia coli penicillin G acylase.
BMC biotechnology 20070101
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[Microspeciation of amphoteric molecules of unusual acid-base properties].
Acta pharmaceutica Hungarica 20070101
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Thermal inactivation of D-amino acid oxidase from Trigonopsis variabilis occurs via three parallel paths of irreversible denaturation.
Biotechnology and bioengineering 20060705
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Spectrophotometric assay for quantitative determination of 7-aminocephalosporanic acid from direct hydrolysis of cephalosporin C.
Analytical biochemistry 20060315
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Enzymatic modifications of cephalosporins by cephalosporin acylase and other enzymes.
Critical reviews in biotechnology 20060101
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Evolution of an acylase active on cephalosporin C.
Protein science : a publication of the Protein Society 20051201
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Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.
Bioscience, biotechnology, and biochemistry 20051001
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Single-step conversion of cephalosporin-C to 7-aminocephalosporanic acid by free and immobilized cells of Pseudomonas diminuta.
Applied biochemistry and biotechnology 20050701
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Reactions of pyrazolylborate-zinc-hydroxide complexes related to beta-lactamase activity.
Inorganic chemistry 20050613
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1H and 13 C spectral assignments of 7beta-(cinnamoyl-substituted)amino-3-acetoxymethyl-cephalosporins.
Magnetic resonance in chemistry : MRC 20050301
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Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101
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D-Amino acid oxidase: structure, catalytic mechanism, and practical application.
Biochemistry. Biokhimiia 20050101
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Toward the development of a cephalosporin-based dual-release prodrug for use in ADEPT.
The Journal of organic chemistry 20041112
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Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase.
Applied microbiology and biotechnology 20040801
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[Compared D-amino acid oxidase expression in different Pichia pastoris host strains].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040701
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Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues.
Biochemical and biophysical research communications 20040625
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Construction and application of fusion proteins of D-amino acid oxidase and glutaryl-7-aminocephalosporanic acid acylase for direct bioconversion of cephalosporin C to 7-aminocephalosporanic acid.
Biotechnology letters 20040601
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Occupational asthma and IgE sensitization to 7-aminocephalosporanic acid.
The Journal of allergy and clinical immunology 20040401
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Affinity labeled glutaryl-7-amino cephalosporanic acid acylase C130 can hydrolyze the inhibitor during crystallization.
Biochemical and biophysical research communications 20040116
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Synthesis and preliminary antimicrobial evaluation of new 7-(N-pyrrolyl) derivatives of cephalosporins.
Arzneimittel-Forschung 20040101
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Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: a comparison between proteins from different sources.
Biotechnology progress 20040101
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Industrial enzymatic production of cephalosporin-based beta-lactams.
Advances in biochemical engineering/biotechnology 20040101
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Deacylation activity of cephalosporin acylase to cephalosporin C is improved by changing the side-chain conformations of active-site residues.
Biochemical and biophysical research communications 20031010
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Multivariate analysis and classification of the chemical quality of 7-aminocephalosporanic acid using near-infrared reflectance spectroscopy.
Analytical chemistry 20030715
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A rapid and specific method to screen environmental microorganisms for cephalosporin acylase activity.
Journal of microbiological methods 20030701
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Industrial production of beta-lactam antibiotics.
Applied microbiology and biotechnology 20030601
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An alternative procedure for preparation of cefdinir.
Farmaco (Societa chimica italiana : 1989) 20030601
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The kinetic properties of the carboxy terminal domain of the Bacillus licheniformis 749/I BlaR penicillin-receptor shed a new light on the derepression of beta-lactamase synthesis.
Molecular microbiology 20030601
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An improved method for preparation of cefpodoxime proxetil.
Farmaco (Societa chimica italiana : 1989) 20030501
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Immobilization of glutaryl-7-aminocephalosporanic acid acylase on silica gel and enhancement of its stability.
Applied biochemistry and biotechnology 20030301
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Cross-reactivity of cefotetan and ceftriaxone antibodies, associated with hemolytic anemia, with other: cephalosporins and penicillin.
American journal of clinical pathology 20020801
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Expression of gene encoding GL-7ACA acylase in Escherichia coli.
Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20020701
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The crystal structure of Helicobacter pylori cysteine-rich protein B reveals a novel fold for a penicillin-binding protein.
The Journal of biological chemistry 20020322
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Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin C.
Protein science : a publication of the Protein Society 20020101
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Active site residues of cephalosporin acylase are critical not only for enzymatic catalysis but also for post-translational modification.
The Journal of biological chemistry 20011221
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Structure of cephalosporin acylase in complex with glutaryl-7-aminocephalosporanic acid and glutarate: insight into the basis of its substrate specificity.
Chemistry & biology 20011201
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[Establishment of detective systems for GL-7ACA acylase expression].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20011101
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Modulation of penicillin acylase properties via immobilization techniques: one-pot chemoenzymatic synthesis of Cephamandole from Cephalosporin C.
Bioorganic & medicinal chemistry letters 20010917
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Improvement of the synthesis of diphenylmethyl 7beta-(o-hydroxy)benzylideneamino-3-hydroxymethyl-3-cephem-4-carboxylate.
Farmaco (Societa chimica italiana : 1989) 20010801
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D-amino-acid oxidase--an improved production of the enzyme by the yeast Trigonopsis variabilis in a laboratory fermentor.
Folia microbiologica 20010101
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Epitope analysis of aztreonam by antiaztreonam monoclonal antibodies and possible consequences in beta-lactams hypersensitivity.
International archives of allergy and immunology 19920101
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[Thoughts on explaining cigarette smoking].
Das Offentliche Gesundheitswesen 19870201
